Exam 1 Flashcards
4 basic tissues of human body
Epithelial
Muscle
Neural
Connective
Osteoblasts function
Form bone
Osteocyte function
Maintain/ nurture bone
Osteoclasts function
Remodel bone
Primary constituent of ground substance
GAGS
Types of GAGs predominate in bone
Chondroitin sulfate
Keratin sulfate
Hyaluronic acid
Principal type of protein fiber in bone
Collagen type 1
Most frequently described deposit in bone
Hydroxyapatite
Bone is also repository for these ions…
Sodium Magnesium Fluoride Lead Strontium Radium
Wolff’s Law
Living tissue will respond to stressors such as anxiety, tension, or pressure
Bone is formed or absorbed in response to these same stressors
3 responses of “living” bone
Heal
Remodel under stressors (anxiety, tension, pressure)
Age
Bone is embryological derivative of which CT?
Mesenchyme and/or cartilage
Name given to patter of ossification in mesenchyme
Intramembranous ossification
Timing for appearance of intramembranous ossification
2-3 months in utero
What part of axial skeleton is primarily formed by intramembranous ossification?
Skull
Name given to pattern of ossification in cartilage
Endochondral ossification
Timing for appearance of ossification in cartilage
2-5 months in utero
Which skull bones are ossified by both endochondral and intramembranous ossification?
Mandible
Sphenoid
Temporal bone
Occipital bone
Which bone of appendicular skeleton is formed by both endochondral and intramembranous ossification?
Clavicle
Names given to centers of ossification based on time of appearance?
Primary centers- appear before birth
Secondary centers- appear after birth
Mature bone composed of what areas based on bone density?
Cortical/compact bone
Spongy/cancellous/trabecular bone
Name given to bone below an articulating surface?
Subchondral bone
Name of outer fibro-cellular covering of bone
Periosteum
Name given to fibro-cellular lining of bone
Endosteum
Primary sources of variation observed in bone
Sexual dimorphism
Ontogenic variation
Geographic/population-based variation
Idiosyncratic variation
Sexual Dimorphism
Differences based on gender
Ontogenic variation
Differences based on age or developmental variation
Geographic Variation
Differences based on ethnicity or locational variation
Idiosyncratic variation
Differences based on uniqueness between individuals
Primary constituent of bone mineral
Calcium
Phosphate
Citrate
Carbonate ions
Bone cells embedded in….
Amorphous matrix consisting of ground substance, protein fibers, and various minerals
6 classifications of bone
Long bones Short bones Flat bones Irregular bones Paranasal sinus/pneumatic bones Sesamoid bones
Which classification of bone are characteristic of appendicular skeleton?
Long bones, short bones, sesamoid bones
What is characteristic feature of long bone?
Longer than it is across
Names given to parts of long bone
Diaphysis (shaft) 2 epiphyses (extremities)
Primary characteristic of short bones
Cuboidal
Examples of short bones
Most bones of carpus and tarsus
Characteristic of sesamoid bones
Bone develops within tendon
Examples of sesamoid bone
Patella
Pisiform
Classifications of bones characteristic of axial skeleton
Flat, irregular, paranasal sinus/pneumatic bones
What are flat bones?
Thin layer of spongy bone between 2 layers of compact bone
Examples of flat bone
Parietal bone
Sternum
Characteristic of irregular bone
Numerous projections/ irregular outlines
Examples of irregular bones
Vertebrae
Innominate bones
Characteristic of pneumatic bone
Air spaces within bone
Examples of pneumatic bone
Frontal, ethmoid, maxilla, sphenoid, temporal
What bones contain paranasal sinuses?
