Drugs Neuro Flashcards
1
Q
Gabapentin
A
antiepileptic
2
Q
Pregablin
A
antiepileptic
3
Q
Tiagabine
A
antiepileptic
Inhibits GABA reuptake
4
Q
Volparate
A
Antiepileptic
5
Q
Propanalol
A
Betaadrenoceptor
6
Q
Citalopram
A
SSRI
7
Q
Venlafaxine
A
SSRI
8
Q
Zolpidem
A
Benzo
9
Q
Triazolam
A
Benoz
10
Q
Loprazolam
A
Benoz
11
Q
Nitrazepam
A
Benzo
12
Q
Diazepam
A
Benzo
13
Q
Phenobarbitone
A
Barbituates (GABAa receptor enhancement) used as anxiolytic and anticonvulsant
14
Q
Busipirone
A
5-HT1a agonist - anxiolytic
15
Q
Ipsapirone
A
5-HT1a agonist - anxiolytic
16
Q
Gepirone
A
5-HT1a agonist - anxiolytic
17
Q
Olanzapine
A
Antipsychotics
18
Q
Risperidone
A
Antipychotic
19
Q
Zopiclone
A
Hypnotic
20
Q
Zolpidem
A
Hypnotic
21
Q
Chloral hydrate
A
Hypnotic
22
Q
Diphenhydramine
A
antihistamine
23
Q
Promethazine
A
Antihistamine
24
Q
Mepivacaine
A
LA
25
Bupivacaine
LA -> epidural
26
Prilocaine
LA intravenous e.g limb surgery
27
Tetracaine
Surface anesthesia LA cornea
28
Articaine
LA
29
Lignocaine
Surface anesthesia or intravenous or epidural e.g. limbs surgery
30
Thipentaie
Injection/intravenous Anesthetic
31
Propofol
Injection/intravenous Anesthetic
32
Etomidate
Injection/intravenous Anesthetic
33
Midazolam
Benzo (used as GA)
| Injection/intravenous Anesthetic
34
Ketamine
NMDA channel blocker
| Injection/intravenous Anesthetic
35
Nitrous Oxide
Inhalation anesthetics
36
Isoflurane
Inhalation anesthetics
37
Desflurane
Inhalation anesthetics
38
Sevoflurane
Inhalation anesthetics
39
Atropine
Muscarinic antagonists
40
Atracurium
NMJ blovking agent (GA use)
41
Tiletamine
Dissociative anaesthetic
42
Morphine
opioid
43
Heroin
opioid
44
Codeine
opioid
45
Oxycodone
Opioid
46
Methadone
Opioid
47
Pethidine
opioid will cross placenta
48
Pentazocaine
Opioid
49
Fentanyl
Opioid
50
Remifentanyl
Opioid
51
Buprenorphine
Opioid
52
Tramadol
opioid/ Noradrenaline re-uptake inhibitor
53
Nalozone
Opioid receptor antagonist to prevent abuse
54
Naltrexone
Opioid receptor antagonist to prevent abuse
55
Dextromethorphan
Cough suppressant (non-opioid)
56
Co-codamol
codeine and paracetamol
57
Co-codraprin
Codeine and aspirin
58
Co-proxamol
dextropropoxyphene + paracetamol
59
Carbamazepine use
Trigeminal neuralgia
| Na channel blocker (anticonvulsant)
60
Gabapentin/pregablin use
Diabetic neuropathy
61
Amtitriptyline
Antidepressant used in post herpatic neuralgia
62
Sodium valporate
Anticonvulsant
1. potentiate GABA actions at GABAa R
2. Inhibits GABA transaminase
3. Inhibitis SSA dehydrogenase
4. blocks voltage-gated sodium channels
63
Felbamate
1. Potentiate GABA actions at GABAa R (anticonvulsant)
| 2. NMDA antagonist anticonvulsant
64
Perampenal
AMPA antagonists (anticonvulsant)
65
Carbamaxepine
blocks voltage-gated sodium channels
| Anticonvulsant action
66
Oxcarbazepine
blocks voltage-gated sodium channels
| Anticonvulsant action
67
Phenytoin
1. blocks voltage-gated sodium channels
2. Block of voltage-activated calcium channels
Anticonvulsant action
68
Lamotrigine
1. blocks voltage-gated sodium channels
2. Block of voltage-activated calcium channels
Anticonvulsant action
69
Ethosuximde
Block of voltage-activated calcium channels (low voltage)
70
Gabapentin
