Endocrine Formative Flashcards
Presentation of dangerous Carbimazole side effect?
Sore throat/ fever/ mouth ulcers
suggests agranulocytosis/ WBC suppression
Drug treatment for Phaeochromocytoma? (2)
Alpha blocker FIRST,
then beta blocker
Diagnostic test for Acromegaly
Oral GTT
How does an Addisonian crisis present? (4)
Vomiting, Diarrhoea, HypOtension, Tachycardia
Treatment of Addisonian crisis? (2)
IV Saline
Hydrocortisone
All pituitary tests low, but prolactin slightly raised. Diagnosis?
Non-functioning adenoma
blocks dopamine production hence prolactin
Diffusely dark radioiodine thyroid scan?
Grave’s disease
How does Thyroiditis present on radioiodine thyroid scan?
Diffusely light
Dark spot on radioiodine scan?
Toxic nodule
Several dark spots on radioiodine scan?
Toxic multinodular goitre
Test for Conn syndrome?
Aldosterone: Renin ratio
What does cabergoline do?
Lowers prolactin
Dopamine receptor agonist
BIG MANLY MEN TOSS CABERS AND HAVE LOW PROLACTIN
Which organs are affected in MEN1? (3)
Pituitary
Parathyroid
Pancreas
3Ps, MEN always think with their PPs 1st
When in a menstrual cycle does ovulation occur?
14 days before next period (ie day 14 of 28 day period)
What drug class puts DM patients most at risk of hypoglycaemia?
Sulphonylurea
eg Glicazide, Glibenclamide, Glimeparide