Chapter 16- Oncology and Cancer Terms Flashcards
Ablat/o
To take away
Bi/o
Life
Cancer/o, carcin/o
Cancer
Chem/o
Chemical, drug
Cry/o
Cold
Cyt/o
Cell
Kary/o
Nucleus
Lapar/o
Abdomen
Lei/o
Smooth
Leuk/o
White
Melan/o
Black, dark
Onc/o
Tumor
Path/o
Disease
Plas/o
Growth, formation
Radi/o
X-rays, radiation
Rhabd/o
Striated muscle
Sarc/o
Connective tissue, flesh
Squam/o
Scalelike structure
Dys-
Painful, difficult, abnormal
Intra-
Within
Mal-
Bad, poor
Meta-
Change, beyond
Neo-
New
Para-
Beside
Trans-
Across, through
-Gen
Origin, production
-Genic
Originating, producing
-Oma
Tumor
-Opsy
Process of viewing
-Scopy
Process of examining, examination
Benign
Nonmalignant form of a neoplasm
Cancer (CA)
General term for a group of diseases characterized by an abnormal, uncontrolled growth of cells
Cancerous
Pertaining to cancer
Carcinogen
Any cancer-causing substance or organism
Differentiation
Determination of how developed, or mature, the cancer cells are in a tumor
Dysplasia
Abnormal growth of tissue
In situ
In the original place or site without any expansion or spread
Invasion
Direct migration and penetration by cancerous cells into neighboring tissues
Lesion
A pathologic change in tissue resulting from a disease or injury
Malignant
Having the properties of locally invasive + destructive growth + metastasis
Metastasis
Spread of a disease process from one part of the body to another
Oncogenes
Mutated forms of genes that cause normal cells to grow out of control and become cancer cells
Oncogenic
Causing or being suitable for the development of a tumor
Recurrence
Return of cancer after all visible signs of it had been eradicated previously
Remission
Lessening in severity of disease symptoms; period of time when a cancer is responding to treatment or is under control
Adenocarcinoma
Malignant neoplasm composed of glandular tissue
Adenoma
Benign neoplasm composed of glandular tissue
Carcinoma
Malignant neoplasm of any epithelial tissue
Fibroma
Benign neoplasm of fibrous connective tissue
Fibrosarcoma
Malignant neoplasm of deep fibrous tissue
Lipoma
Benign neoplasm of adipose (fat) tissue
Liposarcoma
Malignant neoplasm of adipose (fat) tissue
Malignant neoplasm
Tumor that invades surrounding tissue and is usually capable of metastasizing; can be located in any organ or tissue of the body
Melanoma
Tumor characterized by a dark appearance; most commonly occurs in the skin or in the eye
Neoplasm, syn. tumor
Abnormal growth of a new tissue into a mass; can be benign or malignant
Neuroma
Tumor derived from nervous tissue
Myeloma
Tumor composed of cells derived from bone marrow
Sarcoma
Malignant neoplasm of connective tissue
Basal cell carcinoma (BCC)
Cancer that begins in the lowest layer of the epidermis of the skin
Kaposi sarcoma
Type of cancer found in the tissues under the skin or mucous membranes that line the mouth, nose, + anus; most commonly seen in patients w/ acquired immunodeficiency syndrome (AIDS)
Melanoma of the skin
Malignant skin cancer that arises from the melanocytes in the epidermis, usually caused by exposure to ultraviolet radiation
Squamous cell carcinoma (SCC)
Cancer that begins in the squamous cells located in the upper levels of the epidermis of the skin
Gastrointestinal stromal tumor (GIST)
Very rare cancer affecting the digestive tract or nearby structures within the abdomen
Malignant neoplasm of the bladder
Cancerous tumor of the bladder
Nephroma
Tumor of the kidney
Urothelial carcinoma, syn. transitional cell carcinoma
Cancer arising in the urothelium lining the urinary tract
Wilms tumor
Rare type of kidney cancer affecting children
Hodgkin disease
Abnormal malignant enlargement of lymph nodes, spleen, + liver; indicated by the presence of Reed-Sterberg cells
Leukemia
Cancer in the blood indicated by malignant increase in the number of white blood cells (WBCs)
Lymphangioma
Mass or tumor of lymph vessels
Lymphoma
Tumor of lymphoid tissue, including lymphocytes and plasma cells
Non-Hodgkin lymphoma (NHL)
Lymphoma other than Hodgkin disease
Bronchogenic carcinoma
Carcinoma that arises from the mucous of the large bronchi
Mesothelioma
A carcinoma of the mesothelium lining of the lungs or heart, usually associated with exposure to asbestos dust
Oat cell carcinoma
Highly malignant form of lung or bronchogenic cancer in which cells appear small and rounded under a microscope
