Drugs deck Flashcards
lidocaine
local anaesthetic
prilocaine
local anaesthetic
bupivicaine
local anaesthetic
amoxycillin
antibiotic
clindamycin
dental go-to antibiotic
acyclovir
antiviral drug used topically or systemically
nystatin
topical anti fungal
fluconazole
systemic orally administered anti fugal
NSAID’s
non-steroidal anti-inflammatory drugs which reduce the inflammatory mediators
corticosteroids
anti-inflammatory drugs which reduce the inflammatory process
paracetamol
anti-pyretic analgesic
diclofenac
NSAID used to prevent the formation of COX1 and COX2 in the cyclo-oxygenase pathway to prevent the formation of prostaglandins
arachidonic acid
inhibits cyclo-ocygenase pathway if not formed, to prevent the formation of prostaglandin
aspirin
NSAID used to inhibit COX1 pathway and thus reduce inflammatory mediators
- anti platelet by causing an irreversible change to the platelet to prevent aggregation
ibuprofen
NSAID with similar but less potent action than aspirin (COX1 pathway)
dexamethasone
systemic corticosteroid to reduce inflammatory pathway after surgery
hydrocortisone cream
corticosteroid cream (topical) to reduce inflammatory pathway in eczema patients
benzodiazepine midazolam
anxiolytic
nitrous oxide
anxiolytic gas
GTN
spray absorbed trans-mucosally to treat angina attacks
glucagon
treats diabetic hypo’s
diprymadole
antiplatelet
- inhibits the platelet phosphodiesterase to prevent coagulation
warfarin
anti-coagulant
- inhibits the clotting factors that require vitamin K for synthesis
- monitored using the INR
apixaban
anticoagulant
clopidrogel
anti platelet that inhibits ADP induced platelet aggregation
statins
- coA reductase inhibitors
- inhibit cholesterol synthesis in the liver (helps atherosclerosis)
atenolol
beta 1 blocker
- blocks the effect of adrenaline on the heart
- makes the heart rate slower
propanolol
beta 1 and beta 2 blocker
- good for anxious patients
thiazide
diuretic to reduce fluid volume by increasing salt and decreasing water
loop diuretic
works on the loop of henle
nitrates
(GTN)
- dilate veins and resistance arteries to reduce preload and the cardiac workload
calcium channel blockers
treats hypertension as it blocks calcium channels in smooth muscles (cardiac muscle too) to reduce tension
ace inhibitors
- end in pril
- inhibits the conversion of angiotensin 1 to angiotensin 2
- therefore reducing the effect of the vasoconstrictor and the BP
elanapril
ace inhibitor to reduce BP
bronchodilators
ensure airways stay open to increase ventilation in the alveoli
- beta 2 agonist (dilator)
- anticholinergic (prevents muscle constriction)
chromoglycate
prevents mast cell degranulation in asthma
- leukotriene receptors antagonists which leads to airway narrowing
opioids and benzodiazepines
slow down breathing
theophylline
respiratory stimulant
- helps in gas exchange problems to stimulate respiratory drive
meter dose inhaler
- produces high velocity suspensions of the bronchodilator
ipratropium (grey inhaler)
inhibits the muscarininc nerve transmission in autonomic nerves to dilate the bronchi and decrease mucus secretion
anticholinergic
leukotriene inhibitors
prevent inflammatory triggers from firing but inhibits leukotriene
fluticasone
inhaled steroid
beta-adrenergic agonists
- relax bronchial smooth muscle to reduce bronchoconstriction and resting bronchial tone to act as a protective measure against asthma
pancreatic enzymes
given to patients with CF to help digest fats
Dnase
breaks down mucus
- helpful in CF patients
ACE inhibitors
prevent the conversion of angiotensin 1 to 2
- therefore lowers BP and prevents reabsorption of salt and water in the kidneys
- prevents vasoconstriction
- enalapril, (anything ending in “-pril”)
acyclovir
antiviral
- helps to treat herpes infections
adrenaline
beta blocker
- activates the sympathetic nervous system
- fight or flight
- increases vasoconstriction, bronchial constriction, heart rate
amoxycillin
antibiotic
- penicillin based
- treating UTI’s and other minor bacterial infections
analgesic
anything to relieve pain
- NSAIDs, paracetamol, aspirin, cocodamol, morphine
antacids
- eliminate stomach acid
- alkaline based
anti-cholinergic
bronchodilators
- beta agonist
- inhibit nerve transmission in smooth muscles
anti-diuretic hormone
- ADH
- decreases urine production
- increases salt and water retention in the body
- given to patients with diabetes mellitus as they can no longer concentrate urine
anticonvulsant
treats epileptic seizures
anxiolytic
opioids and benzodiazepines to help relax and reduce anxiety
articaine
local anaesthetic
- stronger than lignocaine
- contains adrenaline
aspirin
- NSAID
- anti platelet
- thins blood
- permanently affects platelets until they are recycled (7-10 days)
- given to patients with hypertension and MI risk
atenolol
beta blocker
- slows down HR
- reduces heart force
- patients with MI risk
atropine
cholinergic blocker
- targets the parasympathetic system
- prevents constriction of smooth muscle cells
beta blockers
- prevent the action of adrenaline on the heart
- impair ventilation however, careful with patients with COPD and asthma
beta-2 agonist
- bronchodilators
- prevents smooth muscle constriction
- short acting to treat acute bronchial constriction
- long acting as a prophylactic measure
benzodiazeipine
