Chapter 8- Blood and Immune System Flashcards
Blood
Fluid that circulates through the heart, arteries, capillaries, + veins, transporting oxygen and nutritive materials to the tissues
Formed elements
Blood cells
Plasma
Liquid portion of blood that carries formed elements, clotting factors, minerals, + proteins
Chrom/o, chromat/o
Color
Cyt/o
Cell
Erythr/o
Red
Granul/o
Granules
Anemia
Condition in which the number of red blood cells, hemoglobin, or volume of packed cells is lower than normal
Aplastic anemia
Disorder in which bone marrow does not produce enough RBCs
Iron deficiency anemia
Disorder in which hemoglobin is unable to transport oxygen due to a lack of iron
Pernicious anemia
Disorder in which the number of red blood cells decline with simultaneous enlargement of individual cells (i.e., macrocytes) due to an inability to absorb vitamin B-12; usually in older adults
Hemorrhagic anemia, syn. blood loss anemia
Disorder involving lack of red blood cells due to profuse blood loss
Thalassemia
Disorder caused by a genetic defect resulting in low hemoglobin production
Sickle cell anemia
Disorder caused by a genetic defect resulting in abnormal hemoglobin causing sickle-shaped red blood cells, which have difficulty moving through small capillary vessels
Autoimmune disease
Condition in which the immune system attacks normal body tissues
Clotting disorder
Condition characterized by an inability of blood to coagulate
Hemophilia
Bleeding disorder due to a deficiency of a clotting factor
Thrombocytopenia
Disorder involving low levels of platelets in blood
Idiopathic thrombocytopenic purpura (ITP)
Disorder marked by platelet destruction by macrophages resulting in bruising and bleeding from mucous membranes
Apheresis
Removal and replacement of a patient’s own blood or donor blood after specific components have been removed
Blood transfusion (BT)
Transfer of blood between compatible donor and recipient
Autologous blood
Blood donated for future use by same patient; usually presurgical
Homologous blood
Blood donated from same species for use by a compatible recipient
Blood component therapy
Transfusion of specific blood components such as packed red blood cells, plasma, or platelets
Allergology
Medical specialty concerned with diagnosis and treatment of allergy and sensitivity
Allergist
Physician who specializesin allergology
Hematology
Medical specialty concerned with diagnosis and treatment of disorders of the blood and blood-forming organs
Hematologist
Physician who specializes in hematology
Immunology
Medical specialty concerned w/ immunity, allergy, + induced sensitivity
Immunologist
One who practices immunology
Rheumatology
Medical specialty concerned w/ diagnosis and treatment of rheumatic conditions and autoimmune diseases
Rheumatologist
A physician who specializes in rheumatology
Platelet count
of platelets present; used to diagnose bleeding disorders or bone marrow disease
Red blood cell count (RBC)
Number of erythrocytes present; used to diagnose various disorders including anemia
Hem/o, hemat/o
Blood
Immun/o
Immune, safe
Leuk/o
White
Lymph/o
Lymph
Neutr/o
Neutral
Nucle/o
Nucleus
Path/o
Disease
Phag/o
Eat, swallow
Phleb/o
Vein
Plas/o
Formation, growth
Thromb/o
Blood clot
Auto-
Same, self
Basi-, baso-
Base
Macro-
Large, long
Micro-
Small
Mono-
One
Pro-
Before, promoting
Poly-
Many, much
-Cyte
Cell
-Emia
Blood (condition of)
-Sis
Condition, process
-Gen
Origin, production
-Lysis
Destruction, breakdown, separation
-Osis
Abnormal condition
-Penia
Deficiency
-Philia
Attraction for
-Poiesis
Production, formation
-Rrhage
Flowing forth
-Y
Condition of
Autoimmunity
Pertaining to one’s immune system attacking its own tissues or cells
Cytopathic
Pertaining to a disease or disorder of a cell or cellular component
Hematopoietic
Pertaining to the formation of blood cells
Hemolytic
Pertaining to the rupture or destruction of RBCs
Hemorrhagic
Pertaining to profuse or excessive bleeding
Hemostasis
Stoppage or arrest of bleeding
Hypersensitive
Condition of excessive response or an exaggerated sensitivity to a stimulus
Inflammatory
Pertaining to the process of heat, redness, swelling, + pain in response to tissue injury
Predisposition
Condition of being susceptible to disease
Proliferative
Growing or increasing in number of similar cells
Rejection
Immunologic response of incompatibility to a transplanted organ or tissue
Systematic
Pertaining to the body as a whole
Virulent
Denotes an extremely toxic pathogen
Hemoglobin (HGB, Hb, Hgb)
Protein in red blood cells that binds to oxygen; gives RBCs the characteristic color
Iron (Fe)
Essential trace element necessary for hemoglobin to transport oxygen on red blood cells
Macrocyte
Large red blood cell
Rh factor
Protein substance present in the red blood cells of most people (85%) capable of inducing intense antigenic reactions
Leukocyte, syn. white blood cell (WBC)
Largest blood cell; protects against pathogens, foreign substances, + cell debris
Granulocyte
White blood cell with visible granules; three types of granulocytes that are named according to the type of dye each is attracted to
Neutrophil
Type of granulocyte that fights against bacterial infections; stains a neutral pink
Eosinophil
Type of granulocyte that functions in allergic reactions and against parasites; stains red
Basophil
Type of granulocyte that releases histamine in allergic reactions and inflammatory responses; stains a dark blue with a basic dye
Agranulocyte
White blood cell without clearly visible granules
Fe
Iron
HCT, Hct, ht
Hematocrit
HGB, Hb, Hgb
Hemoglobin
ITP
Idiopathic thrombocytopenic purpura
PLT
Platelet or platelet count
PT
Orithrombin time
RA
Rheumatoid arthritis
RBC
Red blood cell; red blood cell count
SLE
Systemic lupus erythematosus
vWD
von Willebrand disease
WBC
White blood cell; white blood cell count