Ductal carcinoma in situ (DCIS)
Breast cancer that is confined to the ducts and has not spread into the tissues of the breast
Germ cell tumor
Cancer that begins in the egg-producing cells of the ovaries
Stromal cell tumor
Cancer that begins in the cells of the ligaments of the ovaries
Astrocytoma
Tumor that arises from small, star-shaped cells in the brain and spinal cord
Glioma
Cancer that arises from the glial cells of the nervous system
Medulloblastoma
Cancer that develops from the primitive nerve cells in the cerebrum
Meningioma
Benign + slow-growing tumor of the meninges
Neuroblastoma
Cancer of the nervous system
Glomus tumor
A benign but locally invasive tumor arising out of glomus tissue found in the middle ear, jugular bulb, + carotid artery
Intraocular melanoma
Malignant cancer that forms in the tissues of the eye
Retinoblastoma
Malignant ocular tumor of retinal cells
Chondroma
Common benign tumor arising from cartilage cells
Chondrosarcoma
Large malignant tumor arising from cartilage cells
Ewing tumor, syn. Ewing sarcoma
Malignant tumor found in bone or soft tissue
Giant cell tumor
Tumor of the tendon sheath that can be either benign or malignant
Leiomyoma
Benign tumor of smooth (nonstriated) muscle
Leiomyosarcoma
Malignant tumor of smooth (nonstriated) muscle
Liposarcoma
Malignant tumor of adipose (fat) tissue; occurs in the retroperitoneal tissues and the thigh
Osteofibroma
Benign lesion of bone consisting chiefly of fairly dense, moderately cellular, fibrous connective tissue
Osteosarcoma
Fast-growing malignant type of bone cancer that develops in the osteoblast cells that form the outer covering of the bone
Rhabdomyoma
Benign tumor of striated muscle
Rhabdomyosarcoma
Highly malignant tumor of striated muscle
Multiple endocrine neoplasia (MEN)
Group of disorders characterized by functioning tumors in more than one endocrine gland
Pheochromocytoma
Vascular tumor of the adrenal gland
Pituitary adenoma
Benign tumor arising in the pituitary gland
Alpha fetoprotein (AFP)
Blood test for substance produced by tumor cells in the body; found in elevated levels in patients with ovarian cancer
Estrogen receptors
Blood test for a type of protein present on some breast cancer cells to which estrogen attaches
Human chorionic gonadotropin (hCG) test
Blood test for the substance that, in elevated levels, may indicate cancer in the testis, ovary, liver, stomach, pancreas, or lung
Papanicolaou (Pap) test
Microscopic examination of cells collected from the vagina and cervix to detect abnormal changes (ex: cancer)
Prostate-specific antigen (PSA)
Blood test for substance produced only by the prostate; elevated levels may indicate prostate cancer in its early stages
Tumor marker test
Various blood tests for specific substances produced by certain types of tumors
Biopsy
Process of removing tissue from living patients for diagnostic examination
Fine needle aspiration (FNA)
Procedure of withdrawing cells from a lesion for examination with a fine needle on a syringe
Radionuclide scan
Imaging scan in which a small amount of radioactive substance is injected into the vein; a machine measures levels of radioactivity in certain organs, which may indicate abnormal areas or tumors
Sentinel lymph node biopsy
Removal and examination of the sentinel nodes, which are the first lymph nodes to which cancer cells are likely to spread from a primary tumor
Single photon emission computed tomography (SPECT) scan
Type of nuclear imaging test that shows how blood flows to tissues and organs; can help identify certain types of tumors
Punch biopsy
Removal of a small oval core of skin for laboratory analysis using a sharp, hollow instrument
Shave biopsy
Removal of a sample of skin for laboratory analysis using a scalpel to slice the specimen from the site
Cholescintigraphy, syn. hepatobiliary iminodiacetic acid (HIDA) scan
Imaging test used to examine the function of the liver, gallbladder, + bile ducts
Endoscopic retrograde cholangiopancreatography (ERCP)
Procedure using x-ray and injectable dye to examine disorders in the bile ducts, gallbladder, + pancreas
Endoscopic ultrasound (EUS)
Procedure using an ultrasound imaging device on the tip of an endoscope for evaluation of the bowel wall and adjacent structures
Magnetic resonance cholangiopancreatography (MRCP)
Procedure using magnetic resonance imaging and an injectable dye to examine problems in the bile ducts, gallbladder, + pancreas
