Exam 1 Lecs - 4 Flashcards

1
Q

evidence of founder:
- Polynesian field crickets: native to … and …
found on …, including …

A

Australia;
New Guinea;
Pacific Islands;
Hawaii

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

evidence of founder:
Polynesian Field Crickets:
- Crickets dispersed across the Pacific Islands:
expectation is that there’s …/… on the islands, we expect to find … and we expect to see …/…

A

drift; founder events;
small number of alleles;
fixed/lost alleles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

evidence of founder:
Polynesian Field Crickets:
Crickets dispersed across the Pacific Islands:
- Each island’s population would likely have been founded by a …
- sampled 394 crickets from 19 pops at seven … (…, can’t be under …, …)

A
small number of individuals; 
microsatellite loci; 
noncoding DNA; 
selection; 
neutral
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

evidence of founder:
Polynesian Field Crickets:
Crickets dispersed across the Pacific Islands:
- sampled 394 crickets from 19 pops at seven microsatellite loci (noncoding DNA, can’t be under selection, neutral):
microsatellites have many ….

Sampled mainland Australia and the pacific islands –> For the mainland samples, frequency of alleles was … But in Pacific Islands, we see … of …

A

easily identifiable alleles;
distributed more among numerous alleles;
higher frequency; fewer alleles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

evidence of founder:
Polynesian Field Crickets:
Sampled mainland Australia and the Pacific Islands:
- For the mainland samples, frequency of alleles was distributed more among numerous alleles. But in Pacific Islands, we see higher frequency of fewer alleles –> islands have … and … alleles with … –> some alleles from mainland … in island populations
This is evidence of founder events and the impact of drift over several gens

A

less genetic diversity;
fewer;
higher frequencies;
aren’t present

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Evidence of founder:
Pingelapese people of Eastern Caroline Islands:
- population made up of survivors of …
- … occurred also
- among survivors were carriers of a … allele in … cells

A

typhoon;
famine;
recessive loss of function;
cone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Evidence of founder:
Pingelapese people of Eastern Caroline Islands:
- among survivors were carriers of a recessive loss of function allele in cone cells (i.e. cells that enable us to see …) –> people with that gene have … cone cells and …

A

color;
non-functioning;
extreme sensitivity to light

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Evidence of founder:
Pingelapese people of Eastern Caroline Islands:
Among survivors were carriers of a recessive loss of function allele in cone cells (i.e. cells that enable us to see color)
- completely … with … as well
- condition is called …

A

color blind;
poor vision;
achromatopsia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Evidence of founder:
Pingelapese people of Eastern Caroline Islands:
- Condition called achromatopsia: …, frequency is … people worldwide. However, in the Pingelapese the frequency is …

A

rare;
1/20,000;
1/20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Evidence of founder:
Pingelapese people of Eastern Caroline Islands:
- … by the typhoon, a founder event, left the allele at a frequency of at least …. It’s now more than …

A

sampling error;
2.5%;
20%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Evidence of founder:
Pingelapese people of Eastern Caroline Islands:
Sampling error by the typhoon, a founder event, left the allele at a frequency of at least 2.5%. It’s now more than 20%:
- this change in frequency: no … to island so no new alleles coming in, the key point though is = …(it’s …)

A

migration;
random drift;
increasing by chance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Evidence of founder:
Pingelapese people of Eastern Caroline Islands:
- this change in frequency due to random drift: when the population is very small, … is not strong enough to reduce frequency of the allele. … is stronger in smaller populations

A

selection;

drift

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Evidence of founder:
controlled lab experiment on fruit flies:

Buri studied … and … empirically

A

random fixation;

loss of heterozygosity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Evidence of founder:
controlled lab experiment on fruit flies:

Buri studied random fixation and loss of heterozygosity empirically:

  • established 107 pops of flies, .,.. and … as starting population
  • All of the founders were … for brown eyes (allele …)
A

8 males;
8 females;
heterozygous;
bw75

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Evidence of founder:
controlled lab experiment on fruit flies:
Buri established 107 populations of flies, 8 males and 8 females as starting population:
- he maintained these pops for … generations and kept the population size at … by picking 8 females and 8 males …

A

19;
16;
at random

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Evidence of founder:
controlled lab experiment on fruit flies:

Buri maintained these pops for 19 generations and kept the population size at 16 by picking 8 females and 8 males at random –> what results would we predict for allele bw75? A: It can … or … since it’s …

Over the generations, most populations had either … the frequency of the allele or … the frequency of the allele

A

either increase; decrease; random;
fixed;
lost

17
Q

Evidence of founder:
a controlled lab experiment on fruit flies:
Why is the number of populations with frequency 0 is approximately the same as frequency 1?
- partly bc its …
- primarily bc … of the allele was …

