Diabetes Flashcards
What is diabetes?
Syndrome with chronic high blood glucose
People with diabetes often have what else?
High BP
High cholesterol
What is the normal blood glucose level?
5 mmol/l
Where does insulin go to in the body when released from the pancreas?
Liver - 50%
Rest of the cells in the body
What is the range for HYPOglycaemia?
What is the range for HYPERglycaemia?
> 11mmol/l
What is a syndrome?
Collection of symptoms and signs that may be due to more than one cause
What are the signs and symptoms of diabetes?
Thirst
Polyuria
Weight loss
Tiredness
Dry mouth
Weight loss
Glycosuria
Hyperglycaemia
What ethnic group is diabetes most commonly in?
Asians
Afro-Caribbeans
What does the diagnosis of diabetes depend on?
High and randon blood glucose
Fast blood glucose > 7mmol/l
HbA1c = 48mmol/mol
What is the glucose tolerance test?
24h fast
75g of glucose given - 45 mins later blood glucose should be normal
What is the normal HbA1c?
30-35mmol/l
What is type 1 (insulin dependent) diabetes?
Autoimmune destruction of the beta islet cells
Usually young
What antibody tests should be undertaken for diagnosing type 1 diabetes?
Islet cell antibodies (ICA)
Islet antigen-2 (IA2)
GAD
Is there a family history with type 1 diabetes?
Often other endocrine disorders in patient/family