chapter 15 Flashcards
3 ways hormones can interact on target cells
permissiveness
synergism
antagonism
permissiveness
one hormone cannot exert is effects without another hormone being present
synergism
more than one hormone produces the same effects on a target cell
antagonism
one or more hormones opposes the action of another hormone
3 factors that target cell activation depends on
Blood levels of the hormone.
Number of receptors on or in the target cell.
Affinity of binding between receptor and hormone.
Up-regulation
target cells form more receptors in response to the hormone
Down-regulation
target cells lose receptors in response to the hormone
Autocrines
exert effects on the same cells that secrete them
Paracrines
(tissue hormones) act locally and affect cells other than those that secrete them
Steroids
Synthesized from cholesterol. Gonadal and adrenocortical hormones
Lipid-soluble hormones
act on intracellular receptors that directly activate genes
Half-life
The time required for a hormone’s blood level to decrease by half
Humoral stimuli
Changing blood levels of ions and nutrients directly stimulates secretion of hormones
Neural stimuli
Nerve fibers stimulate hormone release
Hormonal stimuli
Hormones stimulate other endocrine organs to release their hormones
Center for emotional response and control center for functions such as blood pressure, body temperature, and water balance
Hypothalamus
hormone in charge of water balance in the body
Antidiuretic Hormone
Hormone involved in appetite control
leptin
3 ways hormones are removed from the body
Enzymatic degradation
Metabolism in liver
Excretion through the kidneys
Cells that produce growth hormone
Somatotrophs
Cells that produce prolactin
Lactotrophs
Antagonist to parathyroid hormone
Calcitonin
Cells that produce calcitonin
Parafollicular cells
Lack of TH leads to what?
Cretinism
What hypersecretion of TH leads to
Hyperthyroidism or Graves’ disease
Another name for parathyroid hormone
Parathormone
What inhibits PTH release?
Normal or high Calcium blood levels