Chapter 17 part 1: specific defenses of the host

Question 1

What is an activated B cell called?

Answer 1

plasma cell

Question 2

What does an activated B cell do?

Answer 2

B cell produce antibodies which recognizes specific pathogens

Question 3

What are the two types of T cells (using the CDs)?

Answer 3

CD8+ T cells (cytotoxic T cells)
CD4+ T cells (helper T cells)

Question 4

What is the function of a T killer cell? What or who does it kill?

Answer 4

Uses T cell receptor to destroy abnormal human cells by causing them to undergo apoptosis (requires an antigen presenting cell)

Question 5

What are the 4 different T cell products that kill?

Answer 5

perforin and granzyme
lymphotoxin
Fas (molecule that enacts programmed cell death)

Question 6

what is the job of any T helper cell?

Answer 6

Release signaling proteins that direct the immune system

Question 7

What is the difference between a helper 1 and a helper 2 cell?

Answer 7

Helper 1: Release hormones that activate inflammation, cytotoxic T cells and macrophages

Helper 2: Release hormones that stimulate B cells to produce antibodies

Question 8

What are the some of the alternate names for a TH3 CD4+ T cell?

Answer 8

CD25+ T cells
T s
T reg

Question 9

What happens when a CD 4+ T cell gets activated?

Answer 9

Release hormones that suppress immune cell activity and inhibit immune responses (anti-inflammatory)

Question 10

what is the function of IL-1?

Answer 10

very potent pro-inflammatory cytokine, also a pyrogen

Question 11

what is the function of IL-8?

Answer 11

attracts neutrophils to inflammation site

Question 12

what is the function of IL-10?

Answer 12

suppresses immune response (anti-inflammatory) released by T reg and Th3

Question 13

What is the only immune hormone that suppresses the immune system?

Answer 13

IL-10