Cartilage And Bone - Lecture 9/15/21 Flashcards
Types of cartilage (3)
Hyaline
Elastic
Fibrocartilage
Hyaline cartilage
Translucent
Very hydrated, resists compression
Smooth
Located at all articulated joint surfaces
Elastic
Similar to hyaline but also contains elastic fibers
Where elastic cartilage is found
External ear, Eustachian tube, epiglottis
Fibrocartilage
Hydrates, but also contains collagen I so also high in tensile strength
Where fibrocartilage is found
Intervertebral discs, temporomandibular joints, pubic symphysis
Isogenous groups
Back to back D shaped cells, unique to cartilage
Territorial matrix
Very basophilic, close to cells so darker
Homogeneous inter territorial matrix ITM
Less basophilic, still shows up purple in between chondrocytes
Perichondrium
The edge of cartilage, contains chondroblasts, collagen II, “brick layer” cells
Appositional growth
From the pericardium, undergone by “bricklayer. Cells
Interstitial growth
Growth from within the cartilage matrix by chondrocytes
Osteoarthritis
Progressive wear and tear of the articulation cartilage, making it rough. Avascular and a neural so can’t fix it
Rheumatoid arthritis
Autoimmune disease that affects Synovium and cartilage
Aspects unique to fibrocartilage
Has no perichondrium, type I fibers present, has fibroblasts
Woven bone
Immature bone, disorderly arrangement of collagen
Lamellar bone
Mature bone, can be compact or spongy
Characteristics of Compact bone
Have heversion systems with concentric lemallae and osteocytes interconnected by processes within the lamellar
Periosteum
Outside of lamellar bone
Endosteum
Inside of lamellar bone
Canaliculi
Tunnels through the bone that allow osteocytes to connect with each other
Other names for spongy bone
Cancellous or trabecular
Woven bone structure
Inner calcified cartilage, irregular bone placed by osteoblasts on the outside
Osteon
Contains the Haversian canal, surrounded by concentric lamellae
External circumferential lemellae
Surrounds the entirety of the bone, inside the periosteum
Volkman’s canal
Channel connecting the Haversian canals, not surrounded by concentric lamellae
Inner circumferential lamellae
Separetes the compact from spongy
Trebecula
A section of spongy bone, contains bone lamellae but no haversion systems
Osteogenic cells
Osteoblasts or osteocytes, Mesenchymal derivative
Osteoclasts
Breaks bone down, derived from the marrow acidophilic
Howship’s lacunae
Burrow that osteoclasts make in the bone when breaking it down
Osteoporosis
When bone degradation is greater than bone formation, more common in post menopausal women because physiologic estrogen inhibits bone resorption
Osteogenesis imperfecta
Brittle bone disease-> mutations in type one collagen