Development of The Foregut Flashcards
What is the foregut and what structures does it give rise to?
Foregut gives rise to esophagus, stomach, proximal duodenum, liver, gallbladder, pancreas, spleen, and respiratory system.
Describe the formation and significance of the stomodeum.
Stomodeum forms the primitive mouth and contributes to oral cavity development.
What is the role of the buccopharyngeal membrane in foregut development?
Buccopharyngeal membrane separates stomodeum from foregut, later ruptures to connect them.
Explain the formation and function of the respiratory diverticulum.
Respiratory diverticulum arises from foregut endoderm, forms respiratory tract.
What are the derivatives of the respiratory diverticulum?
Derivatives include trachea, bronchi, and lungs.
Describe the formation and significance of the esophagus during foregut development.
Esophagus forms from the elongation and differentiation of the foregut tube.
What is the origin of the epithelium lining the esophagus?
Epithelium is derived from endoderm.
Explain the development and function of the dorsal mesentery.
Dorsal mesentery suspends developing foregut structures from dorsal body wall.
What structures are suspended from the dorsal mesentery in the foregut region?
Suspended structures include esophagus, stomach, and proximal duodenum.
Describe the rotation and fixation of the stomach during development.
Stomach rotates clockwise, pulling duodenum and pancreas to the right.
What are the anatomical changes associated with the rotation of the stomach?
Rotation brings greater curvature leftward, lesser curvature rightward.
Explain the formation and function of the lesser omentum.
Lesser omentum connects lesser curvature of stomach to liver.
What structures does the lesser omentum connect?
Connects liver to lesser curvature of stomach and proximal duodenum.
Describe the development and function of the ventral mesentery.
Ventral mesentery forms lesser omentum and falciform ligament.
What structures are associated with the ventral mesentery in the foregut region?
Associated structures include liver and ventral pancreas.
Explain the significance of the hepatogastric and hepatoduodenal ligaments.
Ligaments connect liver to stomach and duodenum, respectively.
Describe the formation and function of the liver during foregut development.
Liver arises as outgrowth from foregut endoderm.
What are the primary sources of blood supply to the developing liver?
Blood supply comes from vitelline and umbilical veins.
Explain the formation and function of the bile duct system.
Bile duct system forms from hepatic diverticulum and hepatic duct.
What structures contribute to the formation of the bile duct system?
Contributions include hepatic duct, cystic duct, and common bile duct.
Describe the development and function of the pancreas during foregut development.
Pancreas develops from ventral and dorsal pancreatic buds.
What are the pancreatic buds, and what structures do they give rise to?
Buds give rise to exocrine and endocrine pancreas, respectively.
Explain the significance of the dorsal and ventral pancreatic buds.
Dorsal bud forms body and tail, ventral bud contributes to head.
Describe the fusion of the pancreatic buds during development.
Buds fuse to form main pancreatic duct system.
What are the primary ducts formed by the fused pancreatic buds?
Forms pancreatic duct and accessory pancreatic duct.
Explain the innervation of the foregut structures during development.
Innervation includes vagus and splanchnic nerves.
What are the main nerves involved in the innervation of the foregut?
Vagus nerve supplies parasympathetic innervation, splanchnic nerves supply sympathetic.
Describe the formation and function of the celiac artery.
Arises from abdominal aorta, supplies foregut structures.
What structures does the celiac artery supply in the foregut region?
Supplies stomach, duodenum, liver, pancreas, and spleen.
Explain the significance of the foregut derivatives in adult anatomy and physiology.
Foregut derivatives form essential components of digestion, respiration, and metabolism in adults.