Specifically blocks transport of voltage-gated calcium channels to the membrane
71
Topiramate
```
Treatment of migraine along with anticonvulsant
Multpiple actions (GABA, block sodium and calcium, Blocks AMPA)
```
72
Levetiracetum
anticonvulsant
73
Zonisamide
Na channel block - anticonvulsant
74
Retigabine
Activates KCNQ potassium channels
75
Busipirone
Post-synaptic receptor agonist of monoamines
76
Mirazepine
Pre-synaptic receptor antgonists for monoamine
| Anti-D
77
Moclobemide
MAOIs
| Anti-D
78
Phenylzine
MAOIs
| Anti-D
79
Fluoextine
SSRI
| Anti-D
80
Iproniazid
MAOI
| Anti-D
81
Imipramine
TCA
| Anti-D
82
Amitriptyline
TCA
| Anti-D
83
Clomipramine
TCA
| Anti-D
84
Despiramine
TCA
| Anti-D
85
Paroxetine
SSRI
| Anti-D
86
Reboxetine
Selective Noradrenaline reuptake inhibitor
| Anti-D
87
Trazadone
5-HT2 antagonists + SSRI
| Anti-D (atypical)
88
Nefazedone
5-HT2 antagonist +SNRI/SSRI
| Anti-D (atypical)
89
Mianserin
Alpha-adrenoceptor and 5-HT and 5-HT antagonist
| Anti-D (atypical)
90
Mirtazepine
Alpha-adrenoceptor and 5-HT and 5-HT antagonist
| Anti-D (atypical)
91
Lithium
mood stabiliser
92
Fuoxetine
SSRI
93
Agonelatine
Melatonin agonists and 5-HT2 antagonist
94
Phenothiazines
Primary D2-receptor antagonists
| Typical anti-pyschotics
95
Chlorpromazine
Primary D2-receptor antagonists
| Typical anti-pyschotics
96
Fluphenazine
Primary D2-receptor antagonists
| Typical anti-pyschotics
97
Thioridazines
Primary D2-receptor antagonists
| Typical anti-pyschotics
98
Butyrophenones
Primary D2-receptor antagonists
| Typical anti-pyschotics
99
Haloperidol
Primary D2-receptor antagonists
| Typical anti-pyschotics
100
Pimozide
Primary D2-receptor antagonists
| Typical anti-pyschotics
101
Clozapine
Also know as Serotonin (5-HT2) and dopamine (D2) antagonists
| Atypical antipyschotics
102
Risperidone
Also know as Serotonin (5-HT2) and dopamine (D2) antagonists
| Atypical antipyschotics
103
Quetoapine
Also know as Serotonin (5-HT2) and dopamine (D2) antagonists
| Atypical antipyschotics
104
Zotepine
Also know as Serotonin (5-HT2) and dopamine (D2) antagonists
| Atypical antipyschotics
105
Aripriprazole
Also know as Serotonin (5-HT2) and dopamine (D2) antagonists
| Atypical antipyschotics
106
Sertaline
SSRI
107
Rupropion
MOAI (DA) smoking cessation
108
Methylphenodate
Ritalin
| ADHD
109
Atomoxetine
MOAI (NA)
110
Modafinil
Cognitiveenhancers
111
Fenfluramine
SSRI
112
Sibutramine
NA/5-HT re-uptake inhibitorq
113
Romonabant
Selective CB1 receptor blocker
114
Lorcaserin →
Selective 5-HT2c receptor agonist
115
Orlistata
Lipase inhibitor which prevents fat breakdown and absorption.
116
a. Levodopa (L-Dopa)
dopamine agonist
117
Prampipexole (Mirapexin)
Direct Dopamine Receptor Agonists:
118
Ropinirole (eg Adartel, Requip)
Direct Dopamine Receptor Agonists:
119
Rotigotine (Neupro)
Direct Dopamine Receptor Agonists:
120
Selegiline
Inhibitors of dopamine metabolism:
| Irreversible MAO-B inhibitor
121
Rasagiline
Inhibitors of dopamine metabolism:
122
Entacapone
Inhibitors of dopamine metabolism:
123
Tolcapone
Inhibitors of dopamine metabolism:
124
Amantidine:
Antiviral agent
| Parkinsons
125
Memantine:
NMDA receptor antagonist
