endocrine system/hormones Flashcards
what are the three types of stimuli that trigger endocrine glands to secrete their hormones?
- hormonal
- humoral
- neural
what is a hormonal stimulus?
one hormone stimulates the secretion of another
what is a humoral stimulus?
changes in ion or nutrient blood levels eg. glucose
what is a neural stimulus?
signals from the nervous system
what are the two basic types of hormones?
steroid and amino acid-based hormones
are steroid hormones lipid soluble or insoluble?
lipid soluble
are amino acid-based hormones lipid soluble or insoluble?
lipid insoluble
do steroid hormones bind to receptors on the membrane or inside the cell?
intracellular receptors
do amino acid-based hormones bind to receptors on the membrane or inside the cell?
bind to receptors embedded in plasma membrane
what are steroid hormones made from?
cholesterol
why is the hypothalamus classified as an neuroendocrine organ?
has both neural and endocrine function
what is antidiuretic hormone (ADH) secreted by?
posterior pituitary
what is oxytocin secreted by?
posterior pituitary
what is prolactin (PRL) secreted by?
anterior pituitary
what is follicle stimulating hormone (FSH) secreted by?
anterior pituitary
what is luteinising hormone (LH) secreted by?
anterior pituitary
what is insulin secreted by?
beta cells
what is glucagon secreted by?
alpha cells
what is growth hormone (GH) secreted by?
anterior pituitary
what is adrenocorticotropic hormone (ACTH) secreted by?
anterior pituitary
what is cortisol/cortisone secreted by?
adrenal glands
what is aldosterone secreted by?
adrenal glands
what is adrenaline/noradrenaline secreted by?
adrenal glands
what is erythropoietin (EPO) secreted by?
kidneys
what is thyroid-stimulating (TSH) secreted by?
anterior pituitary
what is thyroid hormone (TH) secreted by?
anterior pituitary
what is the parathyroid hormone (PTH) secreted by?
anterior pituitary
what is the stimulus for the secretion of Antidiuretic hormone (ADH)?
when blood Na+ levels increase above normal, and/or blood volume/pressure decreases
what is the stimulus for the secretion of oxytocin?
stretching of uterus during labour, suckling of infant when breastfeeding
what is the stimulus for the secretion of prolactin?
prolactin-inhibiting hormone (PIH)
what is the stimulus for the secretion of insulin?
blood glucose levels increase
what is the stimulus for the secretion of glucagon?
blood glucose levels decreases
what is the stimulus for the secretion of growth hormone?
growth hormone-releasing/inhibiting hormones
what is the stimulus for the secretion of adrenocorticotropic hormone (ACTH)?
corticotrophin-releasing hormone
what is the stimulus for the secretion of cortisol and cortisone?
adrenocorticotropic hormone (ACTH)
what is the stimulus for the secretion of aldosterone?
increases in K+ levels
what is the stimulus for the secretion of adrenaline/noradrenaline?
sympathetic division
what is the stimulus for the secretion of erythropoietin (EPO)?
when blood oxygen levels drop below normal range
what is the stimulus for the secretion of thyroid-stimulating hormone?
thyroid-releasing hormone (TRH)
what is the stimulus for the secretion of thyroid hormone?
thyroid-stimulating hormone (TSH)
what is the stimulus for the secretion of calcitonin?
blood Ca2+ levels increase above normal range
what is the stimulus for the secretion of parathyroid hormone?
blood Ca2+ levels decrease below normal
what is the stimulus for the secretion of oestrogen?
FSH and LH
what is the stimulus for the secretion of progesterone?
LH
what is the stimulus for the secretion of testosterone?
LH
what are the target organ/s cells of ADH?
kidneys
what are the target organ/s/ cells of oxytocin?
uterus, mammary glands
what are the target organ/s/ cells of PRL?
mammary glands
what are the target organ/s/ cells of FSH?
ovaries
what are the target organ/s/ cells of LH?
ovaries/testes
what are the target organ/s/ cells of insulin?
kidneys
what are the target organ/s/ cells of glucagon?
kidneys
what are the target organ/s/ cells of ACTH?
adrenal cortex
what are the target organ/s/ cells of growth hormone?
liver, skeletal muscles and bones
what are the target organ/s cells of aldosterone?
kidneys
what are the target organ/s/ cells of EPO?
bone marrow
what are the target organ/s/ cells of TSH?
thyroid gland
what are the target organ/s/ cells of TH?
virtually every cell
what are the target organ/s/ cells of calcitonin?
bone cells
what are the target organ/s cells of PTH?
bone cells
what are the target organ/s/ cells of oestrogen?
ovaries
what are the target organ/s/ cells of progesterone?
ovaries
what are the target organ/s/ cells of testosterone?
testes
what is the main action/s of ADH?
- decreases urine output
- vasoconstriction of arterioles which helps increase blood pressure
what is the main action/s of oxytocin?
- stimulates uterus contractions
- ejection of milk
what is the main action/s of PRL?
stimulates milk production
what is the main action/s of FSH?
- ovum production
- secretion of oestrogen
- regulates sperm
what is the main action/s of LH?
- ovulation
- production and secretion of pregesterone (mainly), oestrogen and testosterone
what is the main action/s of insulin?
decrease blood glucose levels
what is the main action/s of glucagon?
increase blood glucose levels
what is the main action/s of growth hormone?
promotes growth of body tissues
what is the main action/s of ACTH?
stimulates adrenal cortex to secrete cortisol and cortisone
what is the main action/s of cortisol/cortisone?
- maintain good glucose levels
- resist stress
- potent anti-inflammatory agents
what is the main action/s of aldosterone?
maintain blood K+ and Na+ levels
what is the main action/s of adrenaline/noradrenaline?
prolong fight-or-flight responses
what is the main action/s of EPO?
stimulates production of red blood cells
what is the main action/s of TSH?
stimulates thyroid gland to secrete thyroid hormones T3 (triiodothyronine) and T4 (thyroxine)
what is the main action/s of TH?
- increases BMR and body temp
- promotes growth of muscle/bone
- promotes nervous system development
what is the main action/s of calcitonin?
decreases blood Ca2+ levels
what is the main action/s of PTH?
increases blood Ca2+ levels
what is the main action/s of oestrogen?
- regulates menstrual cycle
- development of reproductive organs
- secondary sex characteristics
what is the main action/s of progesterone?
- prepares uterus for birth
- maintains pregnancy
- regulates menstrual cycle
what is the main action/s of testosterone?
stimulates sperm production
what do parafollicular cells produce and secrete?
hormone calcitonin
what contains the cells that produce and secrete EPO?
kidneys
what is the outer adrenal cortex responsible for producing and secreting?
cortisol, cortisone and aldosterone
what is the inner adrenal medulla responsible for producing and secreting?
adrenaline and noradrenaline