Drugs on GI

Question 1

Bulk forming laxative

Answer 1

Psyllium (Metamucil)

Question 2

Bulk forming does what

Answer 2

attracting water and thus increasing fecal bulk

Question 3

Psyllium (Metamucil)

Answer 3

abdominal cramping, fainting

Question 4

Stool softeners/surfactants

Soften stool

Answer 4

Ducosate (Colase)

Question 5

Stool softeners/surfactants

do what

Answer 5

cause more water and fat to be absorbed into stools

Question 6

Ducosate (Colase)

Indication

Answer 6

Often used for prevention not treatment for constipation (surgery, injury and MI)

Question 7

Ducosate (Colase)

Adverse effects

Answer 7

abdominal cramping and diarrhea

Question 8

Histamine 2 antagonists

Answer 8

Ranitidine (Zantac)

Cimetidine (Tagamet), Famotidine (Pepcid)

Question 9

Ranitidine (Zantac)

Cimetidine (Tagamet), Famotidine (Pepcid) are used for

Answer 9

Widely prescribed for treating peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD)

Question 10

Dine’s nursing concerns

Answer 10

-Rapid absorption from small intestine (30 min onset of action)
-Short half-life/rapid excretion (from 1 to 4 hr)
No known effects on the fetus
-Differentiate from H1 antagonists (Benadryl against allergic rhinitis)
-Safety profile on higher dose, renal disease or older patients
-No antacids with H2 antagonists (Diminished absorption)

Question 11

Dine’s adverse effects

Answer 11

CNS: confusion, restlessness, hallucinations, depression
CV: arrhythmia
GI: elevated liver enzymes, N/V/D