Development of the urogenital system Flashcards

1
Q

What does the intermediate mesoderm form?

A

It forms the urogenital ridge which will then give rise to the nephrogenic cord
and the gonadal ridge which gives rise to the male/female genital tract

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2
Q

What does the medially positioned gonadal ridge give rise to?

A

ovary/testis (male/female genital tract)

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3
Q

Where does the pronephros develop from?

A

The neck region

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4
Q

Where does the mesonephros develop from?

A

thorax/lumbar region

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5
Q

Where does the metanephros develop from?

A

The pelvic region

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6
Q

Where does the kidney develop from in the mammal?

A

The metanephric region

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7
Q

What are the two sources that the metanephros develops from?

A

The Ureteric bud or the metanephrogenic bud

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8
Q

Where does the ureteric bud grow out of?

A

Grows out of the mesenephric duct and eventually develops into the ureter, renal pelvis and collecting ducts

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9
Q

What does the metanephrogenic mass form?

A

Outer part of the mass forms the capsule and interstitium of the kidney, the inner parts form the nephrons

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10
Q

What does the urorectal septum divide the cloaca into?

A

Dorsal, Rectum, anal canal and anal membrane

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11
Q

What is the trigone?

A

triangular region located in the dorsal wall of the bladder neck formed by longitudinal smooth muscle from the ureters

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12
Q

Where do the gonads develop from?

A

gonadal ridge which is a thickening of the intermediate mesoderm

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13
Q

What are the two types of cells that the gonad contains?

A

Supporting cells and germ cells

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14
Q

What do the supporting cells form?

A

cellular cords

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15
Q

What do germ cells proliferate and migrate inside of

A

The gonadal cords so that they can be surrounded by supporting cells

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16
Q

What can an indifferent gonad then become?

A

either an ovary or testis

17
Q

What do the germ cells within the seminiferous cords become?

A

spermatogonia

18
Q

What happens to the seminiferous cords during puberty?

A

They canalise to become tubules, germ cells within begin to initiate spermatogenesis

19
Q

What happens to the cord cells that lack germ cells?

A

They become part of the rete testis

20
Q

What do the supporting cells differentiate into?

A

either leydig cells or sertoli cells

21
Q

What is the name of the cells that are in the walls of the seminiferous tubules and suppress both spermatogenesis and female duct development ?

A

sustentacular cells

22
Q

What do the interstitial cells (located outside of the seminiferous tubules) become?

A

Two different populations, one of them produces androgen hormones immediately, the other delays androgen production until sexual maturity

23
Q

What causes the paramesonephric ducts to regress in the seminiferous tubules?

A

they regress due to an inhibitory hormone produced by the sustentacular cells of the testis

24
Q

What does the cranial region of the mesonephric duct become?

A

It undergoes elongation and coiling to become epididymis

25
Q

What does the remaining region of the mesonephric duct become (not cranial)

A

Enlarges to become ductus deferens

26
Q

What do the female germ cells differentiate into?

A

they differentiate into primary oocytes

27
Q

What fails to develop in the absence of testosterone?

A

mesonephric ducts

28
Q

What does the cranial part of the paramesonephric duct become?

A

It stays open and becomes uterine tube

29
Q

What does the genital tubercle become in the male and female?

A

glans penis and clitoris

30
Q

What does the genital swelling become in the male and female?

A

Scrotum and labia majora

31
Q

What do the mesodermal cells next to the metanephrogenic mass grow and form?

A

Cell cords

32
Q

What happens to the cell cords after they are formed?

A

They canalise and elongate to become s-shaped metanephrogenic tubules