Frontal, ethmoid, maxilla, sphenoid
Classifications given to abnormal bone
Accessory and heterotopic bone
Name given to bone formed from existing bone
Accessory bone
Examples of accessory bone
Para-articular processes and bony spurs of vertebrae
Name given to bone formed in non-bone location
Heterotopic bone
Examples of heterotopic bone
Calcific deposits in pineal gland, heart, and ligaments
How many bones form appendicular skeleton
126
How many bones form axial skeleton
80
What bones form axial skeleton
Skull, hyoid, vertebral column, sternum
Long bone definition
Length of the bone is greater than the breadth
Consists of shaft (diaphysis) and two ends (epiphyses)
Short bone definition
Appearance is cuboidal
-Ex: carpus and tarsus
Sesamoid bone definition
Round or oval bones located within tendons
Sesamoid bone examples
Patella, pisiform, and fabella
- also between metacarpals/tarsals and proximal phalanges of hand and foot
Flat bone definition
Thin layer of spongy bone sandwiched between two layers of compact bone
**can be curved
Spongy bone of “flat” bone
Diploe
Irregular bone definition
Numerous projections or irregular outlines
Irregular bone examples
Scapula
Skull bones (except parietal bone)
Vertebrae
Paranasal bone
Associated with paranasal sinuses
Paranasal bone examples
Frontal
Ethmoid
Maxilla
Sphenoid
Pneumatic bone
Exhibits small air spaces within the bone
Pneumatic bone examples
Frontal, ethmoid, maxilla, sphenoid, temporal
Accessory bone
Formed from periosteum of existing bone
Accessory bone examples
Para-articular processes
Bony spurs
Heterotopic bone
Formed from cells within nonbone-related tissues as a result of healing process, disease, stress, and/or age
Location examples of heterotopic bone
Pineal gland
Heart
Ligaments
Four general categories of surface features of bones
Elevations
Depressions
Tunnels/passageways
Facets
Axial skeleton components
Skull Hyoid bone Vertebral column Sternum Ribs
Number of bones in axial skeleton
80
Number of bones in appendicular skeleton
126
3 parts of skull classification
Neurocranium
Facial skeleton/splanchnocranium
Auditory ossicles
Number of bones in skull
28
**sometimes 22 if not counting auditory ossicles
Neurocranium definition
Bones that surround brain (8)
Neurocranium bones
Ethmoid, sphenoid, occipital, frontal (unpaired)
Temporal and parietal (paired)
Facial skeleton/splanchnocranium
Bones that support the face/front of the head (14)
Facial skeleton/splanchnocranium bones
Vomer and mandible (unpaired)
Nasal, lacrimal, palatine, maxilla, zygomatic and inferior nasal concha (paired)
Splanchnocranium (visceral cranium)
Consists of the bones of the facial skeleton minus the mandible
Auditory ossicles
Bones of middle ear located within temporal bone
Auditory ossicle names
Stapes (stirrup)
Incus (anvil)
Malleus (hammer)
**all paired
Hyoid bone location
Below the tongue and above the larynx
Number of bones in adult vertebral/spinal column
26
Number of bones in spine
24
**sacrum and coccyx left out
Sternum regions
Manubrium sterni
Corpus sterni (gladiolus/body)
Xiphoid process
Number of ribs
24 ribs (12 pairs)
Number of adolescent vertebrae
33 segments
Number of vertebrae in adult
26 segments
What constitutes the spine?
24 presacral segments; cervical, thoracic, and lumbar vertebrae
How many segments unite to form the typical sacrum?
5 segments
How many segments unite to form the coccyx?
4 segments
What does ‘cervical’ refer to?
Region of neck
Typical number of segments in cervical region?
7 segments
What does ‘thoracic’ refer to?
Breast plate or chest
Other term used to ID vertebral segments of the chest?
Dorsal segments
Number of segments in dorsal/thoracic region
12 segments
What does ‘lumbar’ refer to?
Region between rib and hip
Number of segments in lumbar region
5 segments
What does ‘sacrum’ mean
Holy bone
What does coccyx refer to
Cuckoo bird’s bill
Which region of the spine is more stable in terms of the number of segments/vertebrae?
Cervical region
Length of typical male spinal column
70 cm
Length of typical female spinal column
60 cm
Difference in length between male and female spinal column
3 inches
Length of male cervical region
12 cm
5 in
Length of male thoracic region
28 cm
11 in
Length of male lumbar region
18 cm
7 in
Length of male sacrum
12 cm
5 in
What is the length of the male spine?
58 cm
23 in
How does the vertebral column participate in protection of neural tissues?
Spinal cord and beginning PNS are located in vertebral segments
How does vertebral column participate in protection of viscera?
Ribs are attached to vertebrae to form the thorax plus protecting the heart and lungs
What parts of the body are supported by vertebral column?
Head, upper extremities, ribs, viscera, and pelvis
How does the vertebral column participate in skeletal formation?
Ribs are formed from the costal process of embryonic vertebral template
What levels of vertebral column specifically accommodate weight-bearing transfer?
S1-S3 at Auricular surface
Motion
Movement without travel
Locomotion
Movement to a new site or location
What is responsible for shape and position of human frame?
Comparative anterior vs. posterior height of vertebral body and comparative anterior vs. posterior height of intervertebral disc
How does the vertebral column accommodate transmission?
Peripheral nerve communicates with central nerve system via the intervertebral foramen
What organs are specifically associated with the horizontal axis of the skull?
Eye and vestibular apparatus of the inner ear
How is the vertebral column involved in stabilization of visceral function?
Integrity of spinal column enhances appropriate nerve system control of viscera
When does embryonic disc form?
2nd wk in utero
When does gastrulation occur (3 layered embryo form)
3rd wk in utero
What are the 3 layers of embryo called?
Ectoderm, mesoderm, endoderm
Invagination of ectoderm along primitive streak gives rise to what embryonic structure?
Notochord
What is the name given to mesoderm that will give rise to vertebral column
Paraxial mesoderm
What does paraxial mesoderm give rise to that will form vertebral column
Somites
Areas of cellular differentiation formed within somite
Sclerotome
Myotome
Dermatome
Part of somite that gives rise to vertebral column
Sclerotome
Order of successive vertebral columns formed during development
Membranous, cartilaginous, skeletal/osseous
Migration of sclerotomes to surround notochord forms what developmental feature?
Perichordal blastema
Perichordal blastema gives rise to what processes?
Neural processes and costal processes
Name of artery between adjacent perichordal blastemae
Intersegmental artery