Endocarditis Flashcards
risk factors
calcification in elderly
congenital heart disease
rheumatic fever
IV drugs
prosthetic heart valve
cause in PWID
S.aureus
cause after dental surgery
S.viridans
cause in prosthetic valves
S.epidermidis
atypical causative organisms
Coxiella burnetti
gram negatives
HACEK Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, Kingella
PWID valve affected
tricuspid (R sided)
most common valve affected
mitral (L sided)
pathology
- Bacteraemia organisms settle in fibrin or platelet thrombi becoming thrombotic vegetations
- These are friable and break off causing septic emboli or haemorrhage.
- Can be fatal
classification
dukes
dukes major
2 separate positive blood cultures Endocardial involvement
ECHO findings
dukes minor
Fever >38 C
IV drug user or predisposing heart condition, and Immunological phenomena (eg Osler’s nodes, Roth’s spots)
Vascular phenomena, e.g. mycolytic aneurysm/Janeway L’s
CF
Fever
Roth spots
Osler nodes
Murmur (new)
Janeway lesions
Anaemia
splinter Nail haemorrhage
Emboli
investigations
Blood - 3 separate places and 3 cultures
Blood for anaemia
Urinalysis
CXR ECHO - trans thoracic or transesophageal for vegetations
treatment for prosthetic valve or suspected MRSA
epidermidis
vancomycin IV and Gentamicin IV and delayed rifampicin PO
valve replacement may be required