Effects of excess alcohol Flashcards
1
Q
At what zone does alcohol metabolism take place?
A
Zone 3
2
Q
Explain fatty changes to the liver
A
- no liver damage seen
- fat disappears on stopping alcohol
- steatosis seen
3
Q
What causes fatty liver to become cirrhosis?
A
- collagen laid down around central hepatic veins
4
Q
Alcohol affects ____ cells, transforming them into collagen producing myofibroblasts
A
- stellate cells
5
Q
What is the limit of alcohol units per week and over how many days?
A
- max 14 units/week
- over 3 days
6
Q
Give some examples of acute affects of excess alcohol
A
- oesophagitis
- gastritis
- acute pancreatitis
7
Q
Give some examples of chronic affects of excess alcohol?
A
- hypertension
- cardiomyopathy
- MI
- Liver cirrhosis
8
Q
What are the results of foetal alcohol syndrome?
A
- growth deficiency
- mental retardation
- learning difficulties
9
Q
What are symptoms of chronic liver disease?
A
- stigmata: spiders
- encephalopathy
- prolonged prothrombin time
- hypoalbuminaemia
10
Q
What are symptoms of portal hypertension?
A
- caput medusa
- hypersplenism
- thrombocytopenia
11
Q
What drug may be used in the short term for alcohol related mortality rates?
A
- prednisolone
12
Q
What is the scoring system for cirrhosis?
A
- Childs- Turcotte-Pugh score