- anticonvulsant
- anxiolytic
- relaxant
biguanides
- insulin sensitiser
- given to type 2 diabetics
calcium channel blockers
inactivate calcium channels in smooth muscles
- prevent constriction of blood vessel walls
- can cause gingival hyperplasia
carbimazole
treats hyperthyroidism
- can cause hypothyroidism if used too much
corticosteroid
artificial cortisol
- reduce inflammatory processes
- steroid
- anti-inflammatory drug
COX inhibitors
- inhibit the pathway of COX to COX 2
- NSAIDs
- ibuprofen and aspirin
- interact with other medications
- can cause GI bleeding, kidney and liver problems
- prevents synthesis of prostaglandin from arachidonic acid
- anti-inflammatory and analgesic
dabigatran
- anticoagulant
digoxin
- cardiac stimulator
- used to treat patients with heart failure
diuretics
- decrease salt and water reabsorption in the kidneys
- e.g. thiaside
- dilutes the urine
- treats HBP by reducing fluid volume
fluconazole
oral antifungal
- reacts with warfarin
- treats candida infections
glucagon
- increases blood sugars
GTN
- short acting nitrate therapy
- treats angina
- 3 sprays under the tongue
- glyceryl trinitrate
H2 receptor blockers
- reduce acid secretion in the stomach
- prevent histamine activation of acid production
- not as good as PPI as the acetylcholine and gastrin activation still occurs
ibuprofen
- NSAID
- COX inhibitor
- propionic acid derivative
insulin
decreases blood glucose levels
- used for type 1 diabetics
insulin sensitisers
used in type 2 diabetics
- increase cell response to glucose
- biguanides and thiazolidinediones
interferon
anti viral
- interferes with viral replication
insulin secretagogue
- increases insulin secretion
- type 2 diabetics
- sulphonylureas
ipratropium
- anticholinergic
- beta antagonist
lidocaine
- local anaesthetic
- contains adrenaline
metronidazole
- antibiotic
- common
- oral infection, h.pylori, triple therapy
nitrate therapy
- treats angina
- long and short acting
- dilates veins and resistance arteries
- decreases preload
nitrous oxide
- anxiolytic
- inhaled
NSAID
reduce prostaglandin production
- common drug interactions
- not to be given to patients with bleeding disorders, renal disease, liver failure
- COX inhibitor
omeprazole
- proton pump inhibitor
- reduces stomach acid production
opium
used in sedation and analgesia
oxygen
- chronic lung conditions such as COPD
- acute conditions such as CI
- classed as a drug if used in any concentration greater than found in the air
oxytocin
- produced by the posterior pituitary
- causes labour
paracetamol
- anti pyretic (prevents fever)
- analgesic
- 500mg tablets
- max dose 4g/day
- overdose = liver failure
prednisalone
- corticosteroid
- prevents transplant rejection
- 4x stronger than hydrocortisone
- therapeutic steroid
- treats IBD
prilocaine
- local anaesthetics
- doesn’t contain adrenaline
proton pump inhibitors
prevent/reduce acid secretion in the stomach
- block the proton pump in the parietal cell
salbutamol
- inhaled beta agonist
- used for short acting asthma inhaler
salmeterol
- long acting beta 2 agonist
simvastatin
- stainin
- used to treat atherosclerosis
- reduces blood cholesterol
somatostatin
- inhibits the effector insulin and glucagon
- inhibits GH
statin
liid lowering drugs
- reduce cholsterol
- atherosclerosis patients
sulphonylureas
- insulin secretagogue
- increase insulin secretion
- oral hypoglycaemic agent
theophylline
- bronchodilator
- respiratory stimulant
- improve ventilation when there is a gas exchange problem
thyroxine
- T4
- treats hypothyroidism
warfarin
- anticoagulant
- increases prothrombin time
NOAC
new oral anti coagulant
- apixaban
- dabigatran
- prevent clot formation
bupivicaine
local anaesthetic
nystatin
anti fungal
- topical
diclofenac
- phenyl acetic acid derivative
- effective analgesic
- NSAID
hydrocortisone
topical corticosteroid
dexamethasone
- prevents swelling
- corticosteroid
- often given after wisdom tooth removal
infliximab
anti TNFa
- stop inflammation
ursodeoxycholicacid
prevent the build up of bile acid
colestyramine
prevents bile acid reabsorption from the GIT
triple therapy
- used to treat PUD
- removes H.pylori
- 2 antibiotics (amoxycillin and metronidazole)
- 1 PPI (omeprazole)
oral contraceptives
increased hypertension and clotting
dual anti platelet therapy
aspirin and clopidrogel
- used for patients with mechanical heart valves
sympathomimetics
increase risk of hypertension
clopidrogel
anti platelet
-inhibits ADP induced platelet aggregation
- given with aspirin for a dual effect
dipyridamole
- inhibits platelet phosphodiesterase
- anti platelet
chromoglycate
prevents mast cell degranulation in asthmatic patients
leukotriene receptor antagonists
prevent mast cell degranulation in asthmatic patients
drugs used to increase ventilation
bronchodilatos and anti inflammatory
respiratory depressants
benzodiazepines
and opioids
BAD
breath activated device
MDI
meter dose inhaler
fluticasone
inhaled corticosteroid
beclomethasone
inhaled corticosteroid
betamethasone
inhaled corticosteroid
fludrocortisone
mimics aldosterone
AT2 blocker
angiotensin 2 blocker
- prevents angiotensin production by blocking the receptor
- inhibits aldosterone production
nephrotoxic drug
cyclosporin
- immunosuppressant
prasugrel
anti platelet
tricagrelor
anti platelet