Esophagus, Stomach, And Intestines- Lecture 10/12/21 Flashcards

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1
Q

Mucosa

A

Made up of the epithelium, lamina propria, and muscularis mucosae

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2
Q

Layers of GI wall

A

Mucosa, sbmucosa, muscularis externa, adventitia

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3
Q

Esophagus epithelia

A

SSNKE

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4
Q

Muscular makeup of esophagus

A

Upper 1/3= skeletal
Middle 1/3= Skeletal and smooth
Lower 1/3= Smooth muscle

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5
Q

Esophageal submucosal glands

A

Often mixed serous and mucus, secretes mucus, bicarbonate, lysozyme, pepsinogen, EGF

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6
Q

Gastric epithelium

A

Simple columnar

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7
Q

Barrett esophagus:

A

Metaplastic to gastric or intestinal mucosa (chronic GERD)

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8
Q

Gastric glands proper

A

Parietal, zymogenic, and chief cells in mucosa

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9
Q

Parietal cells

A

Secrete HCl, cells with a lot of mitochondria, secrete intrinsic factor (B12 absorption)

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10
Q

Intracellular canaliculus

A

Increases surface area of parietal cells, increasing HCl prduction

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11
Q

Chief cells

A

Secrete pepsiogen and lipase

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12
Q

Components of the small intestine

A

Duodenum, jejunum, Ileum

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13
Q

Small intestine epithelium

A

Simple columnar with microvilli

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14
Q

Relative distribution of goblet cells

A

More prevalent later int he tract (more goblet cells in the ileum than duodenum

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15
Q

Plicae circulares

A

Submucosal core, increases surface area

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16
Q

Villi

A

Lamina propria core, increases surface area

17
Q

Paneth cells

A

Secrete lysozyme, and antimicrobial proteins

18
Q

Stem cells

A

Found in crypts, generate all 4 SI cells

19
Q

Types of SI cells (4)

A
  • Enterocyte
  • Goblet cell
  • enteroendocrine
  • Paneth