Lymph node biopsy
Removal of lymph node tissue for pathologic evaluation
Bone marrow aspiration
Removal of a small amount of fluid and cells from inside the bone with a needle and a syringe
Bone marrow biopsy
Removal and evaluation of a small amount of bone along with fluid and cells from inside the bone
Lumbar puncture (LP)
Process of inserting a needle into the subarachnoid space of the lumbar spine to obtain cerebrospinal fluid for analysis; used to determine if leukemic cells are present
Thoracoscopy, syn. pleuroscopy
Endoscopic examination of the thorax made through a small opening in the chest wall
Prostate biopsy
Procedure in which tissue samples are removed from the body for examination under a microscope to determine whether cancerous or other abnormal cells are present
Transrectal ultrasound (TRUS)
Ultrasound imaging of the prostate done through the rectum; used to diagnose prostate cancer
Cervical conization, syn. cone biopsy
Biopsy of cervix in which a cone-shaped sample of tissue is removed
Colposcopy
Visual examination of the tissues of the cervix and vagina using a lighted microscope (colposcope) to identify abnormal cell growth and, if necessary, remove a tissue sample for biopsy
Endometrial biopsy
Procedure whereby a sample of the endometrium of the uterus is removed from the body and examined under a microscope; used to check for uterine cancer
Mammography
An x-ray of the breasts; used to detect breast tumors
Brachytherapy, syn. seed implantation
Procedure by which radioactive “seeds’ are placed inside cancerous tissue and positioned to kill nearby cancer cells
Cryosurgery
Use of freezing temperatures to destroy tissue
Debulking surgery
Excision of a major part of a tumor that cannot be completely removed
Palliative surgery
Surgery that is performed to relieve pain or other symptoms but not to cure cancer or prolong a patient’s life
Radiofrequency ablation (RFA)
Procedure in which a surgical oncologist uses a small probe to deliver heat from radiofrequency energy to kill cancerous tissue; used primarily to treat liver, prostate, renal, bone, + breast cancer
Reconstructive surgery
Surgery performed to return function and appearance to a specific area of the body after the removal of a tumor
Mohs surgery
Surgical procedure that involves removing and examining a piece of tumor in the skin bit by bit until the entire lesion is removed
Colectomy
Excision of all or part of the colon
Esophagectomy
Excision of the diseased portion of the esophagus and all associated tissues that might contain cancer
Gastrectomy, syn. Billroth operation 1 and 2
Excision of part or all of the stomach
Pancreaticoduodenectomy, syn. Whipple operation
Partial excision of the stomach, complete excision of the gallbladder, a portion of the bile duct, head of the pancreas, portions of the small intestine, + regional lymph nodes to stop the spread of cancer in these areas
Cystectomy
Surgical removal of part or all of the bladder
Fulguration
Destruction of tissue by means of high-frequency electric current; commonly used to remove tumors from inside the bladder
Nephrectomy
Excision of a kidney
Transurethral resection of bladder tumor (TURB)
Excision of a tumor from the bladder through the urethra using a resectoscope
Lymphadenectomy
Excision of a lymph node
Bone marrow transplant (BMT)
Transfer of bone marrow from one person to another
Peripheral stem cell transplant
Collection and freezing of stem cells from the blood, which are then reintroduced into the patient after chemotherapy
Lobectomy
Excision of a lobe (of the lung)
Pneumonectomy
Excision of the lung
Wedge resection
Excision of part of a lobe of the lung
Prostatectomy, syn. transurethral resection of the prostate (TURP)
Removal of prostate tissue through the urethra using a stethoscope
Loop electrosurgical excision procedure (LEEP)
Gynecologic procedure that uses a thin, low-voltage electrified wire loop to cut out cancerous tissue in the cervix
Mastectomy
Excision of a breast to remove a malignant tumor
Modified radical mastectomy
Excision of a breast along with some of the underlying muscle and lymph nodes in the adjacent armpit
Radical mastectomy
Excision of the breast as well as the underlying muscles and lymph nodes in the adjacent armpit
Simple mastectomy
