DIGESTIVE SYSTEM Flashcards

1
Q

what is the function of the digestive system?

A

to break down the food we eat, release their nutrients, and absorb those nutrients in the body.

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2
Q

what is the workhorse of the digestive system?

A

the small intestine is where majority of digestion occurs.

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3
Q

the organs of the digestive system are divided into 2 main categories. what are they?

A
  • alimentary canal
  • accessory digestive organs
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4
Q

what is the alimentary canal and the organs it contains?

A

the alimentary canal is also called the gastrointestinal tract.
- the tube is about 25 feet long in length and starts at the mouth and ends at the anus.
- organs: mouth, pharynx, esophagus, stomach, small and large intestine, rectum, and anus.
MAIN FUNCTION: nourish the body.

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5
Q

what are the 4 tissue layers in the alimentary canal?

A

mucosa, submucosa, muscularis, and serosa

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5
Q

what is the “accessory digestive organs”?

A

each of the accessory digestive organs helps in the breakdown of food.
- within the mouth, the teeth and tongue begin mechanical digestion but the SALIVARY GLANDS begin chemical digestion.
- once food enters the small intestine, the GALLBLADDER, LIVER, PANCREAS release bile and enzymes for digestion to continue.

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6
Q

what is the mucosa?

A

first tissue layer.
- epithelium: in the mouth, pharynx, esophagus, and anal canal, the epithelium is stratified squamous epithelium. in the stomach and intestines it is simple columnar epithelium.
AMONG THE THE EPITHELIAL CELLS ARE GOBLET CELLS THAT SECRETE MUCUS INTO LUMEN AND ENTEROENDOCRINE CELLS THAT SECRETE HORMONES.
- lamina propria: connective tissue and has lymphatic and blood vessels
- muscularis mucosa: smooth muscle

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7
Q

what is the submucosa?

A

second tissue layer.
- includes blood and lymphatic vessels including the submucosal plexus/plexus of meissner: plays a role in regulation of secretion, blood flow, smooth muscle activity, etc.

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8
Q

what is the muscularis?

A

third tissue layer.
- double layer of smooth muscle: inner circular layer and outer longitudinal layer.
- responsible for the movement of the digestive tract through peristalsis
the mouth, pharynx, and proximal part of the esophagus, and anal sphincter, the muscularis is made up of skeletal muscle for voluntary control over swallowing and defecation.

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8
Q

what is the serosa?

A

fourth tissue layer.
- present only in the region of the alimentary canal within the abdominal cavity.
- instead of the serosa, the mouth, pharynx, and esophafus have adventitia.

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9
Q

what do the cranial nerves do for us when we eat?

A
  • able to feel the food so we dont bite ourselves
  • provide taste to the food
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10
Q

what is the function of blood vessels in terms of the digestive system?

A
  • transport protein and carbohydrate nutrients after the food is digested.
  • supply organs of the alimentary canal with nutrients and oxygen needed to drive their cellular processes.
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11
Q

what arteries supply the alimentary canal, liver, stomach, duodenum. small intestine, large intestine?

A
  • proximal parts of the alimentary canal supplied with arteries branching off of the aortic arch and thoracic aorta.
  • inferior part of the alimentary canal: arteries branching off of the abdominal aorta.
  • liver, stomach, duodenum: celiac trunk
  • small and large intestine: superior and inferior mesenteric arteries
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12
Q

the veins that collect the nutrient rich blood from the small intestine empty into the?

A

hepatic portal system which takes the blood to the liver where the nutrients are either processed or stored for later use. then the blood goes back to the heart.

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13
Q

the digestive organs within the abdominal cavity are held in place by the?

A

peritoneum. made up of parietal peritoneum which lines the abdominal wall, visceral peritoneum which surrounds the organs, and in between is the peritoneal cavity including the fluid.

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14
Q

the processes of digestion include 6 activities:

A

ingestion, propulsion, mechanical digestion, chemical digestion, absorption, and defecation

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15
Q

what is ingestion?

A

ingestion refers to the entry of food into the alimentary canal through the mouth.
- the food is chewed and mixed with saliva that contain enzymes that break down carbohydrates and some lipids.

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16
Q

what is propulsion?

A

movement of food through the digestive tract.
- peristalsis is the contraction and relaxation of the longitudinal and circular muscle layers of the wall in the alimentary canal which propel food along.

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17
Q

what is mechanical digestion?

A

purely physical process that does not change the chemical nature of the food.
- involves chewing/mastication and tongue movements to make food into smaller pieces.
- occurs in the mouth, the stomach does mechanical churning of food and when mixed with gastric juices becomes chyme, and also in the small intestine via segmentation

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18
Q

what is chemical digestion?

A

chemical digestion is the breakdown of complex food molecules into their building blocks. ex: protein into amino acids.
- chemical digestion begins in the mouth, then stomach, and then small intestine which is the primary site and it is completed here.

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19
Q

what is absorption?

A

absorption is the process by which nutrients from digested food enter the bloodstream or lymphatic system.
- small intestine is the primary site of absorption.
- large intestine: absorption here primarily involves reabsorption of water and electrolytes, and maybe some vitamins.

