Chapter 22: Antihypertensives Flashcards

1
Q

this side effect of ACE inhibitors can remain 2-3 months after discontinuation

A

loss of taste

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2
Q

most commonly used alpha2 receptor agonist

A

clonidine

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3
Q

two calcium channel blockers that can be used for dysrhythmias

A

verapamil
diltiazem

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4
Q

three uses of all calcium channel blockers

A

angina
hypertension
Raynaud’s disease

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5
Q

specific drug most frequently prescribed for hypertension

A

hydrochlorothiazide

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6
Q

this drug class works best in African American populations

A

calcium channel blockers

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7
Q

with all hypertensives, avoid abrupt _____________, which can cause ______________________

A

discontinuation, rebound hypertension

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8
Q

this angiotensin II receptor blocker (ARB) is used for those with an increased risk for stroke

A

losartan

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9
Q

drug class: can also be used for benign prostatic hyperplasia

A

alpha1 blockers (doxazosin, prazosin, terazosin)

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10
Q

drug class: avoid all supplements with potassium unless prescribed

A

ACE inhibitors

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11
Q

drug class: excretes Na and H2O and retains potassium

A

ACE inhibitors

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12
Q

drug class: do not work well in African Americans unless combined with a diuretic

A

beta blockers

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13
Q

drug class: adverse effects include chest pain, fatigue, hypoglycemia, diarrhea, UTIs, anemia, and weakness

A

angiotensin II receptor blockers (ARBs)

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14
Q

drug class: avoid using with NSAIDs due to decreased medication effectiveness and increased risk for renal failure

A

ACE inhibitors

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15
Q

two uses of angiotensin II receptor blockers (ARBs)

A

hypertension
adjunct therapy for heart failure

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16
Q

drug class: monitor for weight gain related to fluid retention

A

beta blockers

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17
Q

block calcium channels in vascular smooth muscle cells promoting vasodilation

A

calcium channel blockers

18
Q

specific drug: treats hypertension in pregnancy

A

methyldopa

19
Q

this calcium channel blocker drug prevents cerebral artery spasms occurring in subarachnoid hemorrhage

A

nimodipine

20
Q

hypertension drug class of choice for diabetics due to protective effect on kidney

A

ACE inhibitors

21
Q

drug class: stops the progression of ventricular hypertrophy after an MI

A

ACE inhibitors

22
Q

three common side effects of adrenergic drugs

A

impotence
postural/orthostatic hypotension
depression

23
Q

notify MD if SBP is <___ or HR <____ before administering beta blockers

A

90, 60

24
Q

two drug classes that do not work well/are less effective in blacks/African Americans

A

ACE inhibitors
beta blockers

25
Q

drug class: not recommended for renal insufficiency (creatine clearance below 30 mL/min)

A

thiazide diuretics

26
Q

drug class: contraindicated in pregnancy and breast-feeding mothers

A

angiotensin II receptor blockers (ARBs)

27
Q

nonselective blockers are also known as

A

alpha1 and beta1 blockers

28
Q

four OTHER side effects of ACE inhibitors

A

hyperkalemia
fatigue
mood changes
renal failure
(dry cough, loss of taste covered on other cards)

29
Q

main side effect of ACE inhibitors that is reversible with medication discontinuation

A

dry, nonproductive cough

30
Q

drug class: inhibit beta1 and beta2 receptors (affect both heart and lungs)

A

alpha1 and beta1 blockers

31
Q

drug class: not typically prescribed as first-line treatment for hypertension due to high incidence of side effects

A

alpha2 receptor agonists

32
Q

three uses of ACE inhibitors

A

hypertension, heart failure, post MI

33
Q

drug class: inhibit formation of angiotensin II from angiotensin I (causes vasodilation)

A

ACE inhibitors

34
Q

before administering antihypertensives, check _____________ and _____________

A

blood pressure, heart rate

35
Q

drug class: mainly blocks beta1 receptors

A

cardio selective beta blockers

36
Q

four side effects of calcium channel blockers

A

ankle edema
bradycardia
dizziness
AV block

37
Q

drug class: block angiotensin II from angiotensin I receptors

A

angiotensin II receptor blockers (ARBs)

38
Q

two drug classes that decrease cardiac contractility (use with caution in heart failure; monitor for signs and symptoms of heart failure)

A

beta blockers
calcium channel blockers

39
Q

two drug classes that reduce blood pressure by reducing heart rate (drop both)

A

cardio selective beta blockers
alpha1 and beta1 blockers

40
Q

three side effects of alpha2 receptor agonists

A

orthostatic hypotension
dizziness
fatigue

41
Q

specific drug that cannot be abruptly stopped due to severe rebound hypertension

A

clonidine