ENTEROBACTERIACEAE - KLEBSIELLA Flashcards
Klebsiella has how many species?
4
Among the species of Klebsiella, which is pathogenic for animals?
Klebsiella pneumoniae
Klebsiella pneumoniae is an opportunistic invader of ?
- Reproductive tract of mares
- Bovine mammary gland
- Urinary tract of bitches
What type of infection does Klebsiella normally induce?
Nosocomial infection in human and animal patients - due to its ability to acquire multiple antibiotic resistance and to spread in hospital environments.
What is the other name of Kelbsiella pneumoiae?
Friedlander’s bacillus
Describe the morphology of Klebsiella pneumoniae.
Gram negative, non-sporeforming, heavily encapsulated rod 0.3 to 1.0 um x 0.6 to 6.0 um, non-flagellated
Describe the colonies of K. pneumoniae.
Colonies are moist, spreading, glistening and very viscid
Capsule production of K. pneumoniae is enhanced by ?
Carbohydrate
** Carbohydrate medium
K. pneumoniae is oxidase positive. True or False?
False
Classify K. pneumonaie according to its oxygen requirement.
Facultative anaerobe
K. pneumoniae uses tartrate and malonate. True or False?
True
K. pneumoniae produces H2S. True or False?
True
K. pneumoniae produces urease. True or False?
True
K. pneuomoniae is positive in MR test but negative in VP test. True or False?
False, other way around
Lactose positivity of K. pneuomoniae is on the genome or on the plasmid?
Plasmid
Give the antigens of K. pneumoniae and its quantities.
- 82 capsular types
- 11 O antigens
- K - for serologic typing only
It is a heat-stable polysaccharide composed of one-charged monosaccharide usually glucuronic acid and two or more sugars galactose, fucose, mannose, D-glucose or L-rhamnose.
K antigen
K. pneumoniae is _____ commensal but also can be found in the environmet.
intestinal
What is the important predisposing factor of K. pneumoniae?
Usage of antibiotics
Invasive strains of K. pneumoniae are resistant to ?
Serum bactericidal factors
Mares carry the organism, as normal flora, in ? (Hint: body parts)
- Vestibule
- Urethra
- Clitoris
Opportunistic invasion of the organism result in ?
- Vaginal discharge
- Metritis
- Infertility
- Abortion
Stallion can transmit from mare to mare and they can also be a reservoir of infection. True or False?
False, usually not reservoir
The organism is an important component of etiology of ____ ____ in cattle.
coliform mastitis
Give the diseases induced by K. pneuomoniae infection.
- Vaginal discharge, metritis, infertility, abortion
- Acute or peracute form of mastitis
- Hyperemia; edema and swelling of the udder and milk secretion reduced and altered to serous fluid
- High fever initially which may subside in a few hours if animal develops often fatal endotoxic shock
- Mastitis in sows and pneumonia in goats
What are the forms of immunity against K. pneuomoniae ?
- Little known about protective immunity to K pneumoniae
- Only strains resistant to serum bactericidal factors invasive
- Serum antibody measured by capsular swelling technique
What are the diagnostic methods for the mentioned organism?
- Heavily encapsulated appearance I smears
- Mucoid colonies on agar
- Tampons left in place for 10 minutes more effective in detecting uterine infections in mares than simple swabbing
K. pneumoniae is resistant to what antibiotics?
- Ampicillin
- Carbenicillin
K. pneumoniae is maybe susceptible to antimicrobials against _______.
E. coli
____ is effectve in treament of canine urinary tract infections.
Cephalexin