Excision of a breast, leaving the underlying muscles and lymph nodes intact
Myomectomy
Excision of myomas
Craniectomy
Excision of part of the cranium to access the brain
Stereotactic radiosurgery
Radiation therapy technique for treating brain tumors by aiming high-dose radiation beams directly at the tumors
Enucleation
Removal of an eyeball
Iridectomy
Excision of part of the iris (for very small melanomas)
Laryngectomy
Excision of part or all of the larynx, usually to treat cancer
Amputation
Surgical removal of an entire limb
Limb salvage surgery
Surgical procedure in which only the cancerous section of bone is removed but nearby muscles, tendons, and other structures are left intact
Parathyroidectomy
Excision of a parathyroid gland
Thyroidectomy
Excision of the thyroid gland
Transsphenoidal resection
Excision of a pituitary adenoma by making an incision through the nose to the bottom of the skull where the pituitary gland is located
External beam radiation
Procedure by which a beam of high-energy radiation is applied externally directly to the tumor to minimize damage to other tissues
Radiation therapy
The use of high-energy x-rays or other particles to kill cancer cells
Aromatase inhibitors
Group of drugs designed to reduce estrogen levels in a woman’s body and stop the growth of cancer cells that depend on estrogen to live/grow
Chemoprevention
Use of natural or synthetic products to keep cancer at bay or stop the disease process before it becomes invasive
Chemotherapy
Regimen of therapy using chemicals to treat cancer
Adjuvant chemotherapy
Chemotherapy given in addition to surgery, to destroy remaining residual tumor or to reduce the risk of recurrence
Interstitial chemotherapy
Placement of chemotherapy drugs directly into a tumor
Intrathecal chemotherapy
Delivery of chemotherapy drugs into the spinal canal
Palliative chemotherapy
Chemotherapy that is given to relieve pain or other symptoms of cancer but not to cure it
Epidermal growth factor receptor (EGRF) inhibitor therapy
Drugs that interfere with the growth of individual cancer cells
Hormonal therapy
Use of hormones to stop a tumor from growing, to relieve symptoms caused by a tumor, or to replace the hormone that is needed by the body to function properly after a body part is removed due to cancer
Immunotherapy, syn. biologic therapy
Method of boosting the body’s natural defenses to fight cancer by using materials made either by the body or in a laboratory to bolster, target, or restore immune system function
Gynecologic oncology
Medical specialty concerned with the diagnosis and treatment of cancers of the female reproductive system
Gynecologic oncologist
Physician who specializes in the care and treatment of women with gynecologic cancers
Medical oncology
Medical specialty concerned with the use of medical and chemotherapeutic treatments of cancer
Medical oncologist
Physician who specializes in the science of oncology
Pediatric oncology
Medical specialty concerned with the diagnosis and treatment of childhood cancers and blood diseases
Pediatric oncologist
Physician who specializes in the treatment of childhood cancers and blood diseases
Radiation oncology
Radiologic specialty concerned with radiation treatment as the main mode of treatment for cancer
Radiation oncologist
Physician who specializes in treating cancer with high-energy e-rays to destroy cancerous cells
Surgical oncology
Surgical specialty concerned with the surgical aspects of cancer
Surgical oncologist
Physician who specializes in the surgical aspects of cancer, including biopsy and tumor staging and resection
AFP
Alpha fetoprotein
BCC
Basal cell carcinoma
BMT
Bone marrow transplant
CA
Cancer
DCIS
Ductal carcinoma in situ
EGFR
Epidermal growth factor receptor
ERCP
Endoscopic retrograde cholangiopancreatography
EUS
Endoscopic ultrasound
FNA
Fine needle aspiration
GIST
Gastrointestinal stromal tumor
hCG
Human chorionic gonadotropin
HIDA
Hepatobiliary iminodiacetic acid
LEEP
Loop electrosurgical excision procedure
LP
Lumbar puncture
MEN
Multiple endocrine neoplasia
MRCP
Magnetic resonance cholangiopancreatography
NHL
Non-Hodgkin lymphona
PSA
Prostate-specific antigen
FRA
Radiofrequency ablation
SCC
Squamous cell carcinoma
SPECT
Single photon emmision computed tomography
TRUS
Transrectal ultrasound
TURB
Transurethral resection of bladder tumor
TURP
Transurethral recetion of prostate