Chapter 16: Infectious Diseases Affecting the Skin: Part 3

Question 1

Causative agent of chickenpox

Answer 1

Varicella-zoster virus

Question 2

The varicella-zoster virus is a member of..

Answer 2

Herpesvirus family

Question 3

Varicella-zoster virus is a medium sized, _____ virus

Answer 3

Enveloped

Question 4

What kind of genome does the varicella-zoster virus have?

Answer 4

Double stranded DNA

Question 5

Varicella-zoster virus enters through..

Answer 5

Respiratory route

Question 6

Varicella-zoster virus replicates and moves the the skin via..

Answer 6

Blood stream Viremia

Question 7

After the chicken pox virus moves to the skin..

Answer 7

It infects living layers of skin and moves to adjacent cells, skin lesions appear

Question 8

After the chickenpox virus infects living layers of skin..

Answer 8

Infected cells swell and lyse

Question 9

After infected cells swell and lyse..

Answer 9

Release virus to enter sensory nerves (goes to cell ganglia and becomes latent, nerves are immunopriveledged so we do not attack these cells)

Question 10

Occurrence of shingles correlates with decline in..

Answer 10

Cell mediated
(Type I) immunity
Cytotoxic T cells

Question 11

When chickenpox virus is reactivated,

Answer 11

Latent virus within nerve cell replicates and is carried to the skin (recrudescence)

Question 12

Incidences of chickenpox increase in..

Answer 12

Winter and spring

Question 13

Viral incubation period of chicken pox is about..

Answer 13

2 weeks

Question 14

Prevention of chickenpox is aimed at..

Answer 14

Vaccination

Question 15

Chickenpox _____ vaccine was licensed in 1995

Answer 15

Attenuated

Question 16

Chickenpox vaccine is recommended for..

Answer 16

Healthy individuals 12 months and older

Question 17

Who should avoid the vaccine?

Answer 17

Pregnant women and immunocompromised patients

Question 18

Immunocompromised patients can be partially protected from chickenpox by..

Answer 18

Passive immunity via injection of zoster immune globulin (ZIG)

Question 19

Warts are caused by..

Answer 19

Papillomaviruses

Question 20

How do pappilomaviruses infect the skin?

Answer 20

Through minor abrasion

Question 21

Incubation period of pappilomaviruses

Answer 21

2 to 18 months

Question 22

Papillomavirus causes..

Answer 22

Small tumors called papillomas

Question 23

Warts rarely become..

Answer 23

Cancer

Question 24

Some sexually transmitted warts are associated with..

Answer 24

Cervical cancer

Question 25

Nearly half of skin warts disappear within __ years without treatment

Answer 25

2

Question 26

How does gardisil protect against cancer?

Answer 26

By protecting against viruses that cause cancer

Question 27

Papillomaviruses belong to..

Answer 27

Papovirus family

Question 28

Characteristics of papillomaviruses

Answer 28

Small non enveloped

Double stranded DNA genome

Question 29

Papillomaviruses can survive on a number of fomites including..

Answer 29

Wresting mats
Towels
Shower floors

Question 30

Superficial Cutaneous Mycoses

Answer 30

Group of diseases caused by numerous species of molds (type of fungi)

Question 31

Superficial Cutaneous Mycoses invade..

Answer 31

Nails, hair and keratinized layer of the skin

Question 32

Tinea capitis

Answer 32

Mycosis of the scalp

Question 33

Tinea axillaris

Answer 33

Mycosis of the underarm

Question 34

Tinea cruris

Answer 34

Mycosis of the groin (jock itch)

Question 35

Tinea pedis

Answer 35

Mycosis of the foot (athlete’s foot)