Demantia & Neurocognitive Flashcards
An acquired syndrome that results from a disease or disorder of the brain that affects cognition, or thinking, and memory. It disrupts perception, information processing, problem solving, judgment, sequencing of tasks, recognition and naming objects, mood and affect, writing and calculating, and other functions necessary to carry out daily activities
Dementia
The gradual or acute decline in abilities follows a predictable pattern:
Thinking: abstract thought to concrete processes to object centered
Memory: short-term memory impairment to long term memory impairment
Problem-solving: complex, high-impact decisions to inability to make simple decisions
Calculating: noticeable problems with complex math procedures to errors with simple calculations
Judgment: lack of awareness of factors in decision-making to inattention to problem- solving processes
Most common type of dementia
Alzheimer’s — age-related, neurological, degenerative
disorder that predominantly affects persons older than 65
Dementing diseases that can affect a person in mid to late life
Lewy body disease
Vascular or multi-infarct dementia
Frontotemporal lobe or Pick disease
Parkinson disease
Huntington disease
Normal pressure hydrocephalus
CONTRIBUTORS TO DEMENTIA
Creutzfeldt-Jakob disease (Mad Cow Disease)
HIV/AIDS-related dementia
Brain tumors
Brain trauma
Infectious diseases
Toxic exposures
Vitamin B12 deficiency
DEMENTIA SYMPTOMS IN YOUNGER ADULTS are Frequently due to the following:
Metabolic disorders
Substance abuse
Immune-mediated diseases
Infectious diseases
inability to learn new information and/or recall
past information
Memory impairment
absence or impairment of the ability to communicate
through speech, writing or signs because of brain dysfunction
Aphasia
inability to perform purposive movements although there is
no sensory or motor impairment
Apraxia
loss of comprehension of visual, auditory, or other sensations although sensory sphere is intact
Agnosia
ability to think abstractly and plan, initiate,
sequence, monitor, and stop complex behavior
Executive function
IN DSM 5, NEUROCOGNITIVE DISORDERS….
The grouping is unusual among the mental disorders because their etiology of each condition is specific and biological.
the term ‘neurocognitive’ describes cognitive functions closely linked to the functions of particular brain regions, neural pathways, or cortical/subcortical networks in the brain…parallel with the designations ‘neurocognitive,’ neuropsychology focuses on psychological processes and behaviors related to known structural or metabolic brain disease
the diagnostic criteria include disturbance in attention that
develops over a short time period, a change from the person’s normal state, and fluctuation over time . Disturbance in cognition is also evident
Global. Loss of cognitive func
The primary differences between the two are the rate of onset (rapid for delirium) and altered consciousness (characteristic of delirium but not dementia)
DELIRIUM
Most common in hospital or nursing home settings and among older adults
Almost always associated with a medical condition such as high fever, head injury, or as a postsurgical syndrome
Causes dysfunction in every occupation; disrupts habits, patterns, and roles
Impairs cognitive skill and attention
ETIOLOGY, PROGNOSIS & IMPLICATIONS FOR FUNCTION w/ delirium
Referred to as major NCD
Symptoms include significant cognitive decline from the previous level of performance in one or more cognitive domains based on concern of individual, an informant, or a clinician
Substantial impairment documented by neuropsychological or other quantifiable assessment, and the deficits interfere with independence in daily activities.
MAJOR NEUROCOGNITIVE DISORDER
Referred to as mild NCD
A modest cognitive decline from the previous level of performance in 1 or more cognitive domains; the deficits do not interfere with independence in daily activities, but greater effort, compensatory strategies, or accommodations may be required
Risk factors include genetic factors. Lower risk is associated with better visual acuity, mental activity, and odor identification. Increased risk: high homocysteine, heart disease, slow walk, hx of depression, and lack of challenging mental activity
MILD NEUROCOGNITIVE DISORDER
MAJOR NEUROCOGNITIVE DISORDER ETIOLOGICAL SUBTYPES
Alzheimer’s Disease (AD)
Frontotemporal Lobar Degeneration (FTLD)
Lewy Body Disease (LBD)
Vascular Disease
Traumatic Brain Injury (TBI)
Substance/Medication-Induced NCD
HIV Infection
Prion Disease
Parkinson’s Disease
Huntington’s Disease