Exam 2: Streptococcus Flashcards
What is the result of streptococcus in a gram stain? Catalase test?
Positive
Negative
What does most streptococcus require to grow?
Blood or serum
When does streptococcus not grow?
When shed into the environment
What is used when streptococcus is classified by the Lancefield’s serological groups?
Cell wall antigens
Serological agglutination
What does antigenic specificity, used in Lancefield’s serological groups, reside in?
Polysaccharides attached to teichoic acid layer of cell wall, so called “C” substance (for carbohydrate)
What are the virulence factors for streptococcus?
Capsules: hyaluronic acid is non-immunogenic and non-antigenic, act as an adhesin and are antiphagocytic
M proteins, lipoteichoic acid, and other cell wall proteins with fimbriae cause adherence and are antiphagocitic
What group species is S. pyogenes?
Only group A species
What kind of pathogen is S. pyogenes?
Mostly human
What is the major virulence factor of S. pyogenes?
Over 60 different M proteins
Why are there no vaccines available for S. pyogenes?
Immunity is type-specific and there are so many M proteins that it is difficult to develop a vaccine
What group species is S. agalactiae?
Only group B species
What is used in late pregnancy?
Group B strep test
What species is related to CAMP factor?
S. agalactiae
What does CAMP factor cause?
Complete lysis of cow or sheep RBC in the presence of S. aureus beta hemolysin producing arrowhead appearance of enhanced hemolysis
What kind of pathogen is S. agalactiae?
Obligatory intramammary