Exam 2 PPTs - 8 Flashcards
Human races are not like dog breeds: refuting a racist analogy:
- dogs factored greatly into Darwin’s conception of evolution and he specifically pondered the similarities of … and dog breeds in The Descent of Man
- J.B.S. Haldane posed a question to a group of anthropologists at the Royal Society in 1956: “Are the biological differences between human groups comparable with those between groups of domestic animals such as greyhounds and bulldogs?”
- is race fundamentally … or a …?
human races;
biological;
social construct
Human races are not like dog breeds: refuting a racist analogy:
- compare genotypic and phenotypic variation within and between human groups and within and between dog breeds
- demonstrate the fundamental biological differences between … in the two different species
- fundamental distinctions between “race” in humans and dog breed categories
- discuss the sociocultural significance of this analogy and the importance of its refutaiton
patterns of variation
Population structure of human races and dog breeds:
- A key assumption of the race-breed analogy is that both human “races” and dog breeds are formed and structured in similar ways
- If this assumption holds, then one expects to observe both high levels of … and low levels of …
- this predicts that groups (whether races or breeds) are clearly distinguishable from each other while at the same time also being internally very similar
among-group diversity;
within-group diversity
Population structure of human races and dog breeds:
- patterns of among- versus within-group genetic diversity can be assessed using various tools and methods from the field of population genetics.
- Fst statistic and analysis of molecular variance (AMOVA) allow one to investigate patterns of …
- higher Fst values indicate a more … population
- AMOVA allows a researcher to partition the total amount of … in a sample into different levels
among versus within-group genetic diversity;
structured;
genetic variation
Population structure of human races and dog breeds:
Genetic diversity in Dogs:
- within-breed genetic variation was …
- Fst estimates indicated high levels of … among breeds
- AMOVA: about 27% of variation among dogs could be attributed to …
low;
differentiation;
variation across breeds
Population structure of human races and dog breeds:
Genetic diversity in Humans:
- 4/5/7 broad geographical groups(populations) depending on the method and the data
- Within-group genetic variation was …
- Fst values between continental groups are far …
- AMOVA: differences among these groups accounted for only 3.3 - 4.7% of the variation. variation within populations accounts for about 92.9 - 94.3%
high;
lower
Population structure of human races and dog breeds:
Genetic diversity in Humans vs. Dogs:
- greater degree of global genetic variation in humans can be attributable to variation … rather than …
within local populations; between regional (racial) groups
Population structure of human races and dog breeds:
Genetic diversity in Humans vs. Dogs:
- greater degree of global genetic variation in humans can be attributable to variation within local populations rather than between regional groups
- substantial … can be found within these groups
- lower levels of … observed within dog breeds
- large amount of genetic variation that can be explained by …
heterogeneity;
heterozygosity;
breed differences
Population structure of human races and dog breeds:
Genetic diversity in Humans vs. Dogs:
- within the US, racial categories (as recognized by the US census) have shifted over time, reflecting concerns about slavery, immigration and access to resources
- alongside that ongoing history, there has been disagreement among geneticists about how human genetic variation is patterned, most famously between lewontin and edwards
- marks wrote: “The point of the biological theory of race was to discover large clusters of people that are principally … within and … between contrasting groups. Lewontin’s analysis shows that such groups do not exist in the human species, and Edwards’ critique does not contradict that interpretation”
homogenous;
heterogeneous
Origins and evolution of biological variation within humans and domestic dogs:
- present human biogeographic variation has been shaped by Late Pleistocene … and …, …, …, …, … and … with other species, not to mention …
migration; gene flow; genetic isolation; genetic drift; selection; epigenetic change; coevolution; culture
Origins and evolution of biological variation within humans and domestic dogs:
- a number of very rare (and usually very young) alleles may be …, the majority of common genetic variants are not private to a particular continent, and are often shared across multiple regions
- in contrast with dogs, no modern human populations have ever been … over many generations
geographically localized;
completely reproductively isolated
Origins and evolution of biological variation within humans and domestic dogs:
- while the so-called “ancient breeds” like chow chows and salukis are as old as a few 1000 years, most dog breeds are younger than few 100 yrs
- some breeds (e.g. the Bernese mountain dog) arose by … breeds while others were bred from exiting breeds to …
- breeds arise due to breeders’ extreme control of … to maximize the presence of desired traits in the next generation of dogs
hybridizing;
serve a particular role;
mating
Origins and evolution of biological variation within humans and domestic dogs:
- in this process of …, dogs are prevented from mating outside their breed and only a limited number of animals are permitted to reproduce within a breed
- intense … is one of the main reasons why dogs have over 1000 inherited diseases and health disorders
artificial selection;
inbreeding
Genotype-phenotype relationships in comparable dog and human traits that vary:
- historically, human racial classifications included some combination of … characteristics, like pigmentation and body size and shape
- exploring the biology underlying these characteristics helps refute the human race dog breed analogy
- skin and hair color: controlled by … of genes in humans, … genes in dogs
physical;
dozens;
nine
Genotype-phenotype relationships in comparable dog and human traits that vary:
- exploring the biology underlying these characteristics helps refute the human race dog breed analogy
- the same goes for height, with humans having significant overlap among populations: it takes more than … genetic loci to explain only half of human height variation, only … major genetic loci explain roughly 50% the variation in size between breeds
400;
six