Chapter 10: The Endocrine System and Chapter 11: The Lymphatic System Flashcards

1
Q

what are the 4 similarities between the endocrine and nervous systems?

A

-both release chemicals to stimulate organs/cells/tissues
-both respond to stimuli
-both mostly use the feedback mechanism
-both use the same chemicals(ex. E, NE)

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2
Q

how does the endocrine system secrete chemicals vs how does the nervous system secrete chemicals?

A

endocrine: releases hormones into the bloodstream

nervous: release neurotransmitters into only certain places

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3
Q

what are the lengths of responses for the endocrine and nervous systems?

A

endocrine: long term responses(changes last for a long period of time)

nervous: quick responses(last for less than 1 second)

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4
Q

what are the 3 ways to release a chemical?

A

-released by a neuron(neurotransmitter; nervous)
-released to a localized area(local regulator; endocrine)
-long distance regulator(endocrine)

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5
Q

what are the 3 different structures of hormones?

A

-amino acid derivatives
-peptide derivatives
-lipid derivatives

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6
Q

hormone structures: smallest structures; have the same atoms as amino acids; can be polar or nonpolar

A

amino acid derivatives

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7
Q

what are 4 examples of amino acid derivatives?

A

E, NE, T3, and T4

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8
Q

hormone structures: most common groups; has 2 classes, peptide and protein derivatives; can be polar or nonpolar

A

peptide derivatives

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9
Q

how many amino acids are peptide derivatives made up of?

A

2-8; only a few

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10
Q

how many amino acids are protein derivatives made up of?

A

lots; more than peptide derivatives

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11
Q

hormone structures: have 3 classes, steroid, fatty acid, and other

A

lipid derivatives

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12
Q

are steroid derivatives polar or nonpolar?

A

nonpolar

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13
Q

what are 3 examples of steroid hormones?

A

T, E, and P

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14
Q

what are fatty acid derivatives made up of?

A

eocosinoids

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15
Q

long chains of fatty acids

A

eocosinoids

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16
Q

what is one example of fatty acid derivatives?

A

prostaglandin

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17
Q

all are attracted to and dissolve in H2O; H2O cannot cross the cell membrane, therefore, these cannot cross the cell membrane either; there also must be a receptor located on the cell membrane

A

polar hormone

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18
Q

do not dissolve in H2O/blood so they can easily pass through the cell membrane; receptor must be on the inside of the cell membrane(in cytosol, organelle, or gene on a chromosome)

A

nonpolar hormone

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19
Q

what are the 3 methods that hormones are released?

A

-humoral response
-hormonal response
-neural response

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20
Q

methods of releasing hormones: group of hormones that are released because a level of a substance is too low or too high

A

humoral response

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21
Q

what are 4 examples of hormones released by humoral response?

A

GCG, INS, CT, and PTH

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22
Q

methods of releasing hormones: group of hormones that are released because another hormone was released

A

hormonal response

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23
Q

methods of releasing hormones: released as a neurotransmitter but goes into general circulation, making it a hormone

A

neural response

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24
Q

all of the cells, tissues, and organs used to clean and filter lymph fluid or attack pathogens

