Chapter 4: Integumentary System Flashcards
What are the two components if the integumentary system?
- ) Cutaneous Membrane
2. ) Accessory Structures
What are the functions of the integumentary system?
- ) protects deeper tissues (see slide for all)
- ) aids in heat regulation
- ) aids in excretion of urea and uric acid
- ) Synthesizes vitamin D
What are 4 epidermis characteristics?
- ) Stratified squamous epithelium
- ) Lacks blood vessels but can divide
- ) As new cells grow, push older ones to surface
- ) Outer most layer is dead
What are the 4 Epidermal cell types?
Keratinocytes
Melanocytes
Langerhan cells
Merkel cells
What do Keratinocytes do? What percent of epidermal cells are keratinocytes?
produce keratin and provide protection
90%
Where do langerhan cells come from? what system are they in?
bone marrow; immune system
what do merkel cells do?
form touch receptors with sensory neuron
_______ cells divide to produce _________ at the __________
stem; keratinocytes; basal lamina
As Keratinocytes are pushed up towards to surface they…… (2 things)
- fill with keratin and oils
- slowly die
How long is a keratinocytes journey?
4 weeks unless outer layers removed by abrasion
What are the five layers of epidermis?
- ) stratum germinativum
- ) stratum spinosum
- ) stratum granulosum
- ) stratum lucidum
- ) stratum corneum
what layer of cells is the stratum germinativum?
what cells make up this stratum?
what do they attach to and by what?
- Deepest single layer of cells
- Combination of merkel cells, melanocytes, keratinocytes, and stem cells that divide repeatedly
- cells attached to each other and to basal lamina by desmosomes and hemidesmosomes
What two layers does the stratum germinativum connect?
dermis and epidermis
How many cell layers thick is the stratum spinosum?
8-10
What happens in the stratum spinosum?
melanin taken in by phagocytes from nearby melanocytes. During slide preparation, cells shrink and look spiny
How many layers thick is the stratum granulosum?
are these cells dead or alive
3-5 layers of flat dying cells
What does the stratum granulosum contain and why is this important?
It contains dark-staining keratohyalin granules. This is important because these granules release lipid that repels water. It makes the cells oily so water can’t come in or out
**so skin can’t go bad (butter analogy)
Where is the stratum lucidum located?
How many layers of cells?
seen in thick skin on palms and soles of feet only
3-5 layers of clear, flat, dead cells
How many layers thick is the stratum corneum? describe the cells in these layers
25-30 layers of flat dead cells filled with keratin and surrounded by lipids
What is the purpose of the stratum corneum?
barrier to light, heat, water, chemicals, and bacteria (protection)
friction of the stratum corneum stimulates ________ formation
callus
give 3 characteristics of thick skin?
- palmer and planter surface
- about 30 layers of stratum corneum
- all 5 layers
give 3 characteristics of thin skin
- rest of body surfaces
- fewer layers of stratum corneum
- no stratum lucidum
what is another name for fingerprints?
epidermal ridges
what stratum forms these ridges that extend into the dermis?
germinativum
Why are epidermal ridges important?
they increase the surface area and friction therefore increasing the grip in hands and also in feet
melanocytes release vesicles called ___________ into keratinocytes
melanosomes
True or False:
Everyone has a similar number of melanocytes
true
the amount of pigment produces by melanocytes is determined by 2 factors……
- ) genetic control
2. ) respond to melanocyte stimulating hormone