aspects of CVD risk Flashcards

1
Q

what does ASSIGN score allow

A

one to measure risk of developing cardiovascular disease.

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2
Q

what does QRISK2 score allow

A

to determine the risk of a cardiovascular event in the next 10 years.

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3
Q

what does ABCD2 score do

A

used to identify the risk of stroke in patients who have had a suspected TIA.

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4
Q

what does the DRAGON score predict

A

predicts the 3-month outcome in ischaemic stroke patients receiving tissue plasminogen activator (tPA).

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5
Q

what do all CVD risk factors do

A

cause stress on the vessel wall

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6
Q

what is a modifiable CV risk factor

A

total cholesterol

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7
Q

what do statins reduce

A

total cholesterol and LDL cholesterol

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8
Q

what are other actions of statins

A

improvement of endothelial dysfunction

increased nitric oxide bioavailability

antioxidant properties

inhibition of inflammatory responses

stabilisation of atherosclerotic plaques

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9
Q

what does hypertension treatment reduce

A

ischaemic heart disease, stroke and mortality

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10
Q

what is the metabolic syndrome

A

cluster of conditions that occur together that inc your risk of heart disease and stroke etc

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11
Q

name metabolic syndrome factors

A

abdominal obesity, triG, HDL, blood pressure and fasting glucose

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12
Q

what are xanthomas

A

lipids accumulate in large foam cells within the skin

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13
Q

xanthelasma

A

xanthoma of the eyelids associated with hyperlipidaemia

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14
Q

where are tendon xanthomas

A

extensor tendons of fingers, patella, elbows, Achilles tendon

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15
Q

what are tendon xanthomas associated with

A

hypercholestraemia

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16
Q

what do Cerebrotendinous xanthomatosis have high levels of

A

plant sterols and cholesterol precursors

17
Q

where are tuberous xanthomas found

A

over joints

18
Q

what are tuberous xanthomas seen in

A

familial or acquired hypertriglyceridaemias

19
Q

what are tuberous xanthomas seen with

A

biliary cirrhosis

20
Q

where are eruptive xanthomas seen

A

bum, posterior thighs and body folds

inc in triglyceride levels