Endocrine Formative Flashcards

1
Q

Presentation of dangerous Carbimazole side effect?

A

Sore throat/ fever/ mouth ulcers

suggests agranulocytosis/ WBC suppression

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2
Q

Drug treatment for Phaeochromocytoma? (2)

A

Alpha blocker FIRST,

then beta blocker

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3
Q

Diagnostic test for Acromegaly

A

Oral GTT

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4
Q

How does an Addisonian crisis present? (4)

A

Vomiting, Diarrhoea, HypOtension, Tachycardia

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5
Q

Treatment of Addisonian crisis? (2)

A

IV Saline

Hydrocortisone

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6
Q

All pituitary tests low, but prolactin slightly raised. Diagnosis?

A

Non-functioning adenoma

blocks dopamine production hence prolactin

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7
Q

Diffusely dark radioiodine thyroid scan?

A

Grave’s disease

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8
Q

How does Thyroiditis present on radioiodine thyroid scan?

A

Diffusely light

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9
Q

Dark spot on radioiodine scan?

A

Toxic nodule

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10
Q

Several dark spots on radioiodine scan?

A

Toxic multinodular goitre

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11
Q

Test for Conn syndrome?

A

Aldosterone: Renin ratio

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12
Q

What does cabergoline do?

A

Lowers prolactin

Dopamine receptor agonist

BIG MANLY MEN TOSS CABERS AND HAVE LOW PROLACTIN

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13
Q

Which organs are affected in MEN1? (3)

A

Pituitary
Parathyroid
Pancreas

3Ps, MEN always think with their PPs 1st

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14
Q

When in a menstrual cycle does ovulation occur?

A

14 days before next period (ie day 14 of 28 day period)

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15
Q

What drug class puts DM patients most at risk of hypoglycaemia?

A

Sulphonylurea

eg Glicazide, Glibenclamide, Glimeparide

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16
Q

What does Carbimazole do?

A

Prevents thyroid making thyroid hormone

17
Q

What to remember with with Carbimazole?

A

Agranulocytosis & WBC suppression!

Watch out for sore throat/mouth ulcers/fever

18
Q

How does Thyroiditis present on radioiodine uptake scan?

A

Diffusely light

19
Q

How does Grave’s disease present on radioiodine uptake scan?

A

Diffusely dark

It’s completely serious, grave (thanks GHB)