A

lymphatic system

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25
anything that causes disease/disease-causing agents
pathogen
26
what are the 6 types of pathogens?
-bacteria -fungus -parasites -protist -virus -bad body cells/cancerous cells
27
which two pathogens attack from the inside of cells and always only attack human body cells?
-viruses -bad body cells/cancerous cells
28
which is the only pathogen that does not use body cells as food and eat from the outside?
bad body cells/pathogens
29
which 4 pathogens are WBCs and never attack body cells?
-bacteria -fungus -parasites -protist
30
attack many different types of pathogens; use whatever weapons they have; do not reproduce themselves like other lymphocytes but call for extra help; attack with full force no matter what
nonspecific defense
31
attack only one specific pathogen; reproduces itself millions of times
specific defense
32
what are the 3 functions of the lymphatic system?
-cleans interstitial fluid -carry substances(debris, leftover enzymes, broken-up cells, proteins, lipids from digestive system, and hormones) -production and maturation/screening of lymphocytes
33
what are the 5 types of WBCs?
-monocytes -neutrophils -eosinophils -basophils -lymphocytes
34
which 4 WBCs use nonspecific defense?
-monocytes -neutrophils -eosinophils -basophils
35
which WBC uses specific defense?
lymphocytes
36
engulfs way more than others(super mario) and are big but only last for about 8 hours
macrophage
37
which 3 WBCs are phagocytes, which attack anything?
-monocytes -neutrophils -eosinophils
38
which WBC is a macrophage?
monocytes
39
fluid; carries lipids and WBCs; has clear fluid
lymph
40
walls are simple squamous so interstitial fluid goes into these
lymphatic capillaries
41
why are the walls of lymphatic capillaries simple squamous?
it is a smooth surface for the fluid to move and allows lymph to go in
42
capillaries merge and form vessels; walls are thicker; no new lymphocytes here
lymphatic vessels
43
what are the 2 lymphatic ducts?
thoracic duct and right lymphatic duct
44
takes old lymph into the circulatory system
lymphatic ducts
45
composed of loose connective tissue and lots of lymphocytes; do not have a hard capsule and can expand
lymph nodules
46
composed of loose connective tissue and lots of lymphocytes; has a hard, fibrous capsule around it and cannot expand
lymph nodes
47
located/sitting at the top of the heart; produces thymosins, which activate/produce/screen T cells; most active at the age of 2, is the largest at 10, and begins falling apart after this age, it is mostly gone by the age of 50
thymus
48
located behind and to the left of the stomach; filters blood-->cleans it from pathogens, bad cells, debris, etc.; has 2 parts: red pulp and white pulp
spleen
49
part of the spleen that contains lots of RBCs
red pulp
50
how many RBCs are there in the body?
about 60 trillion
51
part of the spleen that contains lots of WBCs
white pulp
52
located where the small and large intestine are connected; made up of lots of nodules; contains water, bacteria, and feces
appendix
53
most of these are found in body tissues; make up 20%-25% of the cells in the lymphatic system(about 1/5); has 3 types
lymphocytes
54
what are the 3 types of lymphocytes?
T cells, B cells, and NK cells
55
recognize their pathogen by their antigens(gang signs); made in bone marrow and mature/screen in the thymus; make up 80% of lymphocytes; 3 types
T cells
56
what are the 3 types of T cells?
Tc, TH, and Ts
57
attack by releasing enzymes(puts holes in the cell membrane); attacks bad cells(viruses, infected cells, cancer cells, and bacteria); uses cell-mediated responses
Tc(cytotoxic)
58
the response where the cell must be attacked from the inside
cell-mediated response
59
attack by releasing enzymes-->these cells call for help from Tc, B, and more WBCs
TH(helper)
60
activated to suppress the immune system to release an enzyme to promote apoptosis(cell suicide)
Ts(suppressor)
61
15%-20% of lymphocytes; made and screened/matured in bone marrow; called humoral response(attack pathogens in the fluid outside of the cell); attack by releasing antibodies(ninja stars)
B cells
62
made and screened/matured in bone marrow; 5%-10% of lymphocytes; called immunological surveillance; attack multiple antigens
NK cells(natural killer cells)
63
what are the 7 methods of nonspecific defense?
-skin and its secretions -phagocytes -immunological surveillance -interferons -complement proteins -inflammatory response -fever
64
nonspecific defense: lots of layers(dead) and it can speed up or slow down its reproductive rate; waterproof and rubbery; has holes to secrete fluid
skin/its secretions
65
what is secreted from the holes in the skin? (6)
saliva -tears -wax -sweat -oil -acid
66
which 3 of the skin secretions contain antibodies?
-saliva -tears -mucus
67
which 2 of the skin secretions are trappers?
mucus and wax
68
which one of the skin secretions contains salt?
sweat
69
which 3 of the skin secretions have a low pH?
sweat, oil, and acid
70
nonspecific defense: attack multiple things; attacks by endocytosis/engulfing; has 2 groups
phagocytes
71
4 examples of macrophages
-monocytes -microglia -dust cells of alveoli/resp. tract -Kueffler cells of liver
72
always the first to an infection site; free?
microphage
73
2 examples of microphages
neutrophils and eosinophils
74
