Endicrinology Flashcards

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1
Q

what is a hormone?

A

chemical signal secreted by specialised endocrine cells directly into the blood to exert an effect on distant target cells.

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2
Q

what are autocrines?

A

effect on itself

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3
Q

what are paracrines?

A

same local environment

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4
Q

what is a humoural stimulus?

A

caused by altered levels of certain critical ions or nutrients

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5
Q

what is a neural stimulus?

A

hormone release caused by neural input

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6
Q

what is a hormonal stimulus?

A

hormone release caused by another hormone

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7
Q

what does the pineal gland do?

A

secretes melatonin at night which makes you drowsy

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8
Q

where does the hypothalamus receive input from?

A
  • higher brain centers

- also receive input from visceral and somatic sense via brain stem.

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9
Q

what does the posterior lobe secrete?

A
  • secretes oxytocin and vasopressin

- hormones are secreted from paraventricular nucleus and supreoptic nerve.

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10
Q

how do signals in the hypothalmic nuclei travel to the anterior pituitary?

A
  • neroendocrine signals such as TRH and GnRH are released.
  • travel down portal vein
  • act on specific cells in anterior pituitary to release hormone such as TSH, PRL, LH, FSH
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11
Q

what does GnRH secrete?

A

LH and FSH

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12
Q

what is the role of LH in females?

A

-acts on the ovarian follicle and induces ovulation

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13
Q

what is the role of FSH in females?

A

causes development on the ovarian follicle and stimulates secretion of oestradiol and progesterone.

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14
Q

what is the role of LH in males?

A

acts on testes to produce testosterone

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15
Q

What is the role of FSH in males?

A

acts on testes to maintain spermatogenesis

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16
Q

how does the negative feedback of TSH work?

A
  • Increased T4 and T3 stimulates anterior lobe of pituitary gland to reduce TSH secretion
  • T4 and T3 reduces in circulation ,removing the block on TSH secretion.
17
Q

what does ACTH hormone secretion result in?

A

cortisol

18
Q

which hormone released from posterior pituitary increase water retention?

A

ADH

19
Q

When is Oxytocin released?

A
  • when giving birth
  • socialisation
  • orgasm
20
Q

what is the function of parathyroid hormone (PTH)?

A

PTH retains calcium

21
Q

ACTH has an effect on the cortex and releases corticosteroids. What are mineralcorticoids released for?

A

increases NA+ retention by kidney and thus H20

maintains BP and blood volume.

22
Q

what are glucocorticoids used for?

A
  • increases metabolism of fats

- increases blood glucose levels through gluconeogenesis

23
Q

what is ACTH secretion regulated by?

A

CRH

Negative feedback

24
Q

what are androgens used for?

A

precursors to testosterone