Exam 3: Gammaproteobacteria

Question 1

Is Pasteurella multocida zoonotic?

Answer 1

Yes

Question 2

What are the antigenic types (A, B, D, E, F) of P. multocida based on?

Answer 2

Capsular polysaccharides

Question 3

What disease is associated with type A P. multocida?

Answer 3

Fowl cholera

Question 4

What disease is associated with type B P. multocida?

Answer 4

Hemorrhagic septicemia

Question 5

What disease is associated with type D P. multocida?

Answer 5

Atrophic rhinitis

Question 6

What disease is associated with type E P. multocida?

Answer 6

Hemorrhagic septicemia

Question 7

What is the endotoxin of P. multocida like?

Answer 7

LPS O side chains are shorter than the Enterobacteriaceae, which makes the surface more hydrophobic and permeable

Question 8

What is required for the virulence of P. multocida?

Answer 8

Capsulr polysaccharide

Question 9

What do P. multocida type D strains produce?

Answer 9

A thermolabile dermonecrotoxin that plays a role in atrophic rhinitis of swine

Question 10

What are the serotypes associated with hemorrhagic septicemia?

Answer 10

B:2 in Asia
E:2 in Africa

Question 11

What does hemorrhagic septicemia primarily affect?

Answer 11

Cattle and water buffalo

Question 12

Where does hemorrhagic septicemia occur?

Answer 12

In tropical and subtropical zones during rainy season

Question 13

What is hemorrhagic septicemia transmitted by?

Answer 13

Ingestion or inhalation by direct contact or via fomites

Question 14

Where can P. multocida as a primary agent survive?

Answer 14

In damp soil or water

Question 15

What facilitates the transmission of hemorrhagic septicemia?

Answer 15

Rain and high humidity

Question 16

What are the clinical signs associated with hemorrhagic septicemia?

Answer 16

Fever
Dullness
Reluctance to move
Salivation
Profuse serous nasal discharge
Edema

Question 17

What can hemorrhagic septicemia cause?

Answer 17

Respiratory disease in cattle

Question 18

What are the primary serotypes of fowl cholera?

Answer 18

A:1
A:3
A:4

Question 19

Describe the transmission of fowl cholera

Answer 19

Carrier birds maintain the pathogen, transmission occurs by oral and respiratory routes
Wild birds may be a source of infection to commercial poultry

Question 20

What are the 4 forms of disease of fowl cholera?

Answer 20

Peracute
Acute
Subacute
Chronic

Question 21

Describe the peracute form of fowl cholera

Answer 21

Up to 60% of mortalities without preceding signs

Question 22

Describe the acute form of fowl cholera

Answer 22

Depression, sleepiness, anorexia, diarrhea
Death can result in a few hours or 2-3 days
Flock mortalities can be 30%

Question 23

Describe the subacute form of fowl cholera

Answer 23

Respiratory

Pneumonia is especially common in turkeys

Question 24

Describe the chronic form of fowl cholera

Answer 24

Localized caseous lesions in the respiratory tract and conjunctiva
Swollen wattles, joints, and footpads may be swollen from fibrinosuppurative exudate

Question 25

What is atrophic rhinitis caused by in swine (severe form)?

Answer 25

Toxigenic P. multocida serotype D in association with Bordetella bronchiseptica

Question 26

Describe the less severe form of atrophic rhinitis

Answer 26

Mild to moderate turbinate atrophy can be caused by B. bronchiseptica

Question 27

Which serotypes are associated with opportunistic infections (BRD and porcine pneumonia)?

Answer 27

A