Endocrine System Live Lecture Flashcards
Which endocrine gland is shown in the image?
Pancreas
The pancreas, unlike the adrenal glands, is not under direct control of the ______
The pancreas, unlike the adrenal glands, is not under direct control of the pituitary gland
“self-regulated”
The pancreas is both an _____ and an ______ gland
Exocrine and endocrine gland
What is the difference in endocrine and exocrine glands?
Endocrine- produce hormones that enter the circulatory system
Exocrine- produce secretions that go to an epithelial surface
The head of the pancreas is tucked into the bend of the ______ of the small intestine, and is attached to the __________wall
The head of the pancreas is tucked into the bend of the duodenum of the small intestine and is attached to the posterior abdominal wall
The clusters of endocrine tissue embedded within the exocrine tissue of the pancreas are called:
Islets of Langerhans
The alpha cell of the pacreatic islet secretes:
Alpha cells secrete glucagon
The beta cells of the pancreas secrete:
Insulin
The Delta cell of the pancreas secretes:
Somatostatin
What does glucagon do?
What produces glucagon?
- Functions:
- Stimulates glucose synthesis
- Elevates blood glucose
- Mobilizes lipid reserves
- Produced by:
- Alpha cells of the pancreas
What is the function of insulin?
What is it produced by?
- Functions
- Stimulates lipid and glycogen synthesis and storage
- Stimulates glucose uptake by cells
- Decreases blood glucose levels
- Produced by:
- Beta Cells of the pancreas
What is the function of somatostatin?
What is it produced by?
- Function:
- Inhibits secretion of glucagon and insulin
- Produced by Delta Cells of the pancreas
What is diabetes mellitus?
Inability to produce or use insulin
- Elevation of blood glucose levels (hyperglycemia)
- Excretion of glucose in the urine
- Don’t make enough insulin = cells don’t take up glucose
- Cells don’t respond to insulin = don’t take up glucose
What is type I diabetes caused by?
Autoimmune:
- immune system destroys beta cells in the pancreas
- can’t produce insulin
Insulin-dependent diabetes
What is Type II diabetes?
Combination of insulin-resistance and insulin-secretory defects
- Target cells become less sensitive to insulin
- due to downregulation of receptors
- Non-insulin-dependent diabetes
- Correlates with age and obesity