what are the 2 characteristics of microphages?
diapedesis and positive chemotaxis
75
microphages having the ability to fit in small places; can get in and out of capillaries; only cells that can do this
diapedesis
76
the phagocytes are drawn towards chemicals
positive chemotaxis
77
what cells do immunological surveillance?
NK cells
78
nonspecific defense: only found in peripheral tissue; look for antigens(gang signs) of cells(bad cells: body, bacteria, fungus) that are recognized; always attack with enzymes called perforin
immunological surveillance
79
enzyme puts holes in cell membrane and fluid rushes in, making it explode and die
perforin
80
nonspecific defense: slows virus down; proteins released by any cell of the body to nearby cells; does not kill the virus from reproducing in the nearby cell
interferons
81
nonspecific defense: approximately 30 of these with different pathways; 1st one activates the 2nd one
complement proteins
82
what are the 3 functions of complement proteins?
-form MAC complex when combined with antibodies -activate phagocytes and lymphocytes -swell up the area
83
nonspecific defense: swelling response; 1st cell(mast cell/basophil) is found in peripheral tissues; mast cell sees an antigen(gang signs) and releases it chemicals into nearby tissues
inflammatory response
84
what are the 2 chemicals released by a mast cell in an inflammatory response?
histamine and heparin
85
increases the diameter of nearby capillaries
vasodialator
86
vasodilator; brings more fluid to the area; we want more fluid because it brings more cells such as WBCs and RBCs
histamine
87
anti-clotter; ex. meds that do not allow blood to clot, usually taken after a heart attack
heparin
88
nonspecific defense: damaged body cells/phagocytes/mast cells release pyrogen
fever
89
causes increased temperature of an area
pyrogen
90
why do we want to raise body temperatures?
to speed up reactions for ALL nonspecific defense mechanisms
91
what can a fever of 105 degrees cause? (2)
hallucinations and enzymes falling apart
92
not innate; also called acquired immunity or adaptive response; only uses T and B lymphocytes
specific response
93
in what cells can DNA be changed in?
lymphocytes
94
what does MHC complex stand for?
major histocompatibility complex
95
all body cells have this; works like a flagpole; can either have I or II
MHC complex
96
what cells have MHC I?
normal body cells
97
what cells have MHC II?
phagocytes
98
how do Tc cells attack?
by releasing enzymes
99
what does proliferation mean?
copies itself
100
what does clonal selection mean?
most attack and memory cells?
101
which Tc never actually attacks? 1st or 2nd; which one goes through proliferation and clonal selection?
1st never attacks and 2nd goes through proliferation and clonal selection
102
what enzymes are released by Tc to attack? (3)
lymphotoxin, cytokines, and perforin
103
enzymes: forces body cells' metabolism to stop
lymphotoxin
104
enzymes: forces apoptosis
cytokines
105
enzymes: makes holes in the cell membrane and causes it to explode
perforin
106
which TH goes through proliferation and clonal selection? 1st or 2nd
2nd
107
how do TH cells attack?
by releasing enzymes that call for help
108
what cells do enzymes call for help from? (2)
Tc and B
109
how do Ts cells attack?
release a suppressor enzyme
110
what cells do the suppressor enzyme released by Ts suppress? (2)
Tc and TH
111
what cells are suppressed by the suppressor enzyme released by Ts? (2)
Tc and TH
112
what type of response is done by B cells?
humoral
113
what do B cells use to attack
antibodies(ninja stars)
114
how many antibodies are secreted per second after it goes through proliferation and clonal selection? how long are they secreted for
2000-3000 per second for 2-3 days
115
what are the 5 functions of antibodies?
-neutralization -agglutination -bond with complement proteins to form MAC -activate phagocytes by marking pathogens -activate inflammatory response
116
antibodies completely surrounding pathogens
neutralization
117
antibodies forming clumps of lots of bacteria
agglutination
118
what is the difference between passive and active immunity?
passive: your immune system is attacking active: another person's immune system is attacking
119
what are 2 examples of passive immunity?
breastfeeding and chemotherapy
120
what are the 3 abnormal immune responses?
-autoimmune disorder -allergies/inappropriate response -virus attacking your immune system
121
T or B cells are attacking normal body cells instead of pathogens; inflammatory response?
autoimmune disorder
122
body attacks wrong antigens of substances that are not pathogens; inflammatory response
allergies/inappropriate response
123
what are 3 examples of autoimmune disorders?
-rheumatoid arthritis -crohn's disease -multiple sclerosis
124
what are 2 examples of viruses attacking your body cells?
HIV+ and AIDS
125
virus is inside of your cells(TH) and is hiding
HIV+
126
virus attacks and destroys TH cells; symptoms are cold, flu, pheumonia(these could all kill you with this)
AIDS
127
dirty part of the vessel
afferent vessel
128
clean part of the vessel
efferent vessel
129
what are effector cells?
T cells/attacker cells
130
where does the thoracic duct drain into?
everywhere except the right side of the body above the diaphragm
131
where does the right lymphatic duct drain into?
the right side of the body above the diaphragm