Antihelminthic Drugs

Question 1

DOC for NEMATODES (ROUNDworms)

Answer 1

Albendazole and Mebendazole EXCEPT

Strongyloides, Onchocerciasis - Ivermectin

Pinworm - Pyrantel pamoate

Filariasis - Diethylcarbamazine (DEC)

Question 2

DOC for TREMATODES (Flukes)

Answer 2

Praziquantel EXCEPT

Fasciola hepatica - Bithionol

Question 3

DOC for TAPEWORMS (Cestodes)

Answer 3

Praziquantel EXCEPT

Cysticercosis and Hydatid Disease - Albendazole

Question 4

Increases membrane permeability to calcium – paralysis

Causes muscle paralysis, vacuolization and death

DOC for trematodes and cestodes

Trematodes
*Schistosoma, Paragonimus, Clonorchis, Opisthorchis, Fasciolopsis, Heterophyes)

Cestodes
*Taenia, Diphyllobothrium, Hymenolepsis

Answer 4

Praziquantel

Question 5

Uncouples oxidative phosphorylation or by activating ATPases

Answer 5

Niclosamide

Question 6

Microtubule inhibitors

DOC of hydatid disease

Answer 6

Albendazole

Question 7

DOC for whipworm infections

Answer 7

Mebendazole

Question 8

DOC for trichinosis

Answer 8

Thiabendazole

SE:
SJS

Question 9

DOC for filariasis and eye worm disease

Answer 9

Diethylcarbamazine (DEC)

Question 10

DOC for strongyloidiasis

Answer 10

Ivermectin

SE:
MAZZOTI REACTION - fever, headache, dizziness, rashes, pruritus, tachycardia, hypotension, pain in joints, muscles and lymph glands)

CORNEAL OPACITIES