Dialysis Flashcards
what is diffusion?
the process by which particles move from an area of high concentration to an area of low concentration, across a semi-permeable membrane
name two factors that affect diffusion
concentration gradient
molecular weight of solute
name four toxins that can be removed by dialysis
urea
creatinine
potassium
sodium
what can be infused during dialysis and how?
bicarbonate
concentration is higher in the dialysate than the blood so it diffuses
what flow rate is required for haemodialysis to be effective?
300-350 ml/min
what are the four vascular access options for haemodialysis?
arteriovenous fistula
arteriovenous graft
tunnelled central venous catheter
temporary venous catheter
what is another name for a temporary venous catheter?
vasacath
what vascular access would be used in someone requiring acute short term dialysis?
temporary venous catheter
at what rate is dialysate usually ran at in haemodialysis?
500ml/min
= around 120L in a four hour treatment
what does dialysate consist of?
pure water
electrolytes (Na, K, HCO3)
glucose
how is excess fluid removed from a patients blood during dialysis?
a pressure gradient is set up between blood and dialysate
this forces water and all of the solutes in it to leave the blood
what is the movement of water out of the blood in dialysis called?
the convective solute drag
what is the whole process of water loss and the solute drag in dialysis called?
ultrafiltration
what is the usual range set for ultrafiltration in a dialysis session?
1-3L
what is affected by adsorption?
plasma proteins
any solutes bound to them
what happens to plasma proteins in adosrption?
become stuck to the membrane of the dialysis kidney
removed by membrane binding
how is most solute removed in haemodialysis?
diffusion
how is most solute removed in hemodiafiltration?
convection
massive amounts of ultrafiltration