Drug treatments

Question 1

Name a PPI

Answer 1

• Omeprazole

- lansoprazole

Question 2

How do PPI work?

Answer 2

• inhibition of gastric gland parietal cell H+/K+ ATPase

Question 3

What are PPIs used for?

Answer 3

• treatment of peptic ulcers
• Dyspepsia and GORD
• H.pylori infections

Question 4

Name a histamine (H2) Receptor antagonist

Answer 4

• ranitidine

Question 5

How do H2 receptor antagonists work?

Answer 5

• competitive antagonist of H2 receptor on basolateral of parietal cell

Question 6

What are H2 receptor antagonists used for?

Answer 6

• prevention and treatment of peptic ulcers

- dyspepsia and GORD

Question 7

Name a alginate and anatacid

Answer 7

• gaviscon

- peptac

Question 8

How do anatcids work

Answer 8

• act as buffers rasing the pH of gastric juices

Question 9

What are antacids used for?

Answer 9

• treatment of dyspepsia and GORD

Question 10

Name an antimuscarinic

Answer 10

• hyoscine butylbromide

Question 11

How do antimuscarinics work

Answer 11

• oppose a parasympathic stimulation

Question 12

What are antimuscarinics used for

Answer 12

• treatment of the smooth muscle spasms associated with IBS

Question 13

Name an antimotility drug

Answer 13

• loperamide

Question 14

How do antimotility drugs work

Answer 14

• increase tone and rhythmic contractions

Question 15

What are antimotility drugs used for?

Answer 15

• diarrhoea symptoms

Question 16

Name a aminosalicylates drug

Answer 16

• mesalazine

Question 17

How do Aminosalicylates work?

Answer 17

• anti-inflammaotry

- immunesuppression effect

Question 18

What are aminosalicylates used for?

Answer 18

• treatment of ulcerative colitis

- rheumatoid arthitis

Question 19

Name a bulk forming laxative?

Answer 19

• ispagula husk

Question 20

Name an osmotic laxative

Answer 20

• lactulose

Question 21

How do laxatives work?

Answer 21

• pull water into the lumen to reduce constipation

Question 22

Name a antiemetic dopamine D2 receptor antagonist

Answer 22

• domperidone

Question 23

What are antiemetic dopamine D2 receptor antagonists used for?

Answer 23

• treatment of nausea and vomiting

- treatment of GORD

Question 24

Name an antiemetic Histamine H1 receptor antagonist

Answer 24

• cyclizine

Question 25

Name an antiemetic 5-HT3 receptor antagonist

Answer 25

• Ondansetron