Chapter 26: Coagulation Modifier Drugs Flashcards

1
Q

educate patients about bleeding precautions: electric razor for shaving, soft toothbrush, monitor for bleeding, avoid NSAIDS and ASA

A

anticoagulants (heparin, enoxaparin, warfarin)

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2
Q

route of administration of warfarin

A

oral

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3
Q

obtain baseline lab work prior to starting the drip

A

heparin

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4
Q

this antiplatelet drug is used only as IV

A

eptifibatide

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5
Q

drug class that primarily prevents arterial clots

A

antiplatelets

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6
Q

prolongs clotting time

A

warfarin

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7
Q

used to prevent DVT and acute PE after orthopedic or abdominal surgery

A

enoxaparin

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8
Q

used in patients with a higher risk for clotting due to venous or arterial disorders

A

anticoagulants

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9
Q

prevents thrombi from growing larger in acute thrombosis

A

heparin

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10
Q

degrades fibrinogen, fibrin, and other clotting factors disintegrating clot

A

thrombolytics

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11
Q

prevents venous thrombosis

A

heparin

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12
Q

drug class that attacks and dissolves blood clots that have already formed

A

thrombolytics

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13
Q

drug class that primarily prevents venous clots

A

anticoagulants

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14
Q

the goal of INR for warfarin therapy is _____

A

2.0-3.0

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15
Q

drug that inactivates Xa factor, decreasing ability to inactivate thrombin

A

enoxaparin

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16
Q

When taking anticoagulants, hold dose and notify provider if _____ exceeds therapeutic range.

A

INR

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17
Q

drug that inhibits clot formation by inhibiting action of thrombin, which inhibits conversion of fibrinogen to fibrin

A

heparin

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18
Q

inhibits hepatic synthesis of vitamin K, thus affecting clotting factors II, VII, IX, and X

19
Q

drug class that prevents the formation of clots and does not dissolve clots already formed

A

anticoagulants

20
Q

example of foods high in vitamin K

A

dark green leafy vegetables

21
Q

used to PREVENT COMPLICATIONS in certain types of MI

A

enoxaparin

22
Q

contraindicated in patients with strokes, peptic ulcers, and blood anomalies

A

enoxaparin

23
Q

binds to fibrin promoting conversion of plasminogen to plasmin

A

thrombolytics

24
Q

prevents MI, reinfarction following acute MI, and ischemic stroke

A

antiplatelets

25
used to treat DIC
heparin
26
monitor for therapeutic ranges of prothrombin time (PT) and international normalized ration (INR)
warfarin
27
three side effects of warfarin
hemorrhage hepatitis overdose/toxicity
28
SERIOUS risk of bleeding from internal and superficial sites
thrombolytics
29
can be given at home; aPTT monitoring not necessary
enoxaparin
30
two side effects of heparin
hemorrhage heparin-induced thrombocytopenia
31
this drug has multiple medication interactions: collect thorough medication history
warfarin
32
contraindicated with hemorrhagic stroke and active internal bleeding
thrombolytics
33
this drug requires dosage check with another nurse before administration
heparin
34
route of administration of enoxaparin and location
subcutaneously in abdomen
35
two routes of administration of heparin
subcutaneous, intravenous (poorly absorbed in GI tract)
36
treats PE, DVT, and thrombolytic stroke
thrombolytics
37
educate clients taking warfarin to avoid large amounts of or maintain a consistent intake of _____________ and avoid fluctuations in intake that could impact warfarin action
vitamin K
38
used for intermittent claudication
antiplatelets
39
prevents MI, PE, and DVT
warfarin
40
treats venous thrombosis and thrombus in clients with AFib or prosthetic heart valves
warfarin
41
For warfarin overdose, ________ mg of ___________ is given (slowly, fast) via ___________. Once given, it causes warfarin resistance for _______.
5-10, phytonadione (vitamin K), slowly, IV infusion, 7 days
42
drug class that prevents platelets from clumping together and inhibits platelet aggregation at onset of clotting process
antiplatelets
43
has a lower risk of bleeding than heparin
enoxaparin
44
requires serum monitoring of partial thromboplastin time (PTT) and activated partial thromboplastin time (aPTT)
heparin