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20
Q

what is defecation?

A

the final step in digestion, undigested materials are removed from the body as feces.

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21
Q

what is the oral cavity?

A

cheeks, tongue, and palate.
the lips/labia regulate what comes in and out of the mouth and responsible for facial expressions.

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22
Q

the main open area of the mouth/oral cavity runs from the?

A

gums/teeth to the fauces.

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23
Q

talk about the palates: hard and soft?

A

roof of the mouth:
the hard palate is bony: palatine and maxilla.
the soft palate is muscular: allows for swallowing, singing, yawning.

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24
Q

what is the uvula?

A

small tissue hanging down from the soft palate that helps prevent food from entering the nasal cavity during swallowing.

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25
Q

what is the tongue attached to?

A

mandible and styloid processes of temporal bones and the hyoid bone.
- intrinsic and extrinsic muscles that are responsible for optimal chewing, gather food into bolus, position food so it can be swallowed.
papillae: extensions of lamina propria of mucosa that contain taste buds and touch receptors.

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26
Q

what are the major salivary glands and what does saliva contain?

A

saliva composition: 95% water, ions, enzymes, glycoprotein
major types: submandibular, sublingual, parotid glands

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27
Q

what is the function of saliva?

A

lubricate food, facilitate movement, swallowing, bolus formation

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28
Q

what glands secrete salivary amylase and what does it do?

A

the parotid glands are major salivary glands that secrete salivary amylase which is an enzyme that begins the chemical digestion of starch. it breaks down starch into simpler sugars.

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29
Q

which glands contain mostly mucous cells?

A

sublingual glands: they secrete the thickest saliva with the least amount of salivary amylase.

30
Q

a little bit about teeth?

A

32 permanent teeth
incisors: sharp front teeth for biting
canines: pointed teeth for tearing food
premolars and molars: flat with cusps for mashing/grinding

31
Q

what is the pharynx?

A

the pharynx aka throat is involved in both digestion and respiration.
divided into nasopharynx, oropharynx, and laryngopharynx

32
Q

what is the esophagus?

A

muscular tube that connects the pharynx to the stomach. it is 10 inches in length. located posterior to the trachea. to enter the abdomen, it penetrates through the diaphragm.

33
Q

what are the sphincters in the esophagus?

A

upper esophageal sphincter: controls the movement of food from the pharynx into the esophagus.
lower esophageal sphincter: also known as cardiac sphincter controls passage of food from the esophagus into the stomach.

34
Q

what is the upper two thirds of the esophagus made of?

A

smooth and skeletal muscle

35
Q

what does the mucosal secretions of the esophagus do?

A

lubricate the food and lining of the esophagus

36
Q

what are the functions of the stomach?

A
  • stores and holds food before it moves into the small intestine.
  • mechanical digestion: stomach mixes food with digestive juices to form chyme.
  • chemical digestion: continues the digestion of carbohydrates and begins digestion of proteins and lipids.
36
Q

what is deglutition?

A

another word for swallowing:
has 3 phases:
voluntary phase: begins when food is mixed with saliva to form a.
pharyngeal phase: involuntary and when the bolus reaches the pharynx
esophageal phase: when bolus enters the esophagus and continues until it reaches the stomach.

36
Q

what is the size and capacity of the stomach?

A

highly expandable: capable of holding up to 4 litres of food and fluid.
- rugae are large folds in the stomach that allow it to stretch and expand.

36
Q

what are the regions of the stomach?

A

cardia, fundus, body, and pyloris

37
Q

what do parietal cells secrete?

A

secrete hydrochloric acid

38
Q

what do chief cells secrete?

A

pepsinogen which converts to pepsin using hcl.

39
Q

what do mucous neck cells secrete?

A

thin acidic mucus

40
Q

what do enteroendocrine cells secrete?

A

hormones like gastrin which stimulate secretion of hcl

41
Q

what are the 3 phases of gastric secretion?

A

cephalic, gastric, and intestinal phase

42
Q

what is the cephalic phase?

A

first phase of gastric secretion.
- it takes place before the food enters the stomach.
- begins before food even enters the stomach
- depression can suppress this reflex

43
Q

what is the gastric phase?

A

second phase of gastric secretion
- takes place when food enters the stomach

44
Q

what is the intestinal phase?

A

third phase of gastric secretion:
- takes place when the chyme enters the small intestine.

45
Q

what is the small intestine?

A

chyme from the stomach enters the small intestine which is the primary digestive organ in the body and also where most absorption occurs.
- 10 feet
- divided into duodenum, jejunum, and the ileum

46
Q

what is the duodenum?

A

the shortest part of the small intestine is the duodenum.
- it begins at the pyloric sphincter
- hepatopancreatic ampulla is located in the duodenal wall and it is where the bile duct and the pancreatic duct converge.
there is also the hepatopancreatic sphincter that regulates flow of bile and pancreatic juice from the ampulla into the duodenum.

47
Q

what is the jejunum?

