endocrine Flashcards
signs of hypothyroidism at birth
lethargy growth deceleration large fontanels bradycardia hypotonia macroglosia
lethargy growth deceleration large fontanels bradycardia hypotonia macroglosia in newborn
signs of hypothyroidism
signs of hypothyroidism in older kids
weakness/muscle fatigue poor growth gold intolerance constipation weight gain poor motor coordination dry skin puffy eyes thinning hair and brittle nails alopecia deep tendon reflex
weakness/muscle fatigue poor growth gold intolerance constipation weight gain poor motor coordination dry skin puffy eyes thinning hair and brittle nails alopecia deep tendon reflex
hypothyroidism in older kids
work up for short stature
bone age insulin growth factor karyotype thyroid function TTG
work up for hypothyroidism
TSH
T4 and free T4 are both low or low normal
increased liver enzymes
T3 is not a good test for hypothyroidism
constitutional growth delay signs
Normal size at birth, followed by a decrease in both height and weight velocity in the first years of life
Normal velocity following lower percentile
Height and weight equally affected
Attain normal adult height
Constitutional growth delay vs familial short stature
constitutional growth delay there is a delay in bone age as well as puberty but there is a difference in the staging between bone age and puberty.
normal adult height
Familial short stature has normal puberty
Bone age is the same as chronological age
Final height is decreased
abnormal growth in kids
growth that falls off curve 2 SD and is not between mid parental height
growth failure
4cm per year
being at the 5th %ile or lower
impaired glucose tolerance
fasting blood glucose between 100 and 125
Diagnostic findings with dm1
fasting blood sugar 126 on 2 separate occasions
random sugar of greater than 200 with polyuria/polydypsia
what is somogyi effect
early am hyperglycemia due to nocturnal hypoglycemia
what is dawn phenomenon
tissue desensitized to insulin nocturnally resulting in elevated blood sugar through the night and elevated at 7 am
how to tx dawn phenomenon
add or inc the dose of hs insulin