Chapter 21 - Gene Expression Flashcards

1
Q

copy of a segment of DNA that determines a gene that is then sent to the cytoplasm to then make a protein

A

RNA

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2
Q

what building block molecules are used to make proteins?

A

amino acids

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3
Q

Describe the DNA structure

A

“double helix”

long double stranded polymer

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4
Q

What does polymer mean?

A

that it’s made of building block molecule

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5
Q

before cells divide, what happens to DNA?

A

DNA condenses into butterfly shapes

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6
Q

What is the first step to gene expression?

A

Transcription

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7
Q

What is transcription?

A

converting information in DNA into RNA

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8
Q

sequence of bases that indicates where transcription should start

A

promoter

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9
Q

When does transcription stop?

A

when the enzyme reaches a termination (stop) sequence

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10
Q

what does mRNA stand for?

A

messenger RNA

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11
Q

‘coding’ segments that provide instructions for proteins

A

exon

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12
Q

noncoding segments

A

intron

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13
Q

20,000-25,000 genes produce > _________ proteins

A

100,000

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14
Q

Primary transcript can be edited in different ways to yield multiple mRNAs. This is called:

A

alternative splicing

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15
Q

converting the coded information in RNA into a protein

A

translation

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16
Q

translation is the switching of what?

A

“languages” from nucleotides to amino acids

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17
Q

carries DNA instructions for proteins out of the nucleus

A

mRNA

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18
Q

combines with proteins to form ribosomes

A

rRNA

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19
Q

What are ribosomes?

A

the sites of protein synthesis, made of RNA subunits

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20
Q

binds to an amino acid, then ferries the amino acid to sides on mRNA (“reading” the three base code)

A

tRNA

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21
Q

what is the removal of water called?

A

dehydration synthesis

22
Q

DNA is a stable molecule, and the process of replication is highly precise, but ______ sometimes occur

23
Q

DNA replication is also known as what?

A

DNA synthesis

24
Q

Change in DNA sequence caused by faulty replication

A

gene mutation

25
In cells destined to become gametes (sex cells), the mutation can be passed to _______
offspring
26
In point mutations, repair enzymes can recognize problems, cut the base out, stick in the correct base, and continue with transcription
true
27
additions of one or more bases
insertions
28
loss of one or more bases
deletions
29
flipping of sequence
inversions
30
copy a length of sequence or complete gene
duplications
31
change does not affect resulting amino acid sequence
silent mutation
32
there is a change in amino acid sequence, but it does not affect protein function
harmless mutation
33
new protein structure does not work as well
altered protein function
34
example of destruction of protein function
point mutation produces 'stop codon' in the wrong place mutation causes improper folding which stops protein from functioning
35
what helps us see color?
opsin genes produce proteins to help us see color
36
Lots of primates lack a 3rd opsin gene but we have a 3rd opsin gene. How?
Within our DNA, an old opsin gene was duplicated and over many generations, one of these copies acquired small mutations that allowed it to detect different wavelengths of light. Human color vision is due to duplication from a long time ago
37
describe a gene
sequence of nucleotides on a segment of DNA that determines a particular protein
38
Genes come in pairs. One from each of these:
One from maternal and one from paternal source. We get 2 copies
39
What can occur when there is a point mutation when making sister chromatids?
A wrong letter can cause a mutation, however, repair enzymes can recognize problems, correct it, and continue with transcription
40
DNA polmerases making copies of two strands, resulting in a copy of sister chromatid. Each new copy is half of the old copy.
DNA replication/synthesis
41
A machine that reads DNA strands making a complementary version then another reads it backwards
DNA polymerase
42
What are ribosomes made out of?
rRNA
43
building blocks of protein
amino acid
44
Sequences of DNA that do not translate to proteins
introns
45
Difference between introns and exons
Segments that remain are exons, they exit the nucleus. Introns insert DNA
46
when you make a copy of your DNA to be exported out of the nucleus
alternative splicing
47
In alternative splicing, a single segment of DNA can make a slightly different _______, which can make slightly different _______
RNA; proteins
48
Process occuring in DNA -> RNA
transcription
49
Process occuring in RNA -> Protein
Translation
50
What is the tail of mRNA that complements the sequence?
anticodon
51
RNA polymerase is a machine that makes a copy of one strand of DNA. The copy is called _______
RNA
52
________ produced the protein and suddenly the monkey was able to see color.
mRNA