A

it is the second part of the small intestine connecting the duodenum to the ileum.

48
Q

what is the ileum?

A

the ileum is the third part of the small intestine and is also the longest one. the ileum joints the cecum which is the first portion of the large intestine at the ILEOCECAL SPHINCTER.

49
Q

what is the jejunum and ileum tethered to the abdominal wall by?

A

mesentery.

50
Q

what special feature does the small intestine have?

A

villi and microvilli that increase surface area for better absorption. they are more abundant in the proximal 2/3rds of the small intestine where majority of absorption occurs.

51
Q

what is the function of circular folds in duodenum?

A

the shape causes the chyme to spiral which slows down digestion in order for nutrients to be absorbed fully.

52
Q

what is the function of the intestinal glands?

A

glands that secrete intestinal juice that is alkaline: neutralizes the acidic chyme and lubricates.

53
Q

what happens when most of the chyme has been absorbed?

A

the small intestine wall becomes less distended and the mucosa secretes motilin which is a hormone that initiates peristalsis..

54
Q

what is the large intestine?

A

the terminal part of the alimentary canal
the main function is to finish absorption of nutrients and water, synthesize vitamins, form and eliminate feces.
- runs from the appendix to the anus.
- divided into the cecum, colon, rectum, and anus.

55
Q

what is the cecum?

A

the first part of the large intestine. it receives the contents of the ileum. the appendix attaches to the cecum.

56
Q

what is the colon?

A

the cecum leads to the colon. there is the ascending colon, transverse colon, and the descending colon. it then leads to the sigmoid colon.

57
Q

what is the rectum?

A

the food residue leaving the sigmoid colon enters the rectum. there are also rectal valves here that separate the feces from gas to prevent simultaneous passage of feces and gas.

58
Q

what is the anal canal?

A

the food residue reaches the last part of the large intestine which is the anal canal. the anal canal contains the internal and external anal sphincter.
internal anal sphincter: smooth muscle and involuntary
external anal sphincter: skeletal muscle which is voluntary
usually both are closed unless during defecation

59
Q

what are the main functions of the large intestine?

A
  • water and electrolyte absorption
  • formation and storage of feces
  • vitamin production
  • elimination of waste
60
Q

what accessory digestive organs play a large role in chemical digestion in the small intestine?

A

liver, pancreas, and gallbladder.

61
Q

what is the liver and what does it do?

A

the liver is the largest gland in the body.
it has two main lobes: larger right lobe and smaller left lobe.
- the hepatic artery delivers oxygenated blood to the liver
- the hepatic portal vein brings nutrient rich deoxygenated blood from the intestines to the liver.
- important for bile: talk about this later

62
Q

talk about bile?

A

BILE: bile is a mixture secreted by the hepatocytes in the liver to accomplish the emulsification of lipids in the small intestine. MIXING LIQUIDS THAT DONT USUALLY MIX.
bile also removes waste such as BILLIRUBIN and facilitates the absorption of fat soluble vitamins.
- when the chyme enters the small intestine it stimulates the release of secretin which produces more bile and the gallbladder releases it in the small intestine.
- the gallbladder stores and concentrates bile between meals.
- bile salts are reabsorbed in the ileum and returned to the liver through hepatic portal vein.

63
Q

what is bilirubin?

A

main bile pigment: it is produced during the breakdown of rbc.
- elevated levels of bilirubin cause jaundice

64
Q

talk about pancreas exocrine function…

A

the pancreas secretes pancreatic juice which is rich in digestive enzymes.

65
Q

talk about pancreas endocrine function…

A

islets of langerhans: produce insulin, glucagon, somatostatin, pancreatic polypeptide.

66
Q

whats the gallbladders function?

A

small muscular sac that stores and concentrates bile and releases it into the small intestine when needed for digestion

67
Q

how are large food molecules broken down into subunits small enough to be absorbed ?

A

via hydrolysis.

68
Q

what are named of the salivary enzymes?

A

salivary amylase: begins digestion of carbs, secreted by the salivary glands.
lingual lipase: begins digestion of fats, secreted by lingual glands in the tongue.

69
Q

what are the gastric enzymes?

A

pepsin: breaks down protein into amino acids, secreted as pepsinogen by the chief cells which is activated by hcl
gastric lipase: breaks down triglycerides and produced by chief cells

70
Q

what are brush border enzymes?

A

enzymes located on the microvilli in small intestine.
lactase:breaks down lactose into glucose and galactose
maltase: breaks down maltose into 2 glucose
sucrase: breaks down sucrose into glucose and fructose.
nucleotidase/phosphatases: breaks down nucleotides and removes phosphate group
peptidase: remove amino acids off of peptide chains

71
Q

what are pancreatic enzymes?

A

pancreatic amylase: breaks down carbs
pancreatic lipase: breaks down triglycerides
nucleases: breaks down dna and rna
trypsin: protein into smaller peptides.
chymotrypsin: breaks down protein into smaller peptides.
carboxypeptidase: removes amino acids from peptide chains.
acinar cells produce this.