HEMOPHILUS Flashcards
Genus Haemophilus requires what factors?
- Hennin (X)
- Niacinamide adenine nucleotide (V)
** either or both growth factors
H. pleuropneumonia causes what disease in swine?
Contagious pleuropneumonia
H. pleuropneumonia has no capsule. True or False?
False. capsulated virulent strain
Genus Haemophilus is in cocco-bacilli shaped. True or False?
True
Describe H. pleuropneumonia according to its oxygen requirement.
Facultatively anaerobic and requires atmosphere with increased CO2
H. pleuropneumonia is non-fastidious. True or False?
False, it grows rapidly on BAP and enriched media
H. pleuropneumonia has A-hemolysin. True or False?
False, B-hemolysin; can be enhanced by S. aureus
Describe the colonies of H. pleuropneumonia.
Colonies 1-2 mm, mucoid and iridescen
Antigens serotyping on H. pleuropneumonia is based on ____ antigen of _____ materials.
surface; capsular
H. pleuropneumonia is transmitted via ?
respiratory route
What are the predisposing factors in H. pleuropneumonia infection?
- Inclement weather
- Poor ventilation
- Intercurrent infection
Pigs are most susceptible at what age?
3 months old (weaning)
______ believed to play an important role in formation of thrombi (blood clot attached to wall) and interlobular edema (edema in lungs) resulting from damage of vasculature.
Endotoxin
Describe the lesions induced by H. pleuropneumonia.
Lesions consists of exudative and proliferative desquamative bronchopneumonia with fibrous pleuritis.
What are the immunization methods against H. pleuropneumonia?
- Develops after recovery from infection
- Passive immunity (mother to offspring via colostrum, placenta, transfusion, serum etc.)
What are the diagnostic methods for H. pleuropneumonia?
- Isolation on BAP
- Requirement for V factor
- Presence of B-hemolysin
Give the main difference of H. pleuropneumonia and H. parasuis.
H. parasuis is not dependent on X factor (requires V factor)
H. parasuis causes what clinical disease in swine?
Respiratory tract disease and polyserositis (Glasser’s disease; inflammation in serous surfaces) in swine characterized by fibrinous inflammation of serous surfaces
H. parasuis causes _____ phenomenon in CAMP test.
satellitism
_____ _____ virus predisposes swine to H. parasuis.
Swine influenza
H. paragallinarum causes what disease in fowls?
Fowl coryza
Between H. pleuropneumonia. H. parasuis, and H. paragallinarum, which is secondary viral invader?
H. paragallinarum - associated with viral infection (maybe also H. parasuis)
Describe H. paragallinarum according to its O2 requiremnt.
Facultative anaerobe; grows best at 10% CO2 (carboxyphilic)
This specie of Haemophilus requires V but not the X factor.
H. paragallinarum
Transmission of H. paragallinarum is via ?
- Respiratory route
- Contaminated drinking water
H. paragallinarum infection becomes a severe disease when ?
In presence of viral or mycoplasma infection → synergistic effect
What are the antigens present in H. gallinarum?
1. Heat labile surface antigens
2. Hemagglutinating antigen (for serotyping) - typing system known as HA-L method- antigen on outer surface of bacterial cell (only in encapsulated organism
*antibody should be present for heme to not be aggluntinated
H. somnus causes what clinical disease in swine?
Infectious thromboembolic meningoencephalitis (TEME)
H. somnus is an official Haemophilus spp. True or False?
False
H. somnus is dependent on V factor. True or False?
False, not dependent on the two factors but rather on CO2
H. somnus can be found in?
Nasal and genital cavities of cattle
H. somnus can be predisposed via ?
- Shipping
- Climate change
- Regrouping
Describe the lesions induced by H. somnus.
Fibrinous meningitis