Ag
Antigen
ANA
Antinuclear antibody test
BMA
Bone marrow aspiration
BMT
Bone marrow transplant
BT
Blood transfusion
CBC
Blood transfusion
CBC
Complete blood count
C&S
Culture and sensitivity
ESV
Epstein-Barr virus
EPO
Erythropoietin
ESR
Erythrocyte sedimentation rate
Ab
Antibody
von Willebrand disease (vWD)
Bleeding disorder characterized by a tendency to bleed primarily from the mucous membranes due to a deficiency fo a clotting factor
Hemochromatosis
Excessive absorption and storage of dietary iron in body tissues causing dysfunction
Mononucleosis
Increase of mononuclear leukocytes with symptoms of fever, enlarged cervical lymph nodes, + fatigue
Lymphocyte
Type of agranulocyte that circulates in the lymphatic system and is active in immunity
B lymphocyte, syn. B cell
White blood cell that, when in contact with a foreign antigen, produces antibodies to inactivate the antigen
T lymphocyte, syn. T cell
White blood cell that matures in the thymus and specializes in creating an immune response
Monocyte
Largest form of white blood cells
Macrophage
Enlarged and matured monocytes active in phagocytosis
Thrombocyte, syn. platelet (PLT)
Cell fragments in the blood that stick together forming a clot
Clotting factors
Any of the various plasma components involved in the clotting process
Coagulation
Clotting; changing from a liquid to a solid state
Fibrin
Elastic fiber protein needed in clotting and produced by fibrinogen
Fibrinogen
Plasma protein that is converted into solid threads called fibrin
Antibody (Ab)
Soldier-like cell that protects the body and inactivates antigens; provides immunity against specific organisms
Antigen
Agent or substance that provokes an immune response
Histamine
Substance released by damaged cells that increase blood flow to the area, causing inflammatory process involving heat, redness, swelling, + pain
Immunity
Protection against disease
Pathogen
Any virus, microorganism, or other substance that causes disease
Phagocytosis
Cellular process of eating and destroying substances, usually by the neutrophils and macrophages
Pancytopenia
Deficiency in all types of blood cells
Polycythermia
Increase of red blood cells
Rheumatoid arthritis (RA)
Autoimmune disease causing progressive destructive changes and inflammation in multiple joints, especially in the hands and feet
Septicemia
Spread of microorganisms or toxins through circulating blood
Sjogren syndrome
Chronic autoimmune disease in which a person’s white blood cells attack their moisture-producing glands
Systemic lupus erythematosus (SLE)
Inflammatory, autoimmune, connective tissue disease that can affect all organ systems
Thrombosis
Abnormal presence of clotting within a blood vessel
Albumin
Measurement of this protein level; used to diagnose liver or kidney problems, inflammation, malnutrition, or dehydration
Bilirubin
Screen for liver disorders or anemia
Blood smear
Evaluation of the appearance and number of blood cells and the different types of white blood cells
Complete blood count (CBC), syn. hemogram
Automated count of all blood cells
Erythrocyte sedimentation rate (ESR)
Tume measurement of red blood cells settling in a test tube over 1 hour; used to diagnose inflammation and anemias
Hematocrit (HCT, Hct)
Volume of blood occupied by red blood cells; used to diagnose various disorders including anemia
Hemoglobin (HGB, Hgb, Hb) test
Test for the red blood cell protein responsible for binding oxygen used to diagnose various disorders including anemia
Splenectomy
Surgical removal of spleen
Plasmapheresis
Removal and replacement of a patient’s own blood after plasma has been removed and replaced with a plasma substitute
Phlebotomy, syn. venipuncture, venotomy
Incision into a vein to inject a solution or withdraw blood
Immunosuppression
Use of chemotherapy or immunosuppressant drugs to interfere with immune responses; usually prescribed for autoimmune disorders
Immunization, syn. vaccination
Administration of a weakened or killed pathogen, or a protein of a pathogen, to cause the immune system to produce antibodies for future protection
Bone marrow transplant (BMT)
Transfer of bone marrow from one person to another
Bone marrow aspiration (BMA)
Removal of a small amount of fluid and cells from inside the bone with a needle and syringe
Antibiotic
Drug that acts against susceptible microorganisms
Anticoagulant
Drug used to prolong blood clotting time
Antihistamine
Drug used to stop the effects of a histamine
Hemostatic agent, syn. procoagulant
Drug that stops the flow of blood within vessels
Immune serum
Serum prepared from an individual with specific disease antibodies
Immunosuppressant
Drug used to suppress or reduce immune responses in organ transplant recipients or those with severe autoimmune diseases
Thrombolytic agent
Drug that dissolves a blood clot
Vaccine
Preparation composed of a weakened or killed pathogen
White blood cell count (WBC)
Number of leukocytes present; used to diagnose various disorders including infections and diseases, + for monitoring treatment
Cross-matching
Blood typing test for compatibility between donor and recipient blood
Culture and sensitivity (C&S)
Growing of an organism from a specimen from the body to determine its susceptibility to particular medications
Prothrombin time (PT)
Measurement of time for blood to clot
WBC differential count, syn. differential count
Evaluation of the total percentage of leukocytes
Antinuclear antibody (ANA) test
Assessment for autoimmune disorders such as systemic lupus erythematosus, rheumatoid arthritis, + others
Epstein-Barr virus (EBV) antibody test
Diagnostic test for mononucleosis and evaluation of the Epstein-Barr virus
Mononucleosis spot test
Assessment for mononucleosis
Rheumatoid factor test
Test for rheumatoid arthritis and Sjogren syndrome