Chapter 21: Genitourinary Infections-Part 1 Flashcards
United States leads Industrialized nations in reported incidence of..
Sexually transmitted infections
Normally urine and urinary tract above bladder entrance are…
Free of microorganisms (sterile)
Lowe urethra contains..
Normal resident flora
Species of normal resident flora of the urethra include..
Lactobacillus, Staphylococcus, Corynebacterium and Streptococcus
Normal flora and resistance to infection varies considerably in female genital tract. This depends considerably on..
Hormonal status
UTIs account for around ________ doctor visits annually in the US
7 million
UTIs may account for ___ or ___ of the organs of the urinary system
Any
All
Any situation interfering with urine flow…
Increases risk of infection
3 types of bacteria that can cause UTIs
Escherichia coli
Staphylococcus saprophyticus
Proteus mirabillis
Cystitis
Bladder infection
Pyelonephritis
Kidney infection
E coli mode of transmission
Endogenous transfer from GI tract
Staphylococcus saprophyticus mode of transmission
Opportunism
Proteus mirabillis mode of transmission
Opportunism
Vulvovaginal Candidiasis
Vaginal yeast infection
Vulvovaginal Candidiasis symptoms
Itching
Burning
Scant vaginal discharge (white clumps)
Involved area usually red or swollen
Causative agent of Vulvovaginal candidiasis
Candida albicans
YEAST
Candida albicans is part of the normal flora in approximately ___% of women
35
Vulvovaginal candidiasis normally causes no symptoms because..
Of the balance between etiologic organism and normal vaginal flora
Yeast infections occur when….
Balance upset fungi, multiply without restraint, cause inflammatory response and symptoms
Spread of vulvovaginal candidiasis
Disease not spread person to person
Generally not sexually sexually transmitted
Vulvovaginal candidiasis: antibacterial medications….
Increase risk of disease
Prevention of vulvovaginal candidiasis
Prevention directed at minimizing use and duration of antibiotic therapy
Treatment of vulvovaginal candidiasis
Intravaginal treatment with anti-fungal medication usually effective
OTC medications for treatment of Vulvovaginal candidiasis
Nystatin and Clotrimazole (most effective)
Common prescription medication for Vulvovaginal candidiasis
Fluconazole given by mouth
1 in 7 have side effects
Gonorrhea incubation period
2 to 5 days post exposure
Gonorrhea: _______ infection can occur on both sexes
Asymptomatic
Gonorrhea symptoms men
Characterized as urethritis with
- Pain on urination
- Discharge from penis
Gonorrhea symptoms women
Painful urination
Mild discharge
Are men or women more likely to be asymptomatic carriers of gonorrhea?
Women
Gonorrhea causative agent
Neisseria gonorrhoeae
Characteristics of Neisseria gonorrhoeae
Gram negative
Diplococcus
Neisseria gonorrhoeae is typically found
On or in leukocytes or in urethral pus
Do most Neisseria gonorrhoeae survive well outside of host?
No
Neisseria gonorrhoeae infects..
Only humans
Gonnorhea bacteria is transmitted primarily by…
Intimate sexual contact
Neisseria gonorrhoeae attach to..
Non-ciliated epithelial cells via pili
Neisseria gonorrhoeae attach particularly to cells of the..
Urethra, uterine cervix and conjunctiva
Neisseria gonorrhoeae proteins bind…
CD4 lymphocytes (prevents activation of immune response)
_______ _______ allows gonorrheal escape from antibody
Antigenic variation (interferes with ability to make vaccine)
In women, gonorrhea follows a different course. The organism thrives in..
Cervix and fallopian tubes
__% to __% of untreated women of Gonorrhea develop..
Pelvic inflammatory disease (PID)
PID can lead to..
Scar formation in fallopian tubes leads to increased risk of ectopic pregnancy and sterility
Opthalmia neoinatorum
Gonococcal conjunctivitis of the newborn
Opthalmia neonatorum is acquired from..
Infected birth canal
Opthalmia neonaturum is prevented with..
Silver nitrate or erythromycin within 1 hour of birth