Chapter 26: Coagulation Modifier Drugs

Question 1

educate patients about bleeding precautions: electric razor for shaving, soft toothbrush, monitor for bleeding, avoid NSAIDS and ASA

Answer 1

anticoagulants (heparin, enoxaparin, warfarin)

Question 2

route of administration of warfarin

Answer 2

oral

Question 3

obtain baseline lab work prior to starting the drip

Answer 3

heparin

Question 4

this antiplatelet drug is used only as IV

Answer 4

eptifibatide

Question 5

drug class that primarily prevents arterial clots

Answer 5

antiplatelets

Question 6

prolongs clotting time

Answer 6

warfarin

Question 7

used to prevent DVT and acute PE after orthopedic or abdominal surgery

Answer 7

enoxaparin

Question 8

used in patients with a higher risk for clotting due to venous or arterial disorders

Answer 8

anticoagulants

Question 9

prevents thrombi from growing larger in acute thrombosis

Answer 9

heparin

Question 10

degrades fibrinogen, fibrin, and other clotting factors disintegrating clot

Answer 10

thrombolytics

Question 11

prevents venous thrombosis

Answer 11

heparin

Question 12

drug class that attacks and dissolves blood clots that have already formed

Answer 12

thrombolytics

Question 13

drug class that primarily prevents venous clots

Answer 13

anticoagulants

Question 14

the goal of INR for warfarin therapy is _____

Answer 14

2.0-3.0

Question 15

drug that inactivates Xa factor, decreasing ability to inactivate thrombin

Answer 15

enoxaparin

Question 16

When taking anticoagulants, hold dose and notify provider if _____ exceeds therapeutic range.

Answer 16

INR

Question 17

drug that inhibits clot formation by inhibiting action of thrombin, which inhibits conversion of fibrinogen to fibrin

Answer 17

heparin

Question 18

inhibits hepatic synthesis of vitamin K, thus affecting clotting factors II, VII, IX, and X

Answer 18

warfarin

Question 19

drug class that prevents the formation of clots and does not dissolve clots already formed

Answer 19

anticoagulants

Question 20

example of foods high in vitamin K

Answer 20

dark green leafy vegetables

Question 21

used to PREVENT COMPLICATIONS in certain types of MI

Answer 21

enoxaparin

Question 22

contraindicated in patients with strokes, peptic ulcers, and blood anomalies

Answer 22

enoxaparin

Question 23

binds to fibrin promoting conversion of plasminogen to plasmin

Answer 23

thrombolytics

Question 24

prevents MI, reinfarction following acute MI, and ischemic stroke

Answer 24

antiplatelets

Question 25

used to treat DIC

Answer 25

heparin

Question 26

monitor for therapeutic ranges of prothrombin time (PT) and international normalized ration (INR)

Answer 26

warfarin

Question 27

three side effects of warfarin

Answer 27

hemorrhage hepatitis overdose/toxicity

Question 28

SERIOUS risk of bleeding from internal and superficial sites

Answer 28

thrombolytics

Question 29

can be given at home; aPTT monitoring not necessary

Answer 29

enoxaparin

Question 30

two side effects of heparin

Answer 30

hemorrhage heparin-induced thrombocytopenia

Question 31

this drug has multiple medication interactions: collect thorough medication history

Answer 31

warfarin

Question 32

contraindicated with hemorrhagic stroke and active internal bleeding

Answer 32

thrombolytics

Question 33

this drug requires dosage check with another nurse before administration

Answer 33

heparin

Question 34

route of administration of enoxaparin and location

Answer 34

subcutaneously in abdomen

Question 35

two routes of administration of heparin

Answer 35

subcutaneous, intravenous (poorly absorbed in GI tract)

Question 36

treats PE, DVT, and thrombolytic stroke

Answer 36

thrombolytics

Question 37

educate clients taking warfarin to avoid large amounts of or maintain a consistent intake of _____________ and avoid fluctuations in intake that could impact warfarin action

Answer 37

vitamin K

Question 38

used for intermittent claudication

Answer 38

antiplatelets

Question 39

prevents MI, PE, and DVT

Answer 39

warfarin

Question 40

treats venous thrombosis and thrombus in clients with AFib or prosthetic heart valves

Answer 40

warfarin

Question 41

For warfarin overdose, ________ mg of ___________ is given (slowly, fast) via ___________. Once given, it causes warfarin resistance for _______.

Answer 41

5-10, phytonadione (vitamin K), slowly, IV infusion, 7 days

Question 42

drug class that prevents platelets from clumping together and inhibits platelet aggregation at onset of clotting process

Answer 42

antiplatelets

Question 43

has a lower risk of bleeding than heparin

Answer 43

enoxaparin

Question 44

requires serum monitoring of partial thromboplastin time (PTT) and activated partial thromboplastin time (aPTT)

Answer 44

heparin