Chapter 15: Body Fluids and Circulation Flashcards
Simple organisms like Sponges and Coelenterates circulate _____________ from their surroundings through their body cavity to facilitate the cells to exchange substances
water
Complex organisms use special fluids within their bodies to transport materials, ________________ is the most commonly used body fluid by most of the higher organisms including humans.
Blood
Another body fluid in higher organisms _____________ also helps in the transport of certain substances
Lymph(Tissue fluid)
Blood is a special _________________ tissue consisting of a fluid matrix, Plasma, and formed elements
Connective
____________ is a straw coloured, viscous fluid constituting nearly 55 % of the blood
Plasma
___________ percent of Plasma is Water and proteins contributes __________ percent of it
90 -92 %
6-8 %
__________ , ___________ and ____________ are the major proteins of Plasma
Fibrinogen
globulins
albumins
________________ proteins are needed for Clotting or coagulation of blood.
Fibrinogen
___________ proteins primarly are involved in defense mechanism of the body and the ___________ help in osmotic balance
Globulins
Albumins
Factors for coagulation or clotting of blood are also present in the plasma in an __________ form.
Inactive form
Plasma without the clotting factors is called ___________
serum
Erythrocytes, leucocytes and Platelets are collectively called _____________ and they constitute nearly _________ % of the blood
Formed elements
45 %
______________ or red blood cells (RBC**) are the most abundant of all the cells in blood.
Erythrocytes
A healthy adult man has on an average, _____millions to _____millions of RBCs mm-3
5
5.5
RBCs are formed in the _____________________ in the adults
Red Bone Marrow
RBCs are without nucleus in most of the mammals and are ___________ is shape
biconcave
RBC have a red coloured, iron containing complex protein called _____________
Haemoglobin
A healthy individual has ____________ gm of Haemoglobin in every 100 ml of blood..
12-16 gm
RBCs have an average life span of ________ days after which they are destroyed in the ___________(also known as Graveyard of RBCs)
120
Spleen (Graveyard of RBCs)
____________ are also known as white blood cells (WBC**) as they are colourless due to lack of Haemoglobin
Leucocytes
WBC are nucleated and are relatively lesser in number which averages _________________ mm-3 of blood.
6000 - 8000 mm-3
Two main categories of WBCs are _______________ and ____________
Granulocytes
Agranulocytes
Neutrophils, eosinophils and Basophils are different types of ______________
Granulocytes
____________ and ____________ are the agranulocytes
Lymphocytes
Monocytes
Neutrophils are the most abundant cells __________ % of the total WBCs, Basophils are the least _________ %
60-65 % of total WBCs
0.5 - 1 %
Neutrophils and Monocytes (6-8%) are ______________ cells which destroy foreign organisms entering the body.
Phagocytic
A phagocyte is a type of cell that can engulf and digest microorganisms
______________ secrete Histamine, serotonin, heparin and are involved in inflammatory reactions.
Basophils
__________________(2-3 %) resist infections and are also associated with allergic reactions.
Eosinophils
____________________ (20 -25 %) are of two major types B and T forms. Both B and T forms are responsible for Immune responses of the body,
Lymphocytes
Platelets also called ____________________, are cells fragments produced from _____________________ (Special cells in the bone marrow)
Thrombocytes
Megakaryocytes
Blood normally contains ________________________ platelets mm-3
150000 - 350000
____________ can release a variety of substances most of which are involved in the coagulation or clotting of blood
Platelets
A reduction is Platelets number can lead to ________________ disorders which will lead to excessive loss of blood from the body
Clotting
Two types of blood groupings the ____________ and ___________ are widely used all over the world
ABO
Rh
ABO grouping is based on the presence or absence of two surface ___________ on the RBCs namely A and B
Antigens
(chemicals that can induce immune response)
The blood of a donor has to be carefully matched with the blood of a recipient before any blood transfusion to avoid severe problems of ______________
Clumping(destruction of RBC)
Group ‘O’ blood can be donated to persons with any other blood group and hence ‘O’ group individuals are called ______________
universal donor
Person with ‘AB’ group can accept blood from persons with AB as well as the other groups of blood, therefor such persons are called ______________
Universal recipients
The Rh antigen similar to one present in ______________ monkeys, is also observed on the surface of RBCs of majority (nearly _____ %) of humans
Rhesus (Rh)
80%
The individuals with Rh antigen on the surface of RBCs are called _____________
and those in whom this antigen is absent are called _____________
Rh positive (Rh+ve)
Rh negative (Rh-ve)
A special case of Rh incompatibility (mismatching) has been observed between the ________blood of pregnant mother with ____________ blood of the foetus
Rh -ve (mother)
Rh +ve (foetus)
Rh antigen of the foetus do not get exposed to the Rh-ve blood of the mother in the first pregnancy as the two bloods are well separated by the placenta
During the delivery of the first child, there is a possibility of exposure of the maternal blood to small amounts of the Rh+ve blood from the foetus. In such cases the mother starts preparing ___________ against Rh antigen in her blood
Antibodies
in case of her next pregnancies, the Rh antibodies from the mother (Rh-ve) can leak into the blood of the foetus (Rh +ve) and destroy the foetal RBCs
In case of subsequent pregnancies, the Rh antibodies from the mother (Rh -ve) to the blood fo the foetus (Rh +ve) and destroy the foetal RBCs could be fatal to the foetus or could cause severe anaemia and jaundice to the baby, this condition is called __________________________
erythroblastosis foetalis
This can be avoided by administering anti-Rh antibodies to the mother immediately after the delivery of the first child.