Exam 3: Gammaproteobacteria Flashcards
Is Pasteurella multocida zoonotic?
Yes
What are the antigenic types (A, B, D, E, F) of P. multocida based on?
Capsular polysaccharides
What disease is associated with type A P. multocida?
Fowl cholera
What disease is associated with type B P. multocida?
Hemorrhagic septicemia
What disease is associated with type D P. multocida?
Atrophic rhinitis
What disease is associated with type E P. multocida?
Hemorrhagic septicemia
What is the endotoxin of P. multocida like?
LPS O side chains are shorter than the Enterobacteriaceae, which makes the surface more hydrophobic and permeable
What is required for the virulence of P. multocida?
Capsulr polysaccharide
What do P. multocida type D strains produce?
A thermolabile dermonecrotoxin that plays a role in atrophic rhinitis of swine
What are the serotypes associated with hemorrhagic septicemia?
B:2 in Asia
E:2 in Africa
What does hemorrhagic septicemia primarily affect?
Cattle and water buffalo
Where does hemorrhagic septicemia occur?
In tropical and subtropical zones during rainy season
What is hemorrhagic septicemia transmitted by?
Ingestion or inhalation by direct contact or via fomites
Where can P. multocida as a primary agent survive?
In damp soil or water
What facilitates the transmission of hemorrhagic septicemia?
Rain and high humidity
What are the clinical signs associated with hemorrhagic septicemia?
Fever Dullness Reluctance to move Salivation Profuse serous nasal discharge Edema
What can hemorrhagic septicemia cause?
Respiratory disease in cattle
What are the primary serotypes of fowl cholera?
A:1
A:3
A:4
Describe the transmission of fowl cholera
Carrier birds maintain the pathogen, transmission occurs by oral and respiratory routes
Wild birds may be a source of infection to commercial poultry
What are the 4 forms of disease of fowl cholera?
Peracute
Acute
Subacute
Chronic
Describe the peracute form of fowl cholera
Up to 60% of mortalities without preceding signs
Describe the acute form of fowl cholera
Depression, sleepiness, anorexia, diarrhea
Death can result in a few hours or 2-3 days
Flock mortalities can be 30%
Describe the subacute form of fowl cholera
Respiratory
Pneumonia is especially common in turkeys
Describe the chronic form of fowl cholera
Localized caseous lesions in the respiratory tract and conjunctiva
Swollen wattles, joints, and footpads may be swollen from fibrinosuppurative exudate
What is atrophic rhinitis caused by in swine (severe form)?
Toxigenic P. multocida serotype D in association with Bordetella bronchiseptica
Describe the less severe form of atrophic rhinitis
Mild to moderate turbinate atrophy can be caused by B. bronchiseptica
Which serotypes are associated with opportunistic infections (BRD and porcine pneumonia)?
A
