Chapter 34: Neurons and Nervous Systems Flashcards
neurons
nerve cells
glia
glial cells
cell body [of a neuron]
the nucleus and most organelles
where the typical cell ish stuff is found
dendrites
likes tree branches
trees
bring info from other sources to the cell body, like the branches bring the products of photosynthesis to the trunk [but not really]
excitable
neurons create and send electrical signals, which makes them excitable
T or F: Neurons are excitable
true
axon
a tail like projection that can be freakishly long, like almost as long as you are tall long.
telephone lines of the nervous systems
generate the action potentials, which will travel down the axon
nerve
a bundle of axons that come from tons of neurons
axon terminal
a bump like thing at the end of the axon that is super duper close to the target cell, forming a synapse
synapse
tiny gap across which two neurons communicate, either electrically or chemically [neurotransmitters]
presynaptic neuron
neuron that sends the signal
postsynaptic neuron
neuron that receives the signal
Astrocytes
Glia that surround the smallest, most permeable blood vessels that help prevent toxic chemicals from entering
Neuroplasticity
Synapse modification
Glia play a role in that
Glia
Don’t generate action potentials
Can release neurotransmitters
Support developing neurons during embryonic development
Maintain extra cellular environment and provide energy substrates
Assist in neuronal repair
Blood-brain barrier
Prevents toxic chemicals and ether soluble/large molecules from reaching the brain
Microglia
Provide the brain with immune with defenses
Act as macrophages and mediators of immune responses
Oligodendrocytes
Glia in brain and spinal cord
Their membranes insulate axons
Schwann cells
A type of glia
Insulate axons outside the brain and spinal cord with their membranes
Myelin
A lipid rich no conductive sheath formed by the multilayered wrap of glial membranes
White matter
Parts of the nervous system consisting of misty myelinated axons
Gray matter
Areas of the nervous system that are rich in cell bodies
Multiple sclerosis
Demyelinating disease
Autoimmune disease in which antibodies attack proteins in the myelin
Neural networks
Information processing systems that neurons are organized into
Afferent neurons
Carry sensory info to nervous system
Sensory cells
Convert sensory stimuli into action potentials
Efferent neurons
Carry command to physiological and behavioral effectors like muscles and glands
Motor neurons
Type of effector neuron that carry commands to muscles
Interneurons
Integrate and store information and communicate between afferent and efferent
Ganglia
Clusters of neurons
Membrane potential
The difference in electrical potential across plasma membranes
Action potentials
Nerve impulses
large, sudden, and transient changes in membrane potential that travel alone axons and prompt the release of chemical signals at the axon terminals
Voltage
a measure of the difference in electrical charge between two points
potential energy
opposite charges will move together if given a chance
Is this an example of voltage difference?
Negative and positive poles of a battery are connected by a wire and an electric current flows through them [because of the possible voltage difference]
Yes
Membrane potential
a voltage across the cell membrane, caused by differing concentrations of ions on the outside and inside of the cell
Resting Potential
the membrane potential in an inactive neuron
What is the typical resting potential in a cell?
between -60 and -70 millivolts
True or false: The inside of the cell is electrically negative compared with the outside
True
True or False: Action Potential causes the inside of the cell to become more positive
True
sodium-potassium pump
aka sodium-potassium ATPase
Sends Na+ out of the cell because it has no need for excessive amounts of positivity and brings in smaller amounts of K+
True or False: K+ and Na+ are the predominant ions in the extracellular fluid
false: Na+ and Cl- are the predominant ions in the extracellular fluid, K+ is more prevalent inside of the cell
If Na+ could follow its concentration gradient, it would move __________ of the cell?
inside, K+ would leave
True or false: concentration gradients generate resting potential
true
True or false: concentration gradients can change resting potential
true
Would you notice a voltage difference between electrodes placed in two places outside of a resting neuron?
nope, the difference lies between outside and inside of the cell
What is the voltage difference between the outside and inside of neurons caused by?
leak currents
Leak currents
occur because there are open channels which embrace the spirit of heyyyy let’s be inclusive and let everyone in/out you do you ion
K+ leakage
one of the leakiest
K+ diffuses outside of the membrane until the negative charge of the cell pulls it back
Electrochemical gradient
combination of the concentration gradient of the ion and the overall electric gradient of the cell
Equilibrium potential
of ions
no net movement
ex. K+ with an electrochemical gradient of 0 in a neuron
Voltage-gated channels
open or close in response to local changes in voltage across membrane
Chemically gated channels
open or close in response to certain molecules
Mechanically gated channels
open or close based on the mechanical force applied to the cell membrane
depolarized
ex. when neuron becomes more positive due to the influx of sodium ions
hyperpoalrized
neuron becomes more negative due to the influx of potassium ions
graded membrane potentials
small, local changes in membrane potential that vary in magnitude
integrate inputs in a cell
look at sum of all of the depolarizing and hyper polarizing
spreads quickly but decays as it spreads like water through leaky hose
True or False: graded membrane potentials can carry a signal all the way down an axon
false, only action potentials do this
axon hillock
region of the cell body at the base of the axon
high concentration of Na+ gates
must let in enough Na+ in order to reach the threshold for the neuron to fire
refractory period
Na+ gated channels can not open again
prevent signal form going backwards
all-or-nothing
DESCRIBES ACTION POTENTIALS oops caps lock
either firing or isn’t, no different rates
Why all-or-nothing?
positive feedback loop for Na+ gated channels
`self-regenerating
spread by local current to neighbors
describe axon potentials
all-or-nothing self-regenerating
True or False: Action potentials travel along all axons at the same speed
False
True or False: Action potentials fire faster with long diameter
true
myelination
glia wrap themselves around axons
nodes of Ranvier
unmyelinated gaps
saltatory conduction
action potentials jump from node to node
chemical synapse
most common type
neurotransmitters are released from presynaptic cell and bind to receptors in postsynaptic cell, causing a change
Synaptic Cleft
space between presynaptic and postsynaptic cell
Electrical Synapses
join cytoplasms of pre and post synaptic cells through GAP Junctions
Gap Junctions
made up of proteins that create channels
ions flow through these allowing a passive spread of action potential
Pro: fast transmission
Con: don’t allow for complicated integration from many different sources