A

random;

initial frequency; 0.5

18
Q

Evidence of founder:
controlled lab experiment on fruit flies:
Why is the number of populations with frequency 0 is approximately the same as frequency 1?
- primarily bc initial frequency of the allele was 0.5. From the beginning, half of the alleles were bw and half were bw75. Equal chances of either … or …
If initial frequency was about 0.9 for bw75, you’d expect to have more populations …

A

fixing;
being lost;
fixing the allele

19
Q

Evidence of founder:
controlled lab experiment on fruit flies:
What happens to heterozygosity as bw75 is drifting toward fixation or loss in the population?
- …
- heterozygosity plot is similar to a … with …

A

decreases;
straight line;
negative slope

20
Q

Evidence of founder:
controlled lab experiment on fruit flies:
… acted as one of the main forces of evolution in Buri’s flies and it was …

A

drift;

totally random

21
Q

Evidence of founder:
Natural experiment looking at the same things:
Alan Templeton tested predictions about … in Missouri’s Ozark mountains
This region is now mostly forest and savannah nviro
between 8000 and 4000 ya, … invaded the desert region. But then, climate changed again and … began invading the region again

A

random fixation of alleles;
forest;
savannah

22
Q

Evidence of founder:
Natural experiment looking at the same things:
Exposed rocky outcrops called the … In those isolated pockets of desert, can find populations of …
In the 50s, they … in this environment

A

glades;
collared lizards;
suppressed fire

23
Q

Evidence of founder:
Natural experiment looking at the same things:
In the 50s, they suppressed fire in this environment:
- lizards could migrate between those outcrops when … occur. Suppressing fires … the lizards more - …

A

fires;
isolated;
stopped migration

24
Q

Evidence of founder:
Natural experiment looking at the same things:
In the 50s, they suppressed fire in this environment:
- they then sampled the lizards and sequenced the DNA at MDH, mtDNA (mitochondrial) and rDNA(ribosomal), looking at … in those regions
- found that in several outcrops, the individuals were … genetically –> this is bc pop is …, there’s …, and alleles are being … and there’s no …

A
variants; 
all the same; 
small; 
drift; 
fixed; 
migration
25
Evidence of founder: Natural experiment looking at the same things: In the 50s, they suppressed fire in this enviro: - found that in several outcrops, the individuals were all the same genetically. ... in populations is also due to drift, too - proposed that the nearly complete loss of ... in those populations doomed the lizards to ...
differences; genetic diversity; extinction
26
Evidence of founder: Natural experiment looking at the same things: - Proposed that the nearly complete loss of genetic diversity in those populations doomed the lizards to extinction: suggested that local extinctions would occur through two forces: ..., changes in ... and ...
pathogens; | biological; physical environment
27
Evidence of founder: Natural experiment looking at the same things: - proposed that the nearly complete loss of genetic diversity in those populations doomed the lizards to extinction. Suggested that local extinctions would occur through two forces: pathogens, changes in biological and physical environment - pathogens are an issue bc there can't be any ... without ... --> if pathogen can kill one lizard from that population, since they're all the same, it'll .... - Same reasoning for changes in enviro
selection; genetic variation; kill all of them
28
Evidence of founder: Natural experiment looking at the same things: - They surveyed more glades. Consistent with their expectations, ... of the glades had ...
2/3rds; | no lizards
29
Young and colleagues reviewed evidence of these processes among populations of various sizes: - compiled data on three ... and a ... Plotted measures of ... against ...
flowering herbs; tree; diversity; population size
30
Young and colleagues reviewed evidence of these processes among populations of various sizes: Compiled data on three flowering herbs and a tree. Plotted measures of diversity against pop size - there is a correlation where, as size increases, diversity ... (vice versa too): small sizes: drift .... as some alleles are fixed and others lost size of population can be measured from .../... --> the ...
increases as well; removes variation; genetic diversity; polymorphism; effective population size
31
Effective pop size: size of an ideal ... that would ... at the same rate as an ...
theoretical population; lose heterozygosity; actual population of interest
32
effective pop size: measure of variation is proportional to ... --> can measure population size with ... This is a ... number though so the effective pop size is pretty much always ... than the actual size
size of population; genes; theoretical; smaller
33
effective pop size: -For humans, all the genetic diversity we have among 7 billion people is actually equivalent to an idealized population size of ... --> we're ...
100,000; | very similar
34
random drift: bc fluctuations in allele - frequency are random, every population follows a ... evolutionary path - Genetic drift is more ... and ... in small populations than large
unique; rapid; dramatic
35
random drift: - Genetic drift is more rapid and dramatic in small populations than large: in small populations, have ... Bigger sample has ... --> if you take a larger sample of a population, that sample is a ... of that population
higher sampling error; smaller error; better representation
36
random drift: - given sufficient time, drift can produce substantial changes in ... even in populations that are ... --> drift is ... in larger populations but it still changes ... with enough time (will be ... needed for larger populations)
``` allele frequencies; fairly large; weaker; allele frequencies; more time ```