Ch13 Viruses, Viroids, Prions Flashcards

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1
Q

a virus nucleic acid core is protected by a protein coat called a

A

capsid

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2
Q

capsid subunits are called

A

capsomeres

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3
Q

some virus capsids are covered by an enevelope which is made of

A

lipids, proteins, carbs

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4
Q

primary genetic material of viruses

A

DNA or RNA (never both)

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5
Q

size range of viruses

A

10nm-1000nm

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6
Q

what determines the host range of viruses

A

the proteins on the surface of cells (“attachment sites” unique to organisms)

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7
Q

viruses require host cells to reproduce; thus they are considered

A

obligatory intracellular parasites

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8
Q

what are bacteriophages

A

viruses that infect bacteria

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9
Q

a group of viruses sharing the same genetic information and ecological niche (host range)

A

viral species

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10
Q

how we name viruses

A

no specific epithet,
descriptive common names + subspecies (if any)
ex: HIV-1

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11
Q

difference between lytic and lysogenic cycle (what happens to the phage DNA)

A
Lytic= phage DNA used to synthesize more virions
lysogenic= phage DNA integrates w bacterial chromosome
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12
Q

an acute infection is considered a viral ___-step growth curve

A

one-step

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13
Q

the period during viral multiplication when virions are not yet present (viruses are penetrating our cells)

A

eclipse period

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14
Q

infection in which virus remains in some cells of infected individual

A

persistant infection (hep c or b, hiv)

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15
Q

an infection in which the virus is dormant for a period of time

A

Latent infection (herpes, chickenpox-> shingles)

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16
Q

human wart virus/ hpv is caused by which viral family

A

papoviridae (human papillomavirus(genus))

17
Q

which viral family is associated w tumors (anal and cervical cancer)

A

papoviridae

18
Q

enteroviruses, Hep-A viruses, and rhinoviruses are in which virus family

A

picornaviridae

19
Q

80% of colds are caused by this viral species

A

rhinovirus

20
Q

rubella virus (Rubivirus) is in which viral family

A

togaviridae

21
Q

EEE, WEE, and chikungunya disease are caused by which viral family and species
how spread?

A

togaviridae, Rubella virus

transmitted via water droplets

22
Q

vesiculovirus and lyssavirus in which viral family

A

rhabdoviridae

23
Q

what lyssavirus causes?

which family?

A

rabies

rhabdoviridae

24
Q

filovirus causes what?

which family?

A
hemoragic fever (ebola) and internal bleeding (marburg virus)
filoviridae
25
Q

family of viruses that uses reverse transcriptase to produce DNA (RNA-> DNA), can inject genetic material into genome

A

retroviridae

26
Q

examples of retroviridae oncoviruses

A

RNA tumor viruses, HIV/AIDS, leukemia

27
Q

how prions are transmitted

A

ingestion, transplants, surgical equipment, inherited

28
Q

all viruses have

A

nucleic acid and a protein coat

29
Q

what causes spongiform encephalopathies like scrapie, C-J disease, and mad cow disease

A

prions

30
Q

how prions cause spongiform encephalopathies

A

prion binds to normal protein on cell surface,
turns normal into prion protein
cell begins producing more normal proteins
more turn into prion proteins
cell eventually envelopes these proteins
dies,
poke holes in grey matter of brain