Exam 2 Lecs - 7 Flashcards
Evolutionary tree for the different coronaviruses
- … and … were recently evolved and infect mammals
- oldest coronaviruses are found in and originated in …
alpha; beta;
birds
viruses can easily …
cross taxonomic boundaries
corona genome:
- contains instructions to make …, … and …, …
spike protein;
membrane; capsid;
envelope
corona genome:
- around … bp
- spike protein allows virus to …
30,000;
invade cells
corona genome:
- … keeps the genome the way it is - prevents changes in a way
purifying selection
it’s better to use … substitutions to determine divergence time due to …
synonymous;
neutral theory of evolution
it’s better to use synonymous substitutions to determine divergence time due to neutral theory of evolution:
- synonymous substitutions occur at a …
- they keep accumulating in history of divergence
- more associated with … than nonsynonymous, bc non will be … and they won’t be ‘seen’
steady rate;
time;
removed
humans started getting more diseases when they started …
- most human viruses originated …
domesticating animals;
in animals
excess deaths increased from …
epicenter of virus (i.e. Huanan market) outwards
if virus started infecting humans when it was already at the …, its infectiousness could not further increase
- if virus is too … - it won’t be able to spread –> kills individual before spreading
peak of the adaptive landscape;
deadly
earliest accepted dog date is around …
- when humans first started domesticating dogs, difficult to differentiate between dogs and …. thus, this time frame is the oldest date when we can say for sure that the organism is a dog
15,000 ya;
wolves
350 dog breeds created via …
artificial selection
comparing the 85 breeds to wolves to figure out closest relatives to dogs:
- dogs formed …/… that are mostly based on the … of dog
distinctive clades/monophyletic groups;
type
comparing the 85 breeds to wolves to figure out closest relatives to dogs:
- … are the outgroup on this phylogenetic tree
- one of the most ancient lineages of dogs is …, an African dog
- … and … breeds all developed early in history of odgs
coyotes;
basenji;
ancient; spitz
comparing the 85 breeds to wolves to figure out closest relatives to dogs:
- explosion of different breeds that mostly came after 1800s, most with … origins
- PCA - decomposes … of dataset (in this case, genetic data set) into a coordinate
European;
variance