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Infectious Agents > Exam 4: Haemophilus, Histophilus, Francisellaceae > Flashcards

Exam 4: Haemophilus, Histophilus, Francisellaceae Flashcards

1
Q

What are the serotypes of H. parasuis based on? How are they numbered?

A

“Heat-stable” antigens

Numbered 1-15

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2
Q

What diseases can H. parasuis cause?

A

Sporadic, stress-associated disease in young pigs
Disease outbreaks in non-immune HHS pigs of all ages
Septicemic disease in young weaned pigs (Glasser’s disease)
Acute bronchopneumonia without septicemia

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3
Q

What are the virulence factors of H. parasuis?

A

Capsular polysaccharide
Fimbriae
Lipooligosaccharide
Can survive in phagocytic cells

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4
Q

What is H. felis a common commensal of?

A

The feline URT

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5
Q

What can H. felis cause as an opportunistic pathogen?

A

Conjunctivitis and upper respiratory infection

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6
Q

What does H. felis require for growth?

A

CO2 and V factor

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7
Q

What is H. haemoglobinophilus normal flora of?

A

Canine lower urogenital tract

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8
Q

What can H. haemoglobinophilus cause?

A

Cystitis and neonatal infections

It has been associated with vaginitis

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9
Q

What separates Histophilus somni from other species in the family?

A

Capnophilia
Yellowish pigmentation
Indole production

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10
Q

What are the 2 principal syndromes in bovine caused by Histophilus somni?

A

Pneumonia- BRD

Septicemia and thrombotic meningoencephalitis

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11
Q

What 3 organisms can cause BRD?

A

Histophilus somni
M. haemolytica
P. multocida

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12
Q

What are the virulence factors of H. somni?

A

Nonencapsulated, but expresses LOS
Immunoglobulin binding proteins that bind to Fc regions of bovine Ig
Adheres to endothelial cells, causing contraction, collagen exposure, platelet adehsion, and thrombus formation
Survives in phagocytic cells

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13
Q

What are the subspecies of Francisella tularensis?

A

Tularensis
Holartica
Mediasiatica

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14
Q

What can F. tularensis tularensis and F. tularensis holartica cause?

A

Tularemia

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15
Q

Which subspecies of F. tularensis is considered to the more virulent and predominant in North America? What is its reservoir?

A

Tularensis

Lagomorphs

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16
Q

Which subspecies of F. tularensis is considered to the more virulent and predominant in Europe and Asia? What is it carried by?

A

Holartica

Rodents

17
Q

What is the natural reservoir for F. tularensis?

A

Lagomorphs and rodents

18
Q

What is the most common disease caused by F. tularensis?

A

Ulceroglandular

19
Q

What is the transmission of F. tularensis?

A

Contact with infected animals or discharges

20
Q

What is the primary reservoir of F. tularensis in the US?

A

Cottontail rabbits

21
Q

What are the clinical signs of Glasser’s disease?

A 
Sudden death
Neurologic signs
Anorexia
Lameness
Joint swelling
Dyspnea
Fever
Abortion
22
Q

What causes disease outbreaks in high health status swine herds?

A

A. suis and H. parasuis

Infectious Agents (38 decks)

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