endocrine Flashcards

1
Q

signs of hypothyroidism at birth

A
lethargy
growth deceleration
large fontanels
bradycardia
hypotonia
macroglosia
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2
Q
lethargy
growth deceleration
large fontanels
bradycardia
hypotonia
macroglosia
in newborn
A

signs of hypothyroidism

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3
Q

signs of hypothyroidism in older kids

A
weakness/muscle fatigue
poor growth
gold intolerance
constipation
weight gain
poor motor coordination
dry skin
puffy eyes
thinning hair and brittle nails
alopecia
deep tendon reflex
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4
Q
weakness/muscle fatigue
poor growth
gold intolerance
constipation
weight gain
poor motor coordination
dry skin
puffy eyes
thinning hair and brittle nails
alopecia
deep tendon reflex
A

hypothyroidism in older kids

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5
Q

work up for short stature

A
bone age 
insulin growth factor
karyotype
thyroid function
TTG
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6
Q

work up for hypothyroidism

A

TSH
T4 and free T4 are both low or low normal
increased liver enzymes
T3 is not a good test for hypothyroidism

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7
Q

constitutional growth delay signs

A

Normal size at birth, followed by a decrease in both height and weight velocity in the first years of life
Normal velocity following lower percentile
Height and weight equally affected
Attain normal adult height

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8
Q

Constitutional growth delay vs familial short stature

A

constitutional growth delay there is a delay in bone age as well as puberty but there is a difference in the staging between bone age and puberty.
normal adult height
Familial short stature has normal puberty
Bone age is the same as chronological age
Final height is decreased

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9
Q

abnormal growth in kids

A

growth that falls off curve 2 SD and is not between mid parental height

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10
Q

growth failure

A

4cm per year

being at the 5th %ile or lower

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11
Q

impaired glucose tolerance

A

fasting blood glucose between 100 and 125

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12
Q

Diagnostic findings with dm1

A

fasting blood sugar 126 on 2 separate occasions

random sugar of greater than 200 with polyuria/polydypsia

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13
Q

what is somogyi effect

A

early am hyperglycemia due to nocturnal hypoglycemia

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14
Q

what is dawn phenomenon

A

tissue desensitized to insulin nocturnally resulting in elevated blood sugar through the night and elevated at 7 am

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15
Q

how to tx dawn phenomenon

A

add or inc the dose of hs insulin

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16
Q

dm2 tx

A

metformin 500 mg tid

17
Q

how to tx hyperthyroidism

A

propnaolol for symptoms

methimazole

18
Q

heat inolerance, tachy cardia and lid lag

A

think hyperthyroidism

19
Q

CAH tx

A

glucocorticoid administration

20
Q

adrenal insufficiency (addison’s disease) symptoms

A

Fatigue, hyperpigmented knuckles and joints, salt craving

21
Q

Addison’s disease treatment

A

hormone replacement

22
Q

Addison’s disease workup

A

ACTH stim test to see cortisol and aldosterone production

23
Q

Addisonian crisis symptoms

A

back pain. n/v/d, low bp, LOC