Exam 1: Epithelium Flashcards

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1
Q

Simple squamous

A

epithelium

blood-brain barrier, filtration, exchange

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2
Q

Simple cuboidal

A

Thyroid follicles, renal tubules, ducts of glands

Absorption, secretion, barrier, conduit

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3
Q

Simple columnar nonciliated

A

stomach & intestines

absorption, secretion, barrier

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4
Q

Simple columnar ciliated

A

uterine tubes

absorption, secretion, barrier

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5
Q

Pseudostratified columnar

A

Trachea, bronchi, ducts of male reproductive system (with sterocilia)
Secretion, absorption, barrier, transport

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6
Q

Stratified squamous

A

nonkeratinized - esophagus, distal anal canal, vagina

keratinized - epidermis

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7
Q

Transitional (urothelium)

A

Ureters, urinary bladder, urethra

Barrier, protection, distension

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8
Q

Simple

A

one layer all cells on basement membrane

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9
Q

Stratified

A

2 or more strata

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10
Q

Pseudostratified

A

one layer, nuclei at different levels

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11
Q

Cilia

A

motile and nonmotile (primary cilia)

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12
Q

Kartagenar syndrome

A

defective dynein arms lead to immotile cilia and flagella - respiratory infections, bronchiectasis, chronic sinusitis, situs inversus (reversal of organs)

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13
Q

Flagella

A

whip-like
one per cell
9+2 arrangement of microtubules

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14
Q

Microvilli

A

can be separated from one another and brought closer- interaction with terminal web

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15
Q

Stereocilia

A

elongated microvilli
nonmotile
inner ear

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16
Q

Zonula occludens

A

Tight junction - made of Claudins and occludins

selective movement, establish functional polarity, prevent cells from separating

17
Q

Zonula adherens

A

Intracellular anchor proteins - alpha and beta catenins, actinin, vinculin - actin microfilaments attach to these sites & form terminal web
Transmembrane adhesion - E-cadherin

18
Q

Macula adherens (desmosome)

A

Intracellular anchor - desmoplakins and plakoglobin - intermediate filaments attach at these sites
Transmembrane adhesion - cadherin family

19
Q

pemphigus vulgaris

A

antibodies against desmoglein 3 - blistering of ski

20
Q

Focal adhesions

A

anchors cell to proteins of EC matrix
actin filaments attach
integrin family anchors cell to proteins of EC matrix

21
Q

Hemidesmosome

A

anchors basal plasma membrane of cell to basal lamina
Intermediate filaments attach to plectin and BP230
integrin family and collagen interact with extracellular matrix

22
Q

Nexus gap junctions

A

connexon fromed from connexins

electrical and chemical communication