Chapter 14 Flashcards

Infection, Disease, and Epidemiology

1
Q

Symbiosis def

A

to live together

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2
Q

microbiome def

A

symbiotic relationships with countless organisms

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3
Q

mutualism + or 0 or -

A

+ and +

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4
Q

commensalism + or - or 0

A

+ and 0

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5
Q

amensalism + or - or 0

A

.- and 0

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6
Q

parasitism 0 or - or +

A

+ and -

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7
Q

6 steps of the chain of infection

A

pathogen
reservoir
portal of exit
mode of transmission
portal of entry
susceptible host

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8
Q

reservoirs def

A

of infection are sites that maintains pathogens and are a source of infection

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9
Q

animal reservoir def

A

diseases that naturally spread from animal host to humans

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10
Q

human reservoirs def

A

asymptomatic carriers have the potential for more spreading

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11
Q

nonliving reservoirs def

A

soil water and food etc.
originate from contamination of feces

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12
Q

what are the 3 types of transmission

A

contact, vehicle, and vector

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12
Q

portals of exit ex

A

eyes nose mouth skin ears anus urethra

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12
Q

3 forms of contact transmission

A

direct, indirect, droplet

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13
Q

direct contact def

A

body contact btwen hosts

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14
Q

droplet transmission def

A

droplets of mucus in a close proximity

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14
Q

indirect contact def

A

spread via fomites , those are nonliving objects

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15
Q

vehicle transmission types

A

airborne, waterborne, food borne, bodily fluid

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16
Q

airborne ex

A

pathogens travel via aerosol

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17
Q

waterborne ex

A

many GI diseasesf

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18
Q

food borne ex

A

inadequate processing or storage

19
Q

bodily fluid ex

A

blood, urine, and saliva can carry pathogens

20
Q

biological vectors do what

A

transmit pathogens and serve as host for some stage of the pathogens life cycle

21
Q

ex of a vector transmision

A

biological vectors which are like mosquitos

22
3 main portals of entry
skin mucous membranes (respitory and GI) placenta
23
pathogenicity def
ability of a microorganism to cause disease
24
virulence def
degree of pathogenicity
25
virulence factor def
strategy or product employed by pathogen to cause infection
26
ex of virulence factors
adhesion, extracellular enzyems, toxins, antiphagocytic factors
27
adhesion establishes what
colonies within the host
28
what do attachment proteins help in
adhesion
29
what do some bacterial or fugal pathogens attach to each other to form
biofilm
30
what are extra cellular enzymes secreted by
by the pathogen
31
what do extracellular enzymes help the pathogen do
invade the hose, advoid immune system , and contribute to virulence
32
are toxins or extracellular enzymes always proteins
extracellular enzymes
33
toxins harm what
tissues. or they trigger host immune responses that cause damagee
34
phagocytosis def
engulfment by a host cell
35
antiphagocytic factos def
prevent phagocytosis, therefore virulence factors
36
bacterial capsule do what
prevent recognition of pathogen and they are slippery and hard to engulf
37
antiphagocytic chemicals do what
prevent fusion of lysosome and phagocytic vesicles and lysosome has enzymes that degrade proteins
38
symptoms def
subjective characteristics felt by the patient
39
signs def
objective manifestations of desease observed or measured by others
40
what are the 5 infection stages
incubation, prodromal, illness, decline, convalescenece
41
review each of the 5 stages of infection
no s or s, vague sympt, severs s and s, declining s and s, no signs of s or s
42
epidemiology def
the study of where and when disease occur, and how they are transmitted within populations
43
morbidity is what
of ppl getting sick/ total population %
44
mortality is what
of deaths/ total ppl sick %
45
john snow is the father of what
epidemiological studies (in london)
46
hospital epidemiology (HAI is what)
Healthcare associated infections
47
are HAI common
very common
48
whats the most effective way to reduce HAI
handwashing