Drugs Used in Myocardial Infarction

Question 1

Treatment for MI

Answer 1

MONAAT

Morphine
O2
Nitrates
Anticoagulants
Antiplatelets
Thrombolytics (Fibrinolytics)

Question 2

Fibrinolytics

tissue plasminogen activator analog

Answer 2

1st GEN
Streptokinase
Urokinase

2nd GEN
Reteplase
Alteplase
Tenecteplase

Question 3

Antiplatelets

(-) aggregation

Answer 3

Aspirin
Clopidogrel
Abciximab
Dipyridamole

Question 4

COX (-)

Answer 4

ASPIRIN

Question 5

ADP (-)

Answer 5

Clopidogrel
Ticlopidine
Prasugrel
Ticagrelor

Question 6

GBIIb/IIIa (-)

Answer 6

Abciximab
Eptifibatide
Tirofiban

Question 7

PDE (-)

Answer 7

Dipyridamole

Cilostazol

Question 8

Indirect Thrombin Inhibitors

Answer 8

HEPARIN

Question 9

MOA of Regular/Unfractionated Heparin

Answer 9

(+) anti-thrombin – (-) IIa and Xa

Question 10

MOA of Low Molecular Weight Heparin

Answer 10

(-) Xa and 2a

Question 11

Binds and potentiates effect of antithrombin III on factor Xa

Answer 11

Enoxaparin
Dalteparin
Fondaparinux
Nadroparin

Question 12

Oral direct Xa Inhibitor

Answer 12

Apixaban

Rivaroxaban

Question 13

Direct IIa (Thrombin) Inhibitor

Answer 13

Dabigatran
Desidurin
Argatroban
Bivalirudin
Lepirudin

Question 14

Aspirin Dose s

Answer 14

LOW - <160 mg - ANTIPLATELET

INTERMEDIATE - 160-1200 mg - ANTIPYRETIC, ANALGESIC

HIGH - >1200 mg - ANTI-INFLAMMATORY

Question 15

Triad of Aspirin Hypersensitivity

Answer 15

SAMTER TRIAD

Asthma
Aspirin
Nasal polyps

Question 16

Aspirin Intoxication

Answer 16

Increased respiratory drive leads to hyperventilation and respiratory alkalosis

Question 17

Expected acid-base abnormality in salicylate poisoning

Answer 17

Respiratory alkalosis w/ HAGMA

Question 18

Antidote for Heparin toxicity

Answer 18

PROTAMINE

chemical antagonist of heparin

Question 19

Antidote for Warfarin

Answer 19

Vitamin K (fast)

FFP (slow)