drugz Flashcards

CA06-07

1
Q

name 3 types of drugs that are not permitted in food producing animals in the UK

A
  1. antibiotic growth promoters
  2. anabolic steroids (incl. oestrogens)
  3. beta-agonists (repro exception for clenbuterol)
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2
Q

this is the maximum concentration of an active ingredient (or its metabolites) permitted at the time of consumption;
determined from acceptable daily intakes (ADI) for that drug

(honey, meat, milk, eggs)

A

Maximum Residue Limit (MRL)

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3
Q

what are MRLs (maximum residue limit) used to set?

A

withdrawal periods

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4
Q

what is the withdrawal period for milk and eggs?

A

7 days

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5
Q

what is the withdrawal period for meat

A

28 days

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6
Q

what is the withdrawal period for fish?

A

500 day-degrees

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7
Q

these are chemicals used in the formulation of a medicine;
may be there to suppress bacterial growth, help solubility, extend shelf life ,etc;
must also be permitted for food producing animals

A

excipients

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8
Q

the Alpha2 receptor in this species is more sensitive to xylazine compared to other species

A

cattle

(individual response is HIGHLY variable)

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9
Q

where is the preferred site for IM injections

A

neck

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9
Q

where should adverse events involving drugs be reported?

A

VMD

`

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10
Q

name the type of antibiotic

mechanism: protein synthesis
gram neg: X
gram pos: ++
anaerobes: +

A

macrolides

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11
Q

name the type of antibiotic

mechanism: protein synthesis
gram neg: X
gram pos: ++
anaerobes: ++

A

lincosamides

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12
Q

name the type of antibiotic

mechanism: protein synthesis
gram neg: +
gram pos: +
anaerobes: +

A

tetracyclines

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13
Q

name the type of antibiotic

mechanism: protein synthesis
gram neg: ++
gram pos: +
anaerobes: X

A

aminoglycosides

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14
Q

name the type of antibiotic

mechanism: cell wall synthesis
gram neg: ++
gram pos: ++
anaerobes: +

A

cephalosporins

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15
Q

name the type of antibiotic

mechanism: cell wall synthesis
gram neg: X
gram pos: ++
anaerobes: ++

A

penicillin

16
Q

name the type of antibiotic

mechanism: cell wall synthesis
gram neg: +
gram pos: ++
anaerobes: +

A

aminopenicillins

17
Q

name the type of antibiotic

mechanism: folate metabolism
gram neg: +
gram pos: +
anaerobes: +

A

TMPS

18
Q

name the type of antibiotic

mechanism: DNA gyrase
gram neg: ++
gram pos: +
anaerobes: X

A

fluoroquinolones

19
Q

name 3 concentration-dependent (type 1) antibiotics

A
  1. most fluoroquinolones
  2. aminoglycosides
  3. metronidazole
20
Q

name 2 time-dependent (type 2) antibiotics

A
  1. penicillins
  2. cephalosporins
21
Q

name 3 mixed-effect (type 3) antibiotics

A
  1. some fluoroquinolones
  2. tetracyclines
  3. lincosamides
22
Q

name 4 antibiotics with poor tissue penetration

A
  1. penicillins
  2. cephalosporins
  3. beta-lactamase inhibitors
  4. aminoglycosides
23
Q

name 4 antibiotics with good tissue penetration

A
  1. TMPS
  2. lincosamides
  3. macrolides
  4. tetracycline
24
Q

name an antibiotic with very good tissue penetration

A

fluoroquinolones

25
Q

this is used to adjust usage by animal biomass;
multiply the number of animals by the standarised weight

A

population correction unit (PCU)

26
Q

this is the assumed average dose per kg animal per species per day;
based on the mean daily dose of all indications of that active ingredient

A

DDDvet

27
Q

this is the assumed average dose per kg animal per species per treatment course;
based on the mean course dose of all indications of that active ingredient

A

DCDvet

28
Q

what are the units for DDDvet and DCDvet for oral and injectable products

A

mg/kg animal

29
Q

what are the units for DDDvet and DCDvet for intramammary products lactating cow

A

units (UD)/teat (dairy cow)

30
Q

what are the units for DDDvet and DCDvet for intramammary products dry cow

A

units (UD)/udder (dairy cow)

31
Q

what are the units for DDDvet and DCDvet for intrauterine products

A

units (IUP)/animal