CLASP Sepsis Flashcards by Shagma Botome

Q

Define Colonisation?

A

Microbe found in human body, without inflammatory response

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Q

Define Infection?

A

Inflammation due to presence of microbe

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Q

Define Bacteraemia?

A

Presence of viable bacteria in blood

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Q

Define Sepsis?

A

Dysregulated host response to infection

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Q

Define Septic Shock? (3)

A

Sepsis (dysregulated host response to infection) AND
Persistent Hypotension AND
Lactate >2mmol/l

(despite resus)

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Q

Define the qSOFA criteria

A

RR>22
sBP < 100mmHg
GCS <14 (AMS)

1 point for each

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Q

What is the predicted mortality of a patient with a qSOFA score of 2?

A

> 10% will die

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Q

At what NEWS score should we think sepsis?

A

5

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Q

Complete the 4 Cs:
\_\_\_\_\_\_\_\_\_\_\_
Cephalosporins
Clindamycin
Ciprofloxacin

A

Co-Amoxiclav
Cephalosporins
Clindamycin
Ciprofloxacin

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Q

Complete the 4 Cs:
Co-Amoxiclav
\_\_\_\_\_\_\_\_\_\_\_
Clindamycin
Ciprofloxacin

A

Co-Amoxiclav
Cephalosporins
Clindamycin
Ciprofloxacin

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Q

Complete the 4 Cs:
Co-Amoxiclav
Cephalosporins
\_\_\_\_\_\_\_\_\_\_\_\_
Ciprofloxacin

A

Co-Amoxiclav
Cephalosporins
Clindamycin
Ciprofloxacin

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Q

Complete the 4 Cs:
Co-Amoxiclav
Cephalosporins
Clindamycin
\_\_\_\_\_\_\_\_\_\_\_

A

Co-Amoxiclav
Cephalosporins
Clindamycin
Ciprofloxacin

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Q

Name the 4 Cs antibiotics

A

Co-Amoxiclav
Cephalosporins
Clindamycin
Ciprofloxacin

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Q

Criteria for diagnosing endocarditis?

A

Duke criteria

Dukes’ criteria is for staging bowel cancer, idiotically

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Q

What is the Mean Inhibitory Concentration (MIC) of an antibiotic?

A

Concentration required to kill 99.9% of bacteria in 18-24hrs

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Q

How is Bacillus Cereus managed?

A

Supportively

Q

What type of haemolysis is seen in Enterococcus Faecalis?

A

Gamma haemolysis /no haemolysis

Q

Is Staph Aureus coagulase positive or negative?

A

Positive (kind fucks up ya blood)

Q

Common GI drug that increases the change of developing C. Diff infection?

A

PPI

Q

Name the typical infective endocarditis organisms (3)

A

Staph
Strep
HACEK

Q

Coverage of Vancomycin?

A

Gram Positive only

POS> Piece of Shit> Wank> Vanc

Q

Mortality of Septic Shock?

A

> 40%

Q

Treat simple E. Coli infection?

A

Supportively
as high risk of developing resistance

(obvs treat if they’re fucking it with HUS)

Q

Treatment for Extended-Spectrum Beta-Lactamase (ESBL) producing microorganisms?

A

Carbapenems