Exam 2: Nerves Flashcards
Cell body
spherical, ovoid, or angular
trophic, metabolic center
Most protein synthesis occurs here (Golgi apparatus, mitochondria, basophilic clumps, free ribosomes)
Nissl bodies
stacks of rER
nucleus
large, clear, euchromatic, dense nucleolus
neurons do not form tumors because
typically neurons in adults do not divide (mitosis), however some neural stem cells and glial cells can divide and differentiate into nerve cells
lipofuscin
yellowish-brown pigment, lysosomal enzymatic reisdue
melanin granules
pigment present in certain neurons (substantia nigra)
Axon hillock
origin of axon, funnel-shaped, pale - no rER
chromatolysis
dissolution of Nissl substance following injury
dendrites
radiate from soma, branch and taper, increase receptive area of neuron, usually no GA
never myelinated - receive stimuli and transmit information to cell body
Axon
cylindrical, varies in length
no rER, contains microtubules, neurofilaments, and vesicles
Relays action potentials away from cell body to axon terminals
axolemma
axon cell membrane - specialized for impulse conduction
axoplasm
axon cytoplasm
initial segment
segment of axon between axon hillock and where myelination begins
action potential initiated here
Axoplasmic transport
transport of macromolecules, organelles, and vesicles along axon
anterograde transport
away from cell body
uses Kinesin
slow or fast transport systems
Kinesin
microtubule-associated motor protein used in anterograde transport
slow transport system
carries tubulin molecules, actin molecules, and neurofilament proteins from cell body to terminal boutons
retrograde transport
towards cell body
uses Dynein
Dynein
microtubule-associated motor protein used in retrograde transport
fast transport system
bidirectional
carries membranous organelles, sugars, aa, nucleotides, neurotransmitters, and calcium
requires ATP
bipolar neurons
2 processes - one dendrite and axon
In retina, inner ear, nose - senses of smell, vision, hearing, and balance
multipolar neurons
most common type
numerous dendrites and single axon
unipolar (pseudounipolar) neurons
single process (axon) arising from cell body which separates into 2 processes impulses bypass the cell body Enclosed in sensory